Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Giuseppe Lungarella"'
Publikováno v:
Journal of Inflammation, Vol 17, Iss 1, Pp 1-8 (2020)
Abstract The current pandemic of COVID-19 has caused severe morbidity and mortality across the globe. People with a smoking history have severe disease outcomes by COVID-19 infection. Epidemiological studies show that old age and pre-existing disease
Externí odkaz:
https://doaj.org/article/1ce5c5c4d33a49018cd9213acd927e57
Autor:
Giovanna De Cunto, Simone De Meo, Barbara Bartalesi, Eleonora Cavarra, Giuseppe Lungarella, Monica Lucattelli
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 9104 (2022)
Once COPD is established, pulmonary lesions can only progress and smoking cessation by itself is not sufficient to switch off persistent lung inflammation. Similarly, in former-smoker mice, neutrophil inflammation persists and lung lesions undergo pr
Externí odkaz:
https://doaj.org/article/e7074031a0ba4222adff921ca15ae6b1
Autor:
Elena Dozio, Simone Vettoretti, Giuseppe Lungarella, Piergiorgio Messa, Massimiliano M. Corsi Romanelli
Publikováno v:
Biomedicines, Vol 9, Iss 4, p 405 (2021)
Sarcopenia is common in chronic kidney disease (CKD), and it is independently associated with morbidity and mortality. Advanced glycation end products (AGE) are mainly known as aging products. In CKD, AGE accumulate due to increased production and re
Externí odkaz:
https://doaj.org/article/673c34d354054f1c9ead74abf5099331
Autor:
Elisa Trevisan, Giuliano Zabucchi, Lorella Pascolo, Ernesto Pascotto, Claudia Casarsa, Monica Lucattelli, Giuseppe Lungarella, Eleonora Cavarra, Barbara Bartalesi, Marina Zweyer, Violetta Borelli
Publikováno v:
Data in Brief, Vol 6, Iss , Pp 769-775 (2016)
This data article contains data related to the research article entitled, “Synchrotron X-ray microscopy reveals early calcium and iron interaction with crocidolite fibers in the lung of exposed mice” [1]. Asbestos fibers disrupt iron homeostasis
Externí odkaz:
https://doaj.org/article/cbeaeb188bb2493c914b399e87c9575b
Autor:
Marco A. Sutter, Tiziana P. Cremona, Izabela Nita, Eleonora Cavarra, Giuseppe Lungarella, Eli C. Lewis, Johannes C. Schittny, Thomas Geiser, Amiq Gazdhar
Publikováno v:
Pharmaceutics, Vol 12, Iss 9, p 793 (2020)
Rationale: Mutation in the alpha1 antitrypsin (AAT) gene leads to low circulating levels of AAT, which is associated with several disease processes including pulmonary emphysema. The standard of care relies on substitution with plasma-purified AAT. W
Externí odkaz:
https://doaj.org/article/7e02e3d291bc4b8e8e09e6a0b265e311
Autor:
Tobias Müller, Susanne Fay, Rodolfo Paula Vieira, Harry Karmouty-Quintana, Sanja Cicko, Cemil Korcan Ayata, Gernot Zissel, Torsten Goldmann, Giuseppe Lungarella, Davide Ferrari, Francesco Di Virgilio, Bernard Robaye, Jean-Marie Boeynaems, Eduardo R. Lazarowski, Michael R. Blackburn, Marco Idzko
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Idiopathic pulmonary fibrosis (IPF) is a disease with a poor prognosis and very few available treatment options. The involvement of the purinergic receptor subtypes P2Y2 and P2X7 in fibrotic lung disease has been demonstrated recently. In this study,
Externí odkaz:
https://doaj.org/article/5d30d0b580534cbfbfb47bc665ed4a96
Autor:
Giovanna De Cunto, Arianna Lamberti, Maria Margherita de Santi, Clelia Miracco, Michele Fimiani, Giuseppe Lungarella, Eleonora Cavarra
Publikováno v:
Mediators of Inflammation, Vol 2017 (2017)
Little is known about the cause and pathophysiology of middermal elastolysis (MDE). In this condition, variable inflammatory infiltrate may be present or not together with loss of elastic fibres in the middermis that spares both papillary and lower r
Externí odkaz:
https://doaj.org/article/038b3b89ad8d4a5cb87b32bf7b377e4c
Autor:
Benedetta Lunghi, Giovanna De Cunto, Eleonora Cavarra, Silvia Fineschi, Barbara Bartalesi, Giuseppe Lungarella, Monica Lucattelli
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119797 (2015)
The adaptor protein p66Shc regulates intracellular oxidant levels through the modulation of a forkhead-related transcription factor (FOXO3a). The genetic ablation of p66Shc (p66Shc-/-) renders mice resistant to oxidative stress and p53-dependent apop
Externí odkaz:
https://doaj.org/article/57aa09445e1a48a8ad9cd991db758905
Autor:
Maria Galluzzo, Elisa Ciraolo, Monica Lucattelli, Eriola Hoxha, Martina Ulrich, Carlo Cosimo Campa, Giuseppe Lungarella, Gerd Doring, Zhe Zhou-Suckow, Marcus Mall, Emilio Hirsch, Virginia De Rose
Publikováno v:
Mediators of Inflammation, Vol 2015 (2015)
Purpose. Neutrophil-dominated airway inflammation is a key feature of progressive lung damage in cystic fibrosis (CF). Thus, reducing airway inflammation is a major goal to prevent lung damage in CF. However, current anti-inflammatory drugs have show
Externí odkaz:
https://doaj.org/article/10e9eed7de0345ceb9e15ae2ed246132
Autor:
Michelangelo Di Giuseppe, Federica Gambelli, Gary W Hoyle, Giuseppe Lungarella, Sean M Studer, Thomas Richards, Sam Yousem, Ken McCurry, James Dauber, Naftali Kaminski, George Leikauf, Luis A Ortiz
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5689 (2009)
Silicosis is a complex lung disease for which no successful treatment is available and therefore lung transplantation is a potential alternative. Tumor necrosis factor alpha (TNFalpha) plays a central role in the pathogenesis of silicosis. TNFalpha s
Externí odkaz:
https://doaj.org/article/c90d34fb100d41e69478640c605ad1b2