Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Giusi Moffa"'
Publikováno v:
Journal of Statistical Software, Vol 105, Pp 1-31 (2023)
The R package BiDAG implements Markov chain Monte Carlo (MCMC) methods for structure learning and sampling of Bayesian networks. The package includes tools to search for a maximum a posteriori (MAP) graph and to sample graphs from the posterior distr
Externí odkaz:
https://doaj.org/article/6029218b32d0457a8897ec04aaa04bcc
Autor:
Narayan Sharma, Giusi Moffa, René Schwendimann, Olga Endrich, Dietmar Ausserhofer, Michael Simon
Publikováno v:
BMC Health Services Research, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background High bed-occupancy (capacity utilization) rates are commonly thought to increase in-hospital mortality; however, little evidence supports a causal relationship between the two. This observational study aimed to assess three time-v
Externí odkaz:
https://doaj.org/article/2402c2e098c14d7e816af35b74df3372
Autor:
Matthias Briel, Sally Hopewell, Arnav Agarwal, Joerg J Meerpohl, Jason W Busse, Patrick Hong, Matthias Schwenkglenks, Szimonetta Lohner, Benjamin Speich, Viktoria Gloy, Erik von Elm, Sirintip Sricharoenchai, Benjamin Kasenda, Stefan Schandelmaier, Dominik Mertz, Anette Blümle, Jacqueline Wong, Alain Amstutz, Belinda Von Niederhäusern, Alain Nordmann, Giusi Moffa, Dmitry Gryaznov, Elena Ojeda-Ruiz, Ayodele Odutayo, Yuki Tomonaga, Christiane Pauli-Magnus, Karin Bischoff, Katharina Wollmann, Laura Rehner, Katharina Klatte, Nilabh Ghosh, Ala Taji Heravi, Ngai Chow, Kimberly A McCord - De Iaco, Ramon Saccilotto, Lars Hemkens
Publikováno v:
BMJ Open, Vol 12, Iss 5 (2022)
Objectives Comprehensive protocols are key for the planning and conduct of randomised clinical trials (RCTs). Evidence of low reporting quality of RCT protocols led to the publication of the Standard Protocol Items: Recommendations for Interventional
Externí odkaz:
https://doaj.org/article/739be36abe1e4ed9bc29877e5be299ae
Autor:
Amanda Katherina Herbrand, Andreas Michael Schmitt, Urban Novak, Benjamin Kasenda, Giusi Moffa, Lars Hemkens, Martin Walter, Markus Jörger
Publikováno v:
BMJ Open, Vol 12, Iss 5 (2022)
Objective To describe the characteristics and the survival of patients with cancer with intended off-label use (OLU) cancer treatment and reimbursement request.Design Cohort study using medical record data.Setting Three major cancer centres in Switze
Externí odkaz:
https://doaj.org/article/d7f317e301224cfaa101dc10daa357cc
Autor:
Dmitry Gryaznov, Ayodele Odutayo, Belinda von Niederhäusern, Benjamin Speich, Benjamin Kasenda, Elena Ojeda-Ruiz, Anette Blümle, Stefan Schandelmaier, Dominik Mertz, Yuki Tomonaga, Alain Amstutz, Christiane Pauli-Magnus, Viktoria Gloy, Karin Bischoff, Katharina Wollmann, Laura Rehner, Szimonetta Lohner, Joerg J. Meerpohl, Alain Nordmann, Katharina Klatte, Nilabh Ghosh, Ala Taji Heravi, Jacqueline Wong, Ngai Chow, Patrick Jiho Hong, Kimberly Mc Cord, Sirintip Sricharoenchai, Jason W. Busse, Arnav Agarwal, Ramon Saccilotto, Matthias Schwenkglenks, Giusi Moffa, Lars G. Hemkens, Sally Hopewell, Erik von Elm, Matthias Briel
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-13 (2020)
Abstract Background Clearly structured and comprehensive protocols are an essential component to ensure safety of participants, data validity, successful conduct, and credibility of results of randomized clinical trials (RCTs). Funding agencies, rese
Externí odkaz:
https://doaj.org/article/c74de565372d47f49657913f07545ea7
Autor:
Benjamin Kasenda, Junhao Liu, Yu Jiang, Byron Gajewski, Cen Wu, Erik von Elm, Stefan Schandelmaier, Giusi Moffa, Sven Trelle, Andreas Michael Schmitt, Amanda K. Herbrand, Viktoria Gloy, Benjamin Speich, Sally Hopewell, Lars G. Hemkens, Constantin Sluka, Kris McGill, Maureen Meade, Deborah Cook, Francois Lamontagne, Jean-Marc Tréluyer, Anna-Bettina Haidich, John P. A. Ioannidis, Shaun Treweek, Matthias Briel
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-7 (2020)
Abstract Background Poor recruitment of patients is the predominant reason for early termination of randomized clinical trials (RCTs). Systematic empirical investigations and validation studies of existing recruitment models, however, are lacking. We
Externí odkaz:
https://doaj.org/article/c79d263ef5fd4452bc2bda724a308791
Autor:
Andrea L Pusic, Matthias Schwenkglenks, Karin Ribi, Lars G Hemkens, Jane Shaw, Christian Kurzeder, Shelley Potter, Joerg Heil, Heiner C Bucher, Frank Zimmermann, Sherko Kuemmel, Elisabeth A Kappos, Alexandra Schulz, Meredith M Regan, Giusi Moffa, Yves Harder, Mathias K Fehr, Thomas Holzbach, Jian Farhadi, Colin Simonson, Michael Knauer, Ralph Verstappen, Daniel Zwahlen, Rosine Mucklow, Vesna Bjelic-Radisic, Amelia Chiorescu, Yoon S Chun, Subrina Farah, Chen Xiaosong, Linda Nigard, Roland Reitsamer, Maik Hauschild, Ilario Fulco, Christoph Tausch, Thomas Fischer, Dimitri Sarlos, Mihai A Constantinescu, Judith E Lupatsch, Florian Fitzal, Zoltan Matrai, Jana de Boniface, Martin Haug, Walter P Weber
Publikováno v:
BMJ Open, Vol 11, Iss 9 (2021)
Introduction The emphasis on aesthetic outcomes and quality of life (QoL) has motivated surgeons to develop skin-sparing or nipple-sparing mastectomy (SSM/ NSM) for breast cancer treatment or prevention. During the same operation, a so-called immedia
Externí odkaz:
https://doaj.org/article/bcf28dbf10064f8797b704023dc5f952
Autor:
Dominik Glinz, Kimberly A. Mc Cord, Giusi Moffa, Soheila Aghlmandi, Ramon Saccilotto, Andreas Zeller, Andreas F. Widmer, Julia Bielicki, Andreas Kronenberg, Heiner C. Bucher
Publikováno v:
Contemporary Clinical Trials Communications, Vol 21, Iss , Pp 100712- (2021)
Introduction: Antibiotic consumption is highest in primary care, and antibiotic overuse furthers antimicrobial resistance. In our recently published pilot-RCT, we used monthly aggregated claims data to provide personalized antibiotic prescription fee
Externí odkaz:
https://doaj.org/article/a7eaa25198954a4b88aff38c0767b09a
Autor:
Jack Kuipers, Thomas Thurnherr, Giusi Moffa, Polina Suter, Jonas Behr, Ryan Goosen, Gerhard Christofori, Niko Beerenwinkel
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Tumour heterogeneity hinders translation of large-scale genomic data into the clinic. Here the authors develop a method for the stratification of cancer patients based on the molecular gene status, including genetic interactions, rather than clinico-
Externí odkaz:
https://doaj.org/article/0b115bdf44cb494d927bace641aa4ed3
Publikováno v:
Swiss Medical Weekly, Vol 149, Iss 4950 (2019)
BACKGROUND Secondary hyperparathyroidism is common in patients with end-stage chronic kidney disease. If drug therapy fails, total parathyroidectomy with autotransplantation of parathyroid tissue into the forearm (PTX-AT) is the most widely used pro
Externí odkaz:
https://doaj.org/article/266912feef3942759120e85fb6ff9862