Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Giuseppe Lofano"'
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-15 (2021)
Abstract Emulsion adjuvants such as MF59 and AS03 have been used for more than two decades as key components of licensed vaccines, with over 100 million doses administered to diverse populations in more than 30 countries. Substantial clinical experie
Externí odkaz:
https://doaj.org/article/75d1380960444ee990bb5e69e49dc32a
Autor:
Gianluca Selvaggio, Lorena Leonardelli, Giuseppe Lofano, Stephanie Fresnay, Silvia Parolo, Duccio Medini, Emilio Siena, Luca Marchetti
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 12, Pp 1448-1451 (2021)
Externí odkaz:
https://doaj.org/article/e8b21ffcef0c4ca4a2f9265f9caae9a9
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/e5f8067830144b07ac2835d863125981
Autor:
Lorena Leonardelli, Giuseppe Lofano, Gianluca Selvaggio, Silvia Parolo, Stefano Giampiccolo, Danilo Tomasoni, Enrico Domenici, Corrado Priami, Haifeng Song, Duccio Medini, Luca Marchetti, Emilio Siena
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
RNA vaccines represent a milestone in the history of vaccinology. They provide several advantages over more traditional approaches to vaccine development, showing strong immunogenicity and an overall favorable safety profile. While preclinical testin
Externí odkaz:
https://doaj.org/article/2339446d667e4c499e4d3df6c6ee4afe
Autor:
Deniz Cizmeci, Giuseppe Lofano, Evan Rossignol, Anne-Sophie Dugast, Dongkyoon Kim, Guy Cavet, Ngan Nguyen, Yann Chong Tan, Michael S Seaman, Galit Alter, Boris Julg
Publikováno v:
eLife, Vol 10 (2021)
A minor subset of individuals infected with HIV-1 develop antibody neutralization breadth during the natural course of the infection, often linked to chronic, high-level viremia. Despite significant efforts, vaccination strategies have been unable to
Externí odkaz:
https://doaj.org/article/742b0119745f4f6ba978c07e113f3df9
Autor:
Rasmus Offersen, Wen-Han Yu, Eileen P. Scully, Boris Julg, Zelda Euler, Saheli Sadanand, Dario Garcia-Dominguez, Lu Zheng, Thomas A. Rasmussen, Madeleine F. Jennewein, Caitlyn Linde, Jessica Sassic, Giuseppe Lofano, Selena Vigano, Kathryn E. Stephenson, Stephanie Fischinger, Todd J. Suscovich, Mathias Lichterfeld, Douglas Lauffenburger, Erik S. Rosenberg, Todd Allen, Marcus Altfeld, Richelle C. Charles, Lars Østergaard, Martin Tolstrup, Dan H. Barouch, Ole S. Søgaard, Galit Alter
Publikováno v:
Cell Reports, Vol 33, Iss 11, Pp 108502- (2020)
Summary: Changes in antibody glycosylation are linked to inflammation across several diseases. Alterations in bulk antibody galactosylation can predict rheumatic flares, act as a sensor for immune activation, predict gastric cancer relapse, track wit
Externí odkaz:
https://doaj.org/article/708b5101342c4ee5a05e68d73b2077b4
Autor:
Francesca Mancini, Elisabetta Monaci, Giuseppe Lofano, Antonina Torre, Marta Bacconi, Simona Tavarini, Chiara Sammicheli, Letizia Arcidiacono, Bruno Galletti, Donatello Laera, Michele Pallaoro, Giovanna Tuscano, Maria Rita Fontana, Giuliano Bensi, Guido Grandi, Silvia Rossi-Paccani, Sandra Nuti, Rino Rappuoli, Ennio De Gregorio, Fabio Bagnoli, Elisabetta Soldaini, Sylvie Bertholet
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147767 (2016)
A rapidly acting, single dose vaccine against Staphylococcus aureus would be highly beneficial for patients scheduled for major surgeries or in intensive care units. Here we show that one immunization with a multicomponent S. aureus candidate vaccine
Externí odkaz:
https://doaj.org/article/6ab3e96e44b344fa8ee5845c6760ebd9
Autor:
Giulietta Maruggi, Corey P. Mallett, Jason W. Westerbeck, Tiffany Chen, Giuseppe Lofano, Kristian Friedrich, Lin Qu, Jennifer Tong Sun, Josie McAuliffe, Amey Kanitkar, Kathryn T. Arrildt, Kai-Fen Wang, Ian McBee, Deborah McCoy, Rebecca Terry, Alison Rowles, Maia Araujo Abrahim, Michael A. Ringenberg, Malcolm J. Gains, Catherine Spickler, Xuping Xie, Jing Zou, Pei-Yong Shi, Taru Dutt, Marcela Henao-Tamayo, Izabela Ragan, Richard A. Bowen, Russell Johnson, Sandra Nuti, Kate Luisi, Jeffrey B. Ulmer, Ann-Muriel Steff, Rashmi Jalah, Sylvie Bertholet, Alan H. Stokes, Dong Yu
Publikováno v:
Molecular Therapy
RNA vaccines have demonstrated efficacy against SARS-CoV-2 in humans and the technology, is being leveraged for rapid emergency response. In this report, we assessed immunogenicity, and, for the first time, toxicity, biodistribution and protective ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f8ac8597c1bbd871ec96b10ef6faf90
https://doi.org/10.1016/j.ymthe.2022.01.001
https://doi.org/10.1016/j.ymthe.2022.01.001
Autor:
Silivia Parolo, Stephanie Fresnay, Gianluca Selvaggio, Giuseppe Lofano, Duccio Medini, Luca Marchetti, Lorena Leonardelli, Emilio Siena
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 12, Pp 1448-1451 (2021)
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 12, Pp 1448-1451 (2021)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09804b92c504869a816f9cf229a1c69e
http://europepmc.org/articles/PMC8674002
http://europepmc.org/articles/PMC8674002
Publikováno v:
npj Vaccines, Vol 5, Iss 1, Pp 1-13 (2020)
npj Vaccines
NPJ Vaccines
npj Vaccines
NPJ Vaccines
Vaccines represent the most successful medical intervention in history, with billions of lives saved. Although multiple doses of the same vaccine are typically required to reach an adequate level of protection, it would be advantageous to develop vac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::263a882563993d13f0a4256ed5be219e
http://link.springer.com/article/10.1038/s41541-020-00238-8
http://link.springer.com/article/10.1038/s41541-020-00238-8