Zobrazeno 1 - 10
of 259
pro vyhledávání: '"Giuseppe Pugliese"'
Autor:
Monia Garofolo, Martina Vitale, Giuseppe Penno, Anna Solini, Emanuela Orsi, Valeria Grancini, Enzo Bonora, Cecilia Fondelli, Roberto Trevisan, Monica Vedovato, Antonio Nicolucci, Giuseppe Pugliese, the Renal Insufficiency And Cardiovascular Events (RIACE) Study Group
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Background A Chronic Kidney Disease (CKD) Epidemiology Collaboration (EPI) formula not including a Black race coefficient has been recently developed and is now recommended in the US. The new (2021) equation was shown to yield higher estimat
Externí odkaz:
https://doaj.org/article/88dc433b01c34a3a83b5353045153864
Autor:
Chiara Chiavelli, Malvina Prapa, Giulia Rovesti, Marco Silingardi, Giovanni Neri, Giuseppe Pugliese, Lucia Trudu, Massimiliano Dall’Ora, Giulia Golinelli, Giulia Grisendi, Jonathan Vinet, Marco Bestagno, Carlotta Spano, Roberto Vito Papapietro, Roberta Depenni, Katia Di Emidio, Anna Pasetto, Daniela Nascimento Silva, Alberto Feletti, Silvia Berlucchi, Corrado Iaccarino, Giacomo Pavesi, Massimo Dominici
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-9 (2024)
Abstract Glioblastoma (GBM) remains a deadly tumor. Treatment with chemo-radiotherapy and corticosteroids is known to impair the functionality of lymphocytes, potentially compromising the development of autologous CAR T cell therapies. We here genera
Externí odkaz:
https://doaj.org/article/b35ac19b1e9c4db4933d30af0c9b01a2
Autor:
Martina Vitale, Emanuela Orsi, Anna Solini, Monia Garofolo, Veronica Resi, Enzo Bonora, Cecilia Fondelli, Roberto Trevisan, Monica Vedovato, Giuseppe Penno, Giuseppe Pugliese
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background Foot ulcers and/or infections are common long-term complications of diabetes and are associated with increased mortality, especially from cardiovascular disease, though only a few studies have investigated the independent contribu
Externí odkaz:
https://doaj.org/article/13d8ff083d154dce96637ac2c1038816
Autor:
Jonida Haxhi, Martina Vitale, Lorenza Mattia, Chiara Giuliani, Massimo Sacchetti, Giorgio Orlando, Carla Iacobini, Stefano Menini, Silvano Zanuso, Antonio Nicolucci, Stefano Balducci, Giuseppe Pugliese
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundCurrent guidelines for nonalcoholic fatty liver disease (NAFLD) recommend high volumes and/or intensities of physical activity (PA), the achievement of which generally requires participation in supervised exercise training programs that how
Externí odkaz:
https://doaj.org/article/235def33cd724f0fae1a8efdcefad891
Autor:
Viviana Casagrande, Stefano Menini, Chiara Internò, Giuseppe Pugliese, Massimo Federici, Rossella Menghini
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2024)
IntroductionType 1 diabetes mellitus (T1DM) development involves a complex interplay of genetic, environmental, and immunological factors. By modulating the activity of proteases and receptors, the protein tissue inhibitor of metalloproteinase 3 (TIM
Externí odkaz:
https://doaj.org/article/f6790e3fbeaf407599870b22a1def2fa
Publikováno v:
Cells, Vol 13, Iss 9, p 763 (2024)
The adipose organ adapts and responds to internal and environmental stimuli by remodeling both its cellular and extracellular components. Under conditions of energy surplus, the subcutaneous white adipose tissue (WAT) is capable of expanding through
Externí odkaz:
https://doaj.org/article/3ba6687b86eb4de7aa8628459d49e8c6
Autor:
David M. Davies, Giuseppe Pugliese, Ana C. Parente Pereira, Lynsey M. Whilding, Daniel Larcombe-Young, John Maher
Publikováno v:
Biology, Vol 13, Iss 3, p 196 (2024)
γδ T-cells provide immune surveillance against cancer, straddling both innate and adaptive immunity. G115 is a clonal γδ T-cell receptor (TCR) of the Vγ9Vδ2 subtype which can confer responsiveness to phosphoantigens (PAgs) when genetically intr
Externí odkaz:
https://doaj.org/article/94f2ea0c2cc943639c1beda8e453bd5b
Autor:
Emanuela Orsi, Anna Solini, Giuseppe Penno, Enzo Bonora, Cecilia Fondelli, Roberto Trevisan, Monica Vedovato, Franco Cavalot, Olga Lamacchia, Jonida Haxhi, Antonio Nicolucci, Giuseppe Pugliese, for the Renal Insufficiency And Cardiovascular Events (RIACE) Study Group
Publikováno v:
Cardiovascular Diabetology, Vol 21, Iss 1, Pp 1-12 (2022)
Abstract Background An “obesity paradox” for mortality has been shown in chronic disorders such as diabetes, and attributed to methodological bias, including the use of body mass index (BMI) for obesity definition. This analysis investigated the
Externí odkaz:
https://doaj.org/article/3dbe2c92fc4f45dfaf8955a29f876df8
Autor:
Carla Iacobini, Martina Vitale, Federica Sentinelli, Jonida Haxhi, Giuseppe Pugliese, Stefano Menini
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2217 (2024)
The (pro)renin receptor ((P)RR), a versatile protein found in various organs, including the kidney, is implicated in cardiometabolic conditions like diabetes, hypertension, and dyslipidemia, potentially contributing to organ damage. Importantly, chan
Externí odkaz:
https://doaj.org/article/1007103539974815a2c0a1b146a62efe
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
The hypoxia-inducible factor-1α (HIF-1α), a key player in the adaptive regulation of energy metabolism, and the M2 isoform of the glycolytic enzyme pyruvate kinase (PKM2), a critical regulator of glucose consumption, are the main drivers of the met
Externí odkaz:
https://doaj.org/article/2848431bfec34fcd8c27a86f0c4cf953