Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Giuseppe Fasolino"'
Publikováno v:
BMC Ophthalmology, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background The use of immunomodulating therapy to treat various cancers has been on the rise and these immune checkpoint inhibitors are known to cause ocular side effects. In this article a case of acute exudative polymorphous vitelliform ma
Externí odkaz:
https://doaj.org/article/86a8729adb1c447a9359c94b467b5dcc
Autor:
Giuseppe Fasolino, Laura Moschetta, Jacques De Grève, Pieter Nelis, Pierre Lefesvre, Marcel Ten Tusscher
Publikováno v:
Diagnostics, Vol 12, Iss 2, p 249 (2022)
Emerging anticancer agents such as the pan-FGFR Inhibitor have achieved remarkable improvements in the survival of patients with metastatic malignancies. Nevertheless they are still associated with specific ophthalmic toxicities. Understanding their
Externí odkaz:
https://doaj.org/article/de6ae85d75ab478d88511d550245aca3
Autor:
Gil Awada, Julia Katharina Schwarze, Jens Tijtgat, Giuseppe Fasolino, Vibeke Kruse, Bart Neyns
Publikováno v:
Melanoma research
Patients with advanced v-Raf murine sarcoma viral oncogene homolog B V600 (BRAFV600) mutant melanoma who progressed on prior treatment with v-Raf murine sarcoma viral oncogene homolog B (BRAF)/mitogen-activated protein kinase kinase (MEK) inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::236a54e9f821e576ac0b4c470c075658
https://doi.org/10.1097/cmr.0000000000000821
https://doi.org/10.1097/cmr.0000000000000821
Autor:
Jorgos Koulalis, Robert W Kuijpers, Marcel P. M. ten Tusscher, Pieter Nelis, Giuseppe Fasolino, Bart Neyns, Gil Awada, Peter Van Elderen
Publikováno v:
Seminars in Ophthalmology. 36:765-771
PURPOSE: The present study investigates by optical coherence tomography angiography (OCTA) the retinal capillary plexus and choriocapillaris flow voids and their possible correlation with MEKAR. METHODS: 34 eyes of 17 patients (61.5 years [30.4-77.4]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9971cc3ec427f247ef8cc8e8b14ddbe3
https://doi.org/10.1080/08820538.2021.1903512
https://doi.org/10.1080/08820538.2021.1903512
Autor:
Giuseppe Fasolino, Gil Awada, Laura Moschetta, Jorgos Socrates Koulalis, Bart Neyns, Bert Verhelst, Peter Van Elderen, Pieter Nelis, Paul Cardon de Lichtbuer, Wilfried Cools, Marcellinus Ten Tusscher
Publikováno v:
Journal of Clinical Medicine
Volume 12
Issue 3
Pages: 1214
Volume 12
Issue 3
Pages: 1214
In the last two decades, an increasing number of so-called molecular-targeted therapies have become available for the treatment of patients with advanced malignancies. These drugs have included inhibitors of proteins in the MAPK pathway, such as BRAF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b89dfea010c0b1e4f895943b0fa8457
https://doi.org/10.3390/jcm12031214
https://doi.org/10.3390/jcm12031214
Publikováno v:
BMJ Case Reports
We present a case of non-arteritic anterior ischaemic optic neuropathy (NAION) with no ocular or systemic risk factors in a patient who recovered from a recent SARS-CoV-2 pneumonia. NAION is the most common acute optic neuropathy among individuals ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3108eb17b3214755ac2f2185ca27ea9c
https://pubmed.ncbi.nlm.nih.gov/34281937
https://pubmed.ncbi.nlm.nih.gov/34281937
Autor:
Marcel P. M. ten Tusscher, Giuseppe Fasolino, Robert W A M Kuijpers, Bart Neyns, Ine Lambert, Gil Awada
Publikováno v:
BMC Ophthalmology
BMC Ophthalmology, Vol 21, Iss 1, Pp 1-8 (2021)
BMC Ophthalmology, Vol 21, Iss 1, Pp 1-8 (2021)
Background The use of immunomodulating therapy to treat various cancers has been on the rise and these immune checkpoint inhibitors are known to cause ocular side effects. In this article a case of acute exudative polymorphous vitelliform maculopathy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca6441a2025b72c30d97f80b0831cd0d
https://doi.org/10.1186/s12886-021-02011-4
https://doi.org/10.1186/s12886-021-02011-4
Autor:
Gil Awada, Hendrik Everaert, Julia Katharina Schwarze, Jens Tijtgat, Giuseppe Fasolino, Bart Neyns
Publikováno v:
Cancers
Volume 13
Issue 9
Cancers, Vol 13, Iss 2010, p 2010 (2021)
Volume 13
Issue 9
Cancers, Vol 13, Iss 2010, p 2010 (2021)
Simple Summary MEK-inhibitor monotherapy has activity in advanced NRASQ61R/K/L mutant melanoma but is associated with dose-limiting cutaneous toxicity. The combination of a BRAF- with a MEK-inhibitor at their full dose (as in BRAFV600E/K mutant melan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::099669cabf5c3ef996bb2951be2842c6
Autor:
Gil Awada, Julia Katharina Schwarze, Eva Reijmen, Cleo Goyvaerts, Giuseppe Fasolino, sandrine aspeslagh, Bart Neyns
Publikováno v:
Vrije Universiteit Brussel
Background: Preclinical and clinical data suggest MEK-inhibition (MEKi) to be effective in NRAS-mutant (mt) and NRAS wild-type (wt) melanoma. However, MEKi causes considerable cutaneous treatment-related adverse events (TRAE) which are less present i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::53338b0a6318977da032412bb2b71ab1
https://biblio.vub.ac.be/vubir/interim-safety-and-efficacy-results-of-a-phase-ii-clinical-trial-on-trametinib-and-lowdose-dabrafenib-in-patients-with-advanced-brafv600-wildtype-melanoma(19b30e2a-aed0-4c7c-8591-653b86a4b31c).html
https://biblio.vub.ac.be/vubir/interim-safety-and-efficacy-results-of-a-phase-ii-clinical-trial-on-trametinib-and-lowdose-dabrafenib-in-patients-with-advanced-brafv600-wildtype-melanoma(19b30e2a-aed0-4c7c-8591-653b86a4b31c).html
Autor:
Bart Neyns, Hendrik Everaert, Gil Awada, Giuseppe Fasolino, Julia Katharina Schwarze, Jens Tijtgat
Publikováno v:
Journal of Clinical Oncology. 39:9529-9529
9529 Background: The mitogen-activated protein kinase (MAPK) pathway can be activated by alternative driver mutations in BRAFV600/ NRASQ61R/K/L wild-type (wt) melanoma. MEK-inhibitor monotherapy has activity in BRAFV600/ NRASQ61R/K/L wt melanoma, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc9230f964ac006ddeb1738221e4b31
https://doi.org/10.1200/jco.2021.39.15_suppl.9529
https://doi.org/10.1200/jco.2021.39.15_suppl.9529