Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Giuseppe Manfré"'
Autor:
Giuseppe Manfré, Arianna Novati, Ilaria Faccini, Andrea C Rossetti, Kari Bosch, Raffaella Molteni, Marco A Riva, Johanneke E Van der Harst, Huu Phuc Nguyen, Judith R Homberg
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192289 (2018)
BACKGROUND:Huntington disease (HD) is a devastating inherited neurodegenerative disorder characterized by progressive motor, cognitive, and psychiatric symptoms without any cure to slow down or stop the progress of the disease. The BACHD rat model fo
Externí odkaz:
https://doaj.org/article/7d1dde89d98946568d562c0ea895bf4e
Autor:
Reinaldo Espindola, Venanzio Vella, Natividad Benito, Isabel Mur, Sara Tedeschi, Nicolò Rossi, Johannes G.E. Hendriks, Luisa Sorlí, Oscar Murillo, Mathew Scarborough, Claire Scarborough, Jan Kluytmans, Mateo Carlo Ferrari, Mathias W. Pletz, Iain Mcnamara, Rosa Escudero-Sanchez, Cedric Arvieux, Cecile Batailler, Frédéric-Antoine Dauchy, Wai-Yan Liu, Jaime Lora-Tamayo, Julia Praena, Andrew Ustianowski, Elisa Cinconze, Michele Pellegrini, Fabio Bagnoli, Jesús Rodríguez-Baño, Maria Dolores Del Toro, Nienke Cuperus, Giuseppe Manfré, Eleonora Zamparini, Stéphanie Verhagen, Juan P. Horcajada, Joan Gómez Junyent, Albert Alier, Laura Soldevila, Miranda van Rijen, Jannie Romme, Juliane Ankert, Celia Whitehouse, Adrian Jones, Javier Cobo, Javier Moreno, Anne Meheut, Claire Gledel, Pauline Perreau, Remco J.A. van Wensen, Gabriella Lindergard
[Objectives] We aim to identify the preoperative and perioperative risk factors associated with post-surgical Staphylococcus aureus prosthetic joint infections (PJI) and to develop and validate risk-scoring systems, to allow a better identification o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::117413b42d035c89927bf58370727a54
http://hdl.handle.net/10261/307239
http://hdl.handle.net/10261/307239
Autor:
Giuseppe Manfré, Erik K. H. Clemensson, Elisavet I. Kyriakou, Laura E. Clemensson, Johanneke E. van der Harst, Judith R. Homberg, Huu Phuc Nguyen
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 11 (2017)
Rationale: Huntington disease (HD) is a progressive neurodegenerative disorder characterized by motor, cognitive and neuropsychiatric symptoms. HD is usually diagnosed by the appearance of motor deficits, resulting in skilled hand use disruption, gai
Externí odkaz:
https://doaj.org/article/90bc0acc49f648deb6cc9a4e9edbf356
Autor:
Johanneke E. Van der Harst, Robert Wronski, Judith R. Homberg, Huu Phuc Nguyen, Giuseppe Manfré, Arianna Novati, Stefanie Flunkert
Publikováno v:
Behavioural Brain Research, 393
Behavioural Brain Research
Behavioural Brain Research
Huntington disease (HD) is a neurodegenerative disorder caused by a polyglutamine expansion in the HTT gene. Various HD animal models have been generated to mimic the motor, cognitive and neuropsychiatric disturbances that affect HD patients. Reprodu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c371df903abd16fd74f30e40af6397
http://hdl.handle.net/2066/221717
http://hdl.handle.net/2066/221717
Autor:
Arianna Novati, Huu Phuc Nguyen, Judith R. Homberg, Giuseppe Manfré, Ilaria Faccini, Johanneke E. Van der Harst
Publikováno v:
Models for HD.
Background Social behavior related symptoms and sexual disturbances are frequently reported in Huntington disease (HD) patients, but scarcely studied in animal models. The BACHD rat model for HD carries the human full length mutated HTT with 97 CAG-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9218050a5907b8b6729902e0da63e81
https://doi.org/10.1136/jnnp-2018-ehdn.58
https://doi.org/10.1136/jnnp-2018-ehdn.58
Autor:
Christina Isaksson, Erika Elgstrand Wettergren, Cecilia Lundberg, Giuseppe Manfré, Luis Quintino, Angrit Namislo
Publikováno v:
Molecular Therapy. 21:2169-2180
Glial cell line-derived neurotrophic factor (GDNF) has great potential to treat Parkinson's disease (PD). However, constitutive expression of GDNF can over time lead to side effects. Therefore, it would be useful to regulate GDNF expression. Recently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39daf395cc05864ae672a4edfc0c53f2
https://doi.org/10.1038/mt.2013.169
https://doi.org/10.1038/mt.2013.169
Autor:
Huu Phuc Nguyen, Judith R. Homberg, Giuseppe Manfré, Jesús A. Spadaro, Elisavet I. Kyriakou, Johanneke E. Van der Harst
Publikováno v:
Behavioural Brain Research, 321, 106-112
Behavioural Brain Research, 321, pp. 106-112
Behavioural Brain Research, 321, pp. 106-112
Contains fulltext : 169896.pdf (Publisher’s version ) (Closed access) Anxiety as a common feature of several neurodegenerative/polyglutamine diseases is an important aspect for the face validity of an animal model for Spinocerebellar Ataxia type 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc915be75645b4921ab5b933f25cf24
https://pubmed.ncbi.nlm.nih.gov/28017852
https://pubmed.ncbi.nlm.nih.gov/28017852
Autor:
Kari Bosch, Raffaella Molteni, Johanneke E. Van der Harst, Judith R. Homberg, Andrea C. Rossetti, Giuseppe Manfré, Ilaria Faccini, Marco A. Riva, Huu Phuc Nguyen, Arianna Novati
Publikováno v:
PLoS One, 13
PLoS ONE, Vol 13, Iss 2, p e0192289 (2018)
PLoS ONE
PLoS One, 13, 2
PLoS ONE, Vol 13, Iss 2, p e0192289 (2018)
PLoS ONE
PLoS One, 13, 2
Background Huntington disease (HD) is a devastating inherited neurodegenerative disorder characterized by progressive motor, cognitive, and psychiatric symptoms without any cure to slow down or stop the progress of the disease. The BACHD rat model fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3facc8c4de076d80fc17877425f43a57
https://doi.org/10.1371/journal.pone.0192289
https://doi.org/10.1371/journal.pone.0192289
Autor:
Nicole El Massioui, Huu Phuc Nguyen, Olaf Riess, Giuseppe Manfré, Simon Bossi, Valérie Doyère
Publikováno v:
Behavioural Brain Research
Behavioural Brain Research, Elsevier, 2015, 299, pp.6-10. ⟨10.1016/j.bbr.2015.11.007⟩
Behavioural Brain Research, Elsevier, 2015, 299, pp.6-10. ⟨10.1016/j.bbr.2015.11.007⟩
International audience; Impulsivity trait was characterized in 3-5 months old BACHD rats, a transgenic model of Huntington disease, using (1) the delay discounting task to assess cognitive/choice impulsivity, and (2) the Differential Reinforcement of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd9798d1afc081a08f68616f834bae3f
https://hal.archives-ouvertes.fr/hal-01240379
https://hal.archives-ouvertes.fr/hal-01240379
Publikováno v:
Neuromethods ISBN: 9781627036092
Gene therapy is a promising future tool for treatment of Parkinson’s disease (PD) and several different strategies are currently being evaluated. Although many of these strategies have shown promising results in animal models of PD and parkinsonian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61af620c97bfa7f7c35a3c9e39a000e3
https://doi.org/10.1007/978-1-62703-610-8_10
https://doi.org/10.1007/978-1-62703-610-8_10