Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Giuseppe Persico"'
Autor:
Jacopo Di Lucente, Giuseppe Persico, Zeyu Zhou, Lee-Way Jin, Jon J. Ramsey, Jennifer M. Rutkowsky, Claire M. Montgomery, Alexey Tomilov, Kyoungmi Kim, Marco Giorgio, Izumi Maezawa, Gino A. Cortopassi
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract The Ketogenic Diet (KD) improves memory and longevity in aged C57BL/6 mice. We tested 7 months KD vs. control diet (CD) in the mouse Alzheimer’s Disease (AD) model APP/PS1. KD significantly rescued Long-Term-Potentiation (LTP) to wild-type
Externí odkaz:
https://doaj.org/article/5b5695c6167f4f8187ed0d0bf77fabd3
Autor:
Cristina Andreani, Caterina Bartolacci, Giuseppe Persico, Francesca Casciaro, Stefano Amatori, Mirco Fanelli, Marco Giorgio, Mirco Galié, Daniele Tomassoni, Junbiao Wang, Xiaoting Zhang, Gregory Bick, Roberto Coppari, Cristina Marchini, Augusto Amici
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-22 (2023)
Abstract The histone deacetylase sirtuin 6 (SIRT6) has been endowed with anti-cancer capabilities in many tumor types. Here, we investigate the impact of SIRT6-overexpression (SIRT6-OE) in Delta16HER2 mice, which are a bona fide model of HER2-positiv
Externí odkaz:
https://doaj.org/article/8139fbb56d614a27a117f5c1c6e0780d
Autor:
Aurora Diotallevi, Federica Bruno, Germano Castelli, Giuseppe Persico, Gloria Buffi, Marcello Ceccarelli, Daniela Ligi, Ferdinando Mannello, Fabrizio Vitale, Mauro Magnani, Luca Galluzzi
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 4, p e0012085 (2024)
BackgroundIn the Mediterranean basin, three Leishmania species have been identified: L. infantum, L. major and L. tropica, causing zoonotic visceral leishmaniasis (VL), zoonotic cutaneous leishmaniasis (CL) and anthroponotic CL, respectively. Despite
Externí odkaz:
https://doaj.org/article/09896a0966874b758b7adbd5b52acbc3
Autor:
Massimo Stendardo, Chiara Renzi, Rani Pallavi, Niccolò Roda, Valentina Gambino, Francesca Casciaro, Giuseppe Persico, Marco Giorgio
Publikováno v:
Cancer Reports, Vol 6, Iss 1, Pp n/a-n/a (2023)
Abstract Background Early‐life stress due to poor parental care has been suggested to increase cancer risk, though, so far, no experimental evidence established a link between defective parental behavior and spontaneous tumorigenesis in progeny. Es
Externí odkaz:
https://doaj.org/article/6bc3b2626a5e4833bd9f36943994d48d
Autor:
Francesca Casciaro, Francesca Beretti, Martina Gatti, Giuseppe Persico, Emma Bertucci, Marco Giorgio, Tullia Maraldi
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 430 (2023)
Human amniotic fluid cells (hAFSCs) are a fascinating foetal cell-type that have important stem cell characteristics; however, they are a heterogeneous population that ranges from totally differentiated or progenitor cells to highly multipotent stem
Externí odkaz:
https://doaj.org/article/52d6f28fa4414a68a7861e7893533ab5
Autor:
Giuseppe Persico, Francesca Casciaro, Stefano Amatori, Martina Rusin, Francesco Cantatore, Amalia Perna, Lavinia Alberi Auber, Mirco Fanelli, Marco Giorgio
Publikováno v:
Cells, Vol 11, Iss 4, p 734 (2022)
Background: Epigenetic remodeling is emerging as a critical process for both the onset and progression of Alzheimer’s disease (AD), the most common form of neurodegenerative dementia. However, it is not clear to what extent the distribution of hist
Externí odkaz:
https://doaj.org/article/27fde7ddf9fe45af9568a43e3aa2118b
Autor:
Stefano Amatori, Giuseppe Persico, Claudio Paolicelli, Roman Hillje, Nora Sahnane, Francesco Corini, Daniela Furlan, Lucilla Luzi, Saverio Minucci, Marco Giorgio, Pier Giuseppe Pelicci, Mirco Fanelli
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-15 (2018)
Abstract Background The introduction of pathology tissue-chromatin immunoprecipitation (PAT-ChIP), a technique allowing chromatin immunoprecipitation (ChIP) from formalin-fixed paraffin-embedded (FFPE) tissues, has extended the application of chromat
Externí odkaz:
https://doaj.org/article/211ea910424b4a6287be5220da1af964
Autor:
Alfredo Errico Provenzano, Stefano Amatori, Maria Gemma Nasoni, Giuseppe Persico, Sergio Russo, Anna Rita Mastrogiacomo, Alessandro Gambarara, Mirco Fanelli
Publikováno v:
Cellular Physiology and Biochemistry, Vol 46, Iss 1, Pp 389-400 (2018)
Background/Aims: Life on Earth is constantly exposed to electromagnetic fields (EMFs) and the effects induced by EMFs on biological systems have been extensively studied producing different and sometimes contradictory results. Extremely low-frequency
Externí odkaz:
https://doaj.org/article/a163d14621a54685a0109e3dbd31fa9a
Autor:
Francesca Casciaro, Giuseppe Persico, Martina Rusin, Stefano Amatori, Claire Montgomery, Jennifer R. Rutkowsky, Jon J. Ramsey, Gino Cortopassi, Mirco Fanelli, Marco Giorgio
Publikováno v:
Epigenomes, Vol 5, Iss 4, p 26 (2021)
Background: Women represent the majority of Alzheimer’s disease patients and show typical symptoms. Genetic, hormonal, and behavioral mechanisms have been proposed to explain sex differences in dementia prevalence. However, whether sex differences
Externí odkaz:
https://doaj.org/article/cfeffadba71e47dda0c649b6a213ba89
Autor:
Roman Hillje, Lucilla Luzi, Stefano Amatori, Giuseppe Persico, Francesca Casciaro, Martina Rusin, Mirco Fanelli, Piergiuseppe Pelicci, Marco Giorgio
Publikováno v:
Aging. 14:4959-4975
To detect the epigenetic drift of time passing, we determined the genome-wide distributions of mono- and tri-methylated lysine 4 and acetylated and tri-methylated lysine 27 of histone H3 in the livers of healthy 3, 6 and 12 months old C57BL/6 mice. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83f6d907a11055b1cab4bcba9917ebbb
https://doi.org/10.18632/aging.204107
https://doi.org/10.18632/aging.204107