Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Giuseppe Coppotelli"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 3, Pp 1987-2026 (2024)
Mitochondria are thought to have become incorporated within the eukaryotic cell approximately 2 billion years ago and play a role in a variety of cellular processes, such as energy production, calcium buffering and homeostasis, steroid synthesis, cel
Externí odkaz:
https://doaj.org/article/c1c6dcb947854899be318638f19194c7
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
Incidence of anxiety-like disorders in humans has been shown to decrease with aging; however, it is still under debate whether there are similarities in mice, which would support the use of mouse models in understanding the neuronal network changes t
Externí odkaz:
https://doaj.org/article/b57f8d71341741bc9c6cbef460cc30b6
Publikováno v:
Biomolecules, Vol 14, Iss 2, p 162 (2024)
Mitochondrial dysfunction has been implicated in aging and age-related disorders. Disturbed-protein homeostasis and clearance of damaged proteins have also been linked to aging, as well as to neurodegenerative diseases, cancers, and metabolic disorde
Externí odkaz:
https://doaj.org/article/8369cf37df9e45438547dec7bc19a5fb
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12308 (2023)
Environmental pollutants have become quite ubiquitous over the past two centuries; of those, plastics, and in particular, microplastics (
Externí odkaz:
https://doaj.org/article/b579cb1386f44c4b9e4125b71c3e4344
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10359 (2023)
The past several decades has seen a huge expansion of the knowledge and research of mitochondrial dysfunction and the role it plays in ageing and age-related diseases [...]
Externí odkaz:
https://doaj.org/article/370a5f6fb47e4a47942a53c5cb751e74
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 8, Pp 19458-19476 (2015)
Mitochondrial dysfunction and impairment of the ubiquitin proteasome system have been described as two hallmarks of the ageing process. Additionally, both systems have been implicated in the etiopathogenesis of many age-related diseases, particularly
Externí odkaz:
https://doaj.org/article/144968ad2c464528a99d670acaba7989
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62783 (2013)
The capacity of gamma-herpesviruses to establish lifelong infections is dependent on the expression of genome maintenance proteins (GMPs) that tether the viral episomes to cellular chromatin and allow their persistence in latently infected proliferat
Externí odkaz:
https://doaj.org/article/96285ff024c34565ba97f20c1608a929
Autor:
Giuseppe Coppotelli, Jaime M. Ross
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 5, p 711 (2016)
The past decade has witnessed an explosion of knowledge regarding how mitochondrial dysfunction may translate into ageing and disease phenotypes, as well as how it is modulated by genetic and lifestyle factors.[...]
Externí odkaz:
https://doaj.org/article/28a43ac93f3c499696108632d104b8b4
Autor:
Ximena Cortes-Bratti, Eugénie Bassères, Fabiola Herrera-Rodriguez, Silvia Botero-Kleiven, Giuseppe Coppotelli, Jens B Andersen, Maria G Masucci, Arne Holmgren, Esteban Chaves-Olarte, Teresa Frisan, Javier Avila-Cariño
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16960 (2011)
BackgroundThioredoxin 80 (Trx80) is an 80 amino acid natural cleavage product of Trx, produced primarily by monocytes. Trx80 induces differentiation of human monocytes into a novel cell type, named Trx80-activated-monocytes (TAMs).Principal findingsI
Externí odkaz:
https://doaj.org/article/a3a2c7311ab8442e9881fec7e662edd7
Autor:
Jae-Hyun Yang, Motoshi Hayano, Patrick T. Griffin, João A. Amorim, Michael S. Bonkowski, John K. Apostolides, Elias L. Salfati, Marco Blanchette, Elizabeth M. Munding, Mital Bhakta, Yap Ching Chew, Wei Guo, Xiaojing Yang, Sun Maybury-Lewis, Xiao Tian, Jaime M. Ross, Giuseppe Coppotelli, Margarita V. Meer, Ryan Rogers-Hammond, Daniel L. Vera, Yuancheng Ryan Lu, Jeffrey W. Pippin, Michael L. Creswell, Zhixun Dou, Caiyue Xu, Sarah J. Mitchell, Abhirup Das, Brendan L. O’Connell, Sachin Thakur, Alice E. Kane, Qiao Su, Yasuaki Mohri, Emi K. Nishimura, Laura Schaevitz, Neha Garg, Ana-Maria Balta, Meghan A. Rego, Meredith Gregory-Ksander, Tatjana C. Jakobs, Lei Zhong, Hiroko Wakimoto, Jihad El Andari, Dirk Grimm, Raul Mostoslavsky, Amy J. Wagers, Kazuo Tsubota, Stephen J. Bonasera, Carlos M. Palmeira, Jonathan G. Seidman, Christine E. Seidman, Norman S. Wolf, Jill A. Kreiling, John M. Sedivy, George F. Murphy, Richard E. Green, Benjamin A. Garcia, Shelley L. Berger, Philipp Oberdoerffer, Stuart J. Shankland, Vadim N. Gladyshev, Bruce R. Ksander, Andreas R. Pfenning, Luis A. Rajman, David A. Sinclair
Publikováno v:
Cell. 186:305-326.e27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a40d556fd25f6db5d4a9f1a0234305aa
https://doi.org/10.1016/j.cell.2022.12.027
https://doi.org/10.1016/j.cell.2022.12.027