Výsledky vyhledávání - "Giuseppe Consogno"

Identification of Novel Subdominant Epitopes on the Carcinoembryonic Antigen Recognized by CD4+ T Cells of Lung Cancer Patients

Autor: Giuseppe Consogno, Renato Longhi, Maria Pia Protti, Piero Zannini, Giulio Melloni, Mariacristina Crosti

Publikováno v: 176 (2006): 5093–5099.
info:cnr-pdr/source/autori:Crosti M., Longhi R., Consogno G., Melloni G., Zannini P., Protti M.P./titolo:Identification of novel subdominant epitopes on the carcinoembryonic antigen recognized by CD4(+) T cells of lung cancer patients/doi:/rivista:/anno:2006/pagina_da:5093/pagina_a:5099/intervallo_pagine:5093–5099/volume:176

The carcinoembryonic Ag (CEA) is an attractive target for immunotherapy because of its expression profile and role in tumor progression. To verify the existence of spontaneous anti-CEA CD4+ T cells in lung cancer patients, we first identified CEA seq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef2e12f0cd34dcab48e4b12dfdbeec9
https://doi.org/10.4049/jimmunol.176.8.5093

Zobrazit plný text záznamu

Increased interleukin-10 serum levels in patients with solid tumours

Autor: Luca Gianotti, Laura Galli, Marco Braga, Giovanni Citterio, Oreste Gentilini, Marco Foppoli, Giuseppe Consogno, Claudio Fortis

Publikováno v: Cancer Letters. 104:1-5

In 40 out of 99 patients (40.4%) with solid tumours of different tissue, but the same stage (IV), elevated serum levels of interleukin-10 were observed. The mean levels of the cytokine in patients with malignant melanoma (24.3 ng/ml), pancreatic (6.8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ffe4f9e9c16d21c2e3671afa157b963
https://doi.org/10.1016/0304-3835(96)04213-9

Zobrazit plný text záznamu

Serum Levels of Soluble Cell Adhesion Molecules (ICAM-1, VCAM-1, E-Selectin) and of Cytokine TNF-α Increase during Interleukin-2 Therapy

Autor: Eraldo O. Bucci, Ugo Scaglietti, Laura Galli, Paola Matteucci, Giovanni Citterio, Claudio Fortis, Giuseppe Consogno

Publikováno v: Clinical Immunology and Immunopathology. 76:142-147

Circulating levels of soluble intracellular adhesion molecule-1, vascular cell adhesion molecule-1, and E-selectin were measured in 20 advanced cancer patients at different times during recombinant interleukin-2 immunotherapy. The concentration of al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdbf215812801f15955a058f2b8e2038
https://doi.org/10.1006/clin.1995.1108

Zobrazit plný text záznamu

Reversible anergy in circulating lymphocytes of cancer patients during interleukin-2 therapy

Autor: Eraldo Bucci, Giovanni Citterio, Giuseppo Landonio, Claudio Fortis, Emilio Clementi, Giuseppe Consogno

Publikováno v: Cancer Immunology Immunotherapy. 39:167-171

Interleukin-2 plays a crucial role in enhancing the antitumor immune response. Clinical trials, mainly in renal cell carcinoma and melanoma patients, have been carried out with encouraging results. Recent reports demonstrated that interleukin-2 thera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ac33996873f6720c6079b74196d7af
https://doi.org/10.1007/bf01533382

Zobrazit plný text záznamu

CD4(+) T cells from healthy subjects and colon cancer patients recognize a carcinoembryonic antigen-specific immunodominant epitope

Autor: Gabriele, Campi, Mariacristina, Crosti, Giuseppe, Consogno, Valeria, Facchinetti, Bianca M, Conti-Fine, Renato, Longhi, Giulia, Casorati, Paolo, Dellabona, Maria Pia, Protti

Publikováno v: Cancer research. 63(23)

The carcinoembryonic antigen (CEA) is an attractive target for immunotherapeutic purposes because of its expression profile, its role in tumor progression, and its immunogenicity. However, CEA belongs to the CD66 immunoglobulin super-gene family that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d2562cc34cff6330c71aec3ad035b47c
https://pubmed.ncbi.nlm.nih.gov/14679013

Zobrazit plný text záznamu

Identification of immunodominant regions among promiscuous HLA-DR-restricted CD4+ T-cell epitopes on the tumor antigen MAGE-3

Autor: Angela Bachi, Maria Pia Protti, Giuseppe Consogno, Claudio Rugarli, Simona Manici, Catia Traversari, Bianca M. Conti-Fine, Valeria Facchinetti, Juergen Hammer

Publikováno v: Blood. 101(3)

The molecular characterization of the CD4+ T-cell epitope repertoire on human tumor antigens would contribute to both clinical investigation and cancer immunotherapy. In particular, the identification of promiscuous epitopes would be beneficial to a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e0df6e777ec4ea1e7912227a68c63c
https://pubmed.ncbi.nlm.nih.gov/12393675

Zobrazit plný text záznamu

Cytokine secretion associated with the clearance of apoptotic bodies in renal cell carcinoma patients

Autor: A. Borri, Angelo A. Manfredi, Valérie S. Zimmermann, Giuseppe Consogno, Elena Rota Caremoli, Patrizia Rovere, Giovanni Citterio, Attilio Bondanza, Anna Guidetti, Claudio Rugarli

The factors determining the outcome of immunotherapy in metastatic renal cell carcinoma (RCC) patients remain elusive. Macrophages from normal donors that phagocytose apoptotic cells secrete the immunosuppressive cytokine IL-10 in vitro. Conversely,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169062b349e79ed165064eb281010211

Zobrazit plný text záznamu

Human melanoma cells transfected with the B7-2 co-stimulatory molecule induce tumor-specific CD8+ cytotoxic T lymphocytes in vitro

Autor: Simona Manici, Maria Adele Imro, Paolo Dellabona, Maria Pia Protti, Silvia Heltai, Giuseppe Consogno, Matteo Bellone, Claudio Rugarli

Publikováno v: Human gene therapy. 9(9)

Neoplastic cells express tumor-associated antigens, but tumor rejection seldom occurs in vivo. The absence of an effective immune response may be explained by the inability of tumor cells to deliver co-stimulatory signals. Indeed, transfection of eit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715f7282550390094b804eb6f92c9c1e
https://pubmed.ncbi.nlm.nih.gov/9650618

Zobrazit plný text záznamu

Thymopentin modulates Th1 and Th2 cytokine response and host survival in experimental injury

Autor: Giuseppe Consogno, Claudio Fortis, Oreste Gentilini, Valerio Di Carlo, Luca Gianotti, Marco Braga

Objective: To investigate the impact of thymopentin (Thy) on mortality and in vivo cytokine release in an animal model of gut-derived sepsis which includes different combinations of allogeneic blood transfusion (T) and burn injury plus bacterial gava

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7ec0c9081aafe7a728f1285b0b28353

Zobrazit plný text záznamu

Role of interleukin-2 in regulating lymphocyte activation and recirculation

Autor: Giuseppe Di Lucca, Claudio Fortis, C. Besana, Elisabetta Ferrero, Claudio Rugarli, Consuelo Corti, Silvia Heltai, Marco Foppoli, Giuseppe Consogno

Publikováno v: European journal of cancer (Oxford, England : 1990). (3)

TO UNDERSTAND better the immunological reactions primed by interleukin-2 (IL-2) in cancer patients we have investigated the biological effects of systemic rIL-2 on the circulating lymphocytes of cancer patients [ 1, 21. We report here immunological t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715ffa849ce7937f65ac6325ed221c20
https://pubmed.ncbi.nlm.nih.gov/8398350

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání