Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Giuseppe Infusini"'
Physiological substrates and ontogeny-specific expression of the ubiquitin ligases MARCH1 and MARCH8
Autor:
Patrick Schriek, Haiyin Liu, Alan C. Ching, Pauline Huang, Nishma Gupta, Kayla R. Wilson, MinHsuang Tsai, Yuting Yan, Christophe F. Macri, Laura F. Dagley, Giuseppe Infusini, Andrew I. Webb, Hamish E.G. McWilliam, Satoshi Ishido, Justine D. Mintern, Jose A. Villadangos
Publikováno v:
Current Research in Immunology, Vol 2, Iss , Pp 218-228 (2021)
MARCH1 and MARCH8 are ubiquitin ligases that control the expression and trafficking of critical immunoreceptors. Understanding of their function is hampered by three major knowledge gaps: (i) it is unclear which cell types utilize these ligases; (ii)
Externí odkaz:
https://doaj.org/article/6a717133d4e94e62b63aa75cdf8d87bd
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0271025 (2022)
For bottom-up proteomic analysis, the goal of analytical pipelines that process the raw output of mass spectrometers is to detect, characterise, identify, and quantify peptides. The initial steps of detecting and characterising features in raw data m
Externí odkaz:
https://doaj.org/article/63d9ee5d4b6a44eeb133fffb910e03d0
Autor:
James G. Bedford, Giuseppe Infusini, Laura F. Dagley, Fernando Villalon-Letelier, Ming Z. M. Zheng, Vicki Bennett-Wood, Patrick C. Reading, Linda M. Wakim
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Exosomes are extracellular vesicles secreted by cells that have an important biological function in intercellular communication by transferring biologically active proteins, lipids, and RNAs to neighboring or distant cells. While a role for exosomes
Externí odkaz:
https://doaj.org/article/43fe2ee02266451a9a1080a0a25add41
Autor:
Michael J. Coffey, Laura F. Dagley, Simona Seizova, Eugene A. Kapp, Giuseppe Infusini, David S. Roos, Justin A. Boddey, Andrew I. Webb, Christopher J. Tonkin
Publikováno v:
mBio, Vol 9, Iss 5 (2018)
ABSTRACT Toxoplasma gondii infects approximately 30% of the world’s population, causing disease primarily during pregnancy and in individuals with weakened immune systems. Toxoplasma secretes and exports effector proteins that modulate the host dur
Externí odkaz:
https://doaj.org/article/ea7a3291199047328178731b63d09cfa
Autor:
Lukasz Kedzierski, Michelle D Tate, Alan C Hsu, Tatiana B Kolesnik, Edmond M Linossi, Laura Dagley, Zhaoguang Dong, Sarah Freeman, Giuseppe Infusini, Malcolm R Starkey, Nicola L Bird, Simon M Chatfield, Jeffrey J Babon, Nicholas Huntington, Gabrielle Belz, Andrew Webb, Peter AB Wark, Nicos A Nicola, Jianqing Xu, Katherine Kedzierska, Philip M Hansbro, Sandra E Nicholson
Publikováno v:
eLife, Vol 6 (2017)
Influenza virus infections have a significant impact on global human health. Individuals with suppressed immunity, or suffering from chronic inflammatory conditions such as COPD, are particularly susceptible to influenza. Here we show that suppressor
Externí odkaz:
https://doaj.org/article/1e6a3080baa04d2a86774d6d71b6e598
Autor:
Giuseppe Infusini, Jeffrey M Smith, He Yuan, Angela Pizzolla, Wy Ching Ng, Sarah L Londrigan, Ashraful Haque, Patrick C Reading, Jose A Villadangos, Linda M Wakim
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143539 (2015)
Respiratory dendritic cells (DC) play a pivotal role in the initiation of adaptive immune responses to influenza virus. To do this, respiratory DCs must ferry viral antigen from the lung to the draining lymph node without becoming infected and perish
Externí odkaz:
https://doaj.org/article/e281a09743104989bec7053a0ed1ca15
Autor:
Anna Quaglieri, Joseph Bloom, Aaron Triantafyllidis, Bradley Green, Mark R. Condina, Paula Burton Ngov, Giuseppe Infusini, Andrew I. Webb
Data processing is essential to reliably generate knowledge from proteomics studies. The complexity of the proteomics data, as well as the ability of research teams to adopt complex analysis pipelines, have proven to be an obstacle to effective colla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::572dcef0df1eff7c7e172666a6250b56
https://doi.org/10.1101/2022.12.12.517480
https://doi.org/10.1101/2022.12.12.517480
Physiological substrates and ontogeny-specific expression of the ubiquitin ligases MARCH1 and MARCH8
Autor:
Justine D. Mintern, Yuting Yan, Kayla R. Wilson, Pauline Huang, Haiyin Liu, Nishma Gupta, Christophe Macri, Patrick Schriek, Laura F. Dagley, Jose A Villadangos, Hamish E G McWilliam, MinHsuang Tsai, Satoshi Ishido, Andrew I. Webb, Alan C. Ching, Giuseppe Infusini
Publikováno v:
Current Research in Immunology, Vol 2, Iss, Pp 218-228 (2021)
MARCH1 and MARCH8 are ubiquitin ligases that control the expression and trafficking of critical immunoreceptors. Understanding of their function is hampered by three major knowledge gaps: (i) it is unclear which cell types utilize these ligases; (ii)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::873b6947ee55bea1d512ee87ee7bdbaa
http://www.sciencedirect.com/science/article/pii/S2590255521000214
http://www.sciencedirect.com/science/article/pii/S2590255521000214
1AbstractThe determination of relative protein abundance in label-free data dependant acquisition (DDA) LC-MS/MS proteomics experiments is hindered by the stochastic nature of peptide detection and identification. Peptides with an abundance near the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c18b4bb2e4e33742dbc60540be838b2
https://doi.org/10.1101/2022.04.25.489464
https://doi.org/10.1101/2022.04.25.489464
1AbstractFor bottom-up proteomic analysis, the goal of analytical pipelines that process the raw output of mass spectrometers is to detect, characterise, identify, and quantify peptides. The initial steps of detecting and characterising features in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dedc9a17497876548229ca8e6b80165
https://doi.org/10.1101/2021.10.18.464737
https://doi.org/10.1101/2021.10.18.464737