Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Giuseppe Uras"'
Autor:
Giuseppe Uras, Xinuo Li, Alessia Manca, Antonella Pantaleo, Marco Bo, Jinyi Xu, Stephanie Allen, Zheying Zhu
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14794 (2022)
Alzheimer’s disease (AD) is characterized by an initial accumulation of amyloid plaques and neurofibrillary tangles, along with the depletion of cholinergic markers. The currently available therapies for AD do not present any disease-modifying effe
Externí odkaz:
https://doaj.org/article/fd3fd6f14e44467d91e3159a9166d6c1
Autor:
Giuseppe Uras, Alessia Manca, Pengfei Zhang, Zsuzsa Markus, Natalie Mack, Stephanie Allen, Marco Bo, Shengtao Xu, Jinyi Xu, Marios Georgiou, Zheying Zhu
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Alzheimer’s disease is a neurodegenerative disease characterized by disrupted memory, learning functions, reduced life expectancy, and locomotor dysfunction, as a result of the accumulation and aggregation of amyloid peptides that cause neuronal da
Externí odkaz:
https://doaj.org/article/e0ce13dc077045ec83b41b06e68f29a3
Autor:
Cristina Manis, Alessia Manca, Antonio Murgia, Giuseppe Uras, Pierluigi Caboni, Terenzio Congiu, Gavino Faa, Antonella Pantaleo, Giacomo Cao
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6876 (2022)
Erythrocytes are highly specialized cells in human body, and their main function is to ensure the gas exchanges, O2 and CO2, within the body. The exposure to microgravity environment leads to several health risks such as those affecting red blood cel
Externí odkaz:
https://doaj.org/article/0c1d82dea5c84bfdbc95a828fb771056
Autor:
Nadezhda Barvitenko, Mohammad Ashrafuzzaman, Alfons Lawen, Elisaveta Skverchinskaya, Carlota Saldanha, Alessia Manca, Giuseppe Uras, Muhammad Aslam, Antonella Pantaleo
Publikováno v:
Membranes, Vol 12, Iss 2, p 205 (2022)
Chronic low-grade vascular inflammation and endothelial dysfunction significantly contribute to the pathogenesis of cardiovascular diseases. In endothelial cells (ECs), anti-inflammatory or pro-inflammatory signaling can be induced by different patte
Externí odkaz:
https://doaj.org/article/e3e9d596859f49c89389906419425776
Autor:
Nadezhda Barvitenko, Muhammad Aslam, Alfons Lawen, Carlota Saldanha, Elisaveta Skverchinskaya, Giuseppe Uras, Alessia Manca, Antonella Pantaleo
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 7967 (2021)
Changes in plasma membrane curvature and intracellular ionic strength are two key features of cell volume perturbations. In this hypothesis we present a model of the responsible molecular apparatus which is assembled of two molecular motors [non-musc
Externí odkaz:
https://doaj.org/article/c0e14d4af8d04d8d80a35e92c0ad8e9c
Autor:
Nadezhda Barvitenko, Elisaveta Skverchinskaya, Alfons Lawen, Elena Matteucci, Carlota Saldanha, Giuseppe Uras, Alessia Manca, Muhammad Aslam, Antonella Pantaleo
Publikováno v:
Antioxidants, Vol 10, Iss 6, p 904 (2021)
Endothelial cells (ECs) are exposed to molecular dioxygen and its derivative reactive oxygen species (ROS). ROS are now well established as important signaling messengers. Excessive production of ROS, however, results in oxidative stress, a significa
Externí odkaz:
https://doaj.org/article/70a237f68c3c41af96852dd783a60e4c
Autor:
Marco Bo, Seyedesomaye Jasemi, Giuseppe Uras, Gian Luca Erre, Giuseppe Passiu, Leonardo A. Sechi
Publikováno v:
Microorganisms, Vol 8, Iss 10, p 1459 (2020)
Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disease characterized by chronic erosive polyarthritis. A complex interaction between a favorable genetic background, and the presence of a specific immune response against a broad-spect
Externí odkaz:
https://doaj.org/article/13224038308445a49f3cf185b7ebf9c5
Autor:
Alessia Manca, Stephanie Allen, Pengfei Zhang, Natalie A. Mack, Marco Bo, Marios Georgiou, Jinyi Xu, Shengtao Xu, Giuseppe Uras, Zheying Zhu, Zsuzsa Markus
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Frontiers in Neuroscience
Frontiers in Neuroscience
Alzheimer’s disease is a neurodegenerative disease characterized by disrupted memory, learning functions, reduced life expectancy, and locomotor dysfunction, as a result of the accumulation and aggregation of amyloid peptides that cause neuronal da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::626dcf1473e7d42595b481472f0fe51b
Autor:
Shengtao Xu, Zheying Zhu, Jie Liu, Pengfei Zhang, Qi Gong, Giuseppe Uras, Ying Yin, Stephanie Allen, Hai-Yan Zhang, Hong Yao, Qin Shuai, Jinyi Xu, Bai Renren, Xinuo Li
Publikováno v:
Journal of medicinal chemistry. 64(11)
Based on a multitarget strategy, a series of novel tacrine-pyrimidone hybrids were identified for the potential treatment of Alzheimer's disease (AD). Biological evaluation results demonstrated that these hybrids exhibited significant inhibitory acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae950d099a986d42649c30242600b5ac
https://pubmed.ncbi.nlm.nih.gov/34024109
https://pubmed.ncbi.nlm.nih.gov/34024109
Autor:
Carlota Saldanha, Alfons Lawen, Elisaveta Skverchinskaya, Muhammad Aslam, Giuseppe Uras, Nadezhda Barvitenko, Antonella Pantaleo, Alessia Manca
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 7967, p 7967 (2021)
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 7967, p 7967 (2021)
© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Chan
Chan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc98c6dd97883ffe2968b014a84d50e