Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Giuseppina Ioele"'
Autor:
Elisabetta Mazzotta, Martina Chieffallo, Rita Muzzalupo, Miriana Spingola, Paolino Caputo, Martina Romeo, Giuseppina Ioele
Publikováno v:
Molecules, Vol 29, Iss 14, p 3329 (2024)
Caffeic acid (CA), a hydrophobic polyphenol with various pharmacological activities, exhibits a low aqueous solubility and sensitivity to light. In order to improve its chemical properties and overcome the limits in its application, the compound was
Externí odkaz:
https://doaj.org/article/b801048d0d924aa09d19dbe2d86eda5d
Autor:
Michele De Luca, Maria Antonietta Occhiuzzi, Bruno Rizzuti, Giuseppina Ioele, Gaetano Ragno, Antonio Garofalo, Fedora Grande
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1600-1609 (2022)
Letrozole is one of the most prescribed drugs for the treatment of breast cancer in post-menopausal women, and it is endowed with selective peripheral aromatase inhibitory activity. The efficacy of this drug is also a consequence of its long-lasting
Externí odkaz:
https://doaj.org/article/63a9b80e702a4829a800e614720c6723
Autor:
Martina Chieffallo, Michele De Luca, Fedora Grande, Maria Antonietta Occhiuzzi, Miyase Gözde Gündüz, Antonio Garofalo, Giuseppina Ioele
Publikováno v:
Pharmaceutics, Vol 16, Iss 2, p 206 (2024)
1,4-dihydropyridines (1,4-DHPs) are widely recognized as highly effective L-type calcium channel blockers with significant therapeutic benefits in the treatment of cardiovascular disorders. 1,4-DHPs can also target T-type calcium channels, making the
Externí odkaz:
https://doaj.org/article/118e6946001645338054141639f4229d
Autor:
Michele De Luca, Giuseppina Ioele, Fedora Grande, Maria Antonietta Occhiuzzi, Martina Chieffallo, Antonio Garofalo, Gaetano Ragno
Publikováno v:
Molecules, Vol 28, Iss 12, p 4661 (2023)
Virgin coconut oil (VCO) is a functional food with important health benefits. Its economic interest encourages fraudsters to deliberately adulterate VCO with cheap and low-quality vegetable oils for financial gain, causing health and safety problems
Externí odkaz:
https://doaj.org/article/38bb3b2888ea4c98bd9e19bc2ac92585
Autor:
Michele De Luca, Donatella Restuccia, Umile Gianfranco Spizzirri, Pasquale Crupi, Giuseppina Ioele, Beatrice Gorelli, Maria Lisa Clodoveo, Simona Saponara, Francesca Aiello
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 622 (2023)
An ultrasound-assisted extraction method, employing ethanol and water as solvents at low temperature (30 °C) and reduced time (15 min), was proposed to extract bioactive molecules from different cultivars (Magliocco Canino, Magliocco Rosato, Gagliop
Externí odkaz:
https://doaj.org/article/ff0056aee311471da52fea595a048868
Autor:
Fedora Grande, Giuseppina Ioele, Anna Caruso, Maria Antonietta Occhiuzzi, Hussein El-Kashef, Carmela Saturnino, Maria Stefania Sinicropi
Publikováno v:
Applied Sciences, Vol 13, Iss 1, p 349 (2022)
Carbazole derivatives have gained a lot of attention in medicinal chemistry over the last few decades due to their wide range of biological and pharmacological properties, including antibacterial, antitumor, antioxidant, and anti-inflammatory activit
Externí odkaz:
https://doaj.org/article/589f222d6ce3425f8ba96066c4cfe747
Autor:
Giuseppina Ioele, Martina Chieffallo, Maria Antonietta Occhiuzzi, Michele De Luca, Antonio Garofalo, Gaetano Ragno, Fedora Grande
Publikováno v:
Molecules, Vol 27, Iss 17, p 5436 (2022)
In past decades, anticancer research has led to remarkable results despite many of the approved drugs still being characterized by high systemic toxicity mainly due to the lack of tumor selectivity and present pharmacokinetic drawbacks, including low
Externí odkaz:
https://doaj.org/article/554a35f1821041bdbce2fd319785557c
Autor:
Giuseppina Ioele, Fedora Grande, Michele De Luca, Maria Antonietta Occhiuzzi, Antonio Garofalo, Gaetano Ragno
Publikováno v:
Molecules, Vol 26, Iss 19, p 5989 (2021)
The present paper provides an updated overview of the methodologies applied in photodegradation studies of non-steroidal anti-inflammatory drugs. Photostability tests, performed according to international standards, have clearly demonstrated the phot
Externí odkaz:
https://doaj.org/article/b4bb487ce23a425192289d479818f07e
Autor:
Fedora Grande, Maria Antonietta Occhiuzzi, Maria Rosaria Perri, Giuseppina Ioele, Bruno Rizzuti, Giancarlo Statti, Antonio Garofalo
Publikováno v:
Molecules, Vol 26, Iss 18, p 5718 (2021)
Tacle® is a citrus fruit obtained from the crossbreeding of Clementine and Tarocco cultivars. This fruit retains a promising nutraceutical potential most likely due to a high content in polyphenols, among which the main constituents are the two glyc
Externí odkaz:
https://doaj.org/article/580c2a413c124249b79437e778255d25
Autor:
Fedora Grande, Francesca Giordano, Maria Antonietta Occhiuzzi, Carmine Rocca, Giuseppina Ioele, Michele De Luca, Gaetano Ragno, Maria Luisa Panno, Bruno Rizzuti, Antonio Garofalo
Publikováno v:
Molecules, Vol 26, Iss 13, p 3940 (2021)
The antitumor activity of certain anti-inflammatory drugs is often attributed to an indirect effect based on the inhibition of COX enzymes. In the case of anti-inflammatory prodrugs, this property could be attributed to the parent molecules with mech
Externí odkaz:
https://doaj.org/article/34b8da0bc0274fbca49c6ebe3ae8bf98