Výsledky vyhledávání - "Giuseppe Celasco"

Calcium butyrate: Anti-inflammatory effect on experimental colitis in rats and antitumor properties

Autor: Katia Mangano, Giuseppe Celasco, Roberto Di Marco, Angela Milasi, C Aiello, Cinzia Quattrocchi, Luigi Moro

Publikováno v: Biomedical Reports. 2:559-563

Butyric acid is a physiological component of the colonic environment that possesses anti-inflammatory and antitumor properties, among others. However, little is known regarding its effects following direct application on the colonic surface. This stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77ac90ffc019f9c3f720e7a0d220f18a
https://doi.org/10.3892/br.2014.273

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A full conformational characterization of antiandrogen cortexolone-17α-propionate and related compounds through theoretical calculations and nuclear magnetic resonance spectroscopy

Autor: Laura Legnani, Patrizia Ferraboschi, Luigi Moro, Diego Colombo, Giuseppe Celasco, Laura Ragonesi

Publikováno v: Med. Chem. Commun.. 5:904-914

Cortexolone-17α-propionate is a topical antiandrogen under investigation for the treatment of androgen-related skin disorders. A full conformational characterization was realized, in comparison with other steroidal androgens and antiandrogens, by me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea73f446e6b910f30887838ef0e0a497
https://doi.org/10.1039/c4md00049h

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Biological Profile of Cortexolone 17a-Propionate (CB-03-01), a New Topical and Peripherally Selective Androgen Antagonist

Autor: Cinzia Quattrocchi, Patrizia Ferraboschi, L. Bartorelli, Luigi Moro, Roberta Bozzella, Giuseppe Celasco, Ferdinande Nicoletti

Publikováno v: Scopus-Elsevier

The aim of this study was to investigate the antiandrogenic activity of a new monoester of cortexolone, cortexolone 17alpha-propionate (CAS 19608-29-8, CB-03-01). Although the compound displayed a strong local antiandrogenic activity in hamster's fla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ecf327390734e30ea634891a093e486
https://doi.org/10.1055/s-0031-1297043

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Anti-inflammatory and immunomodulatory activities of rifamycin SV

Autor: Mara Gerloni, Mauro Ajani, Caridad Rosette, Seema Patkar, Luigi Moro, Roberta Bozzella, Giuseppe Celasco, Fernando Buendia-Laysa

Publikováno v: International journal of antimicrobial agents. 42(2)

There have been several reports showing convincing evidence for non-bactericidal activities of the rifamycin antibiotics. In particular, the parent compound rifamycin SV has been employed in a limited number of cases to treat rheumatoid arthritis. Mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8731854a6f9f704c1227a12adf1917d
https://pubmed.ncbi.nlm.nih.gov/23756321

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In Vitro Activity and Single-Step Mutational Analysis of Rifamycin SV Tested against Enteropathogens Associated with Traveler's Diarrhea and Clostridium difficile▿

Autor: Giuseppe Celasco, Shannon D. Putnam, Douglas J. Biedenbach, Luigi Moro, Roberta Bozzella, Ronald N. Jones, David J. Farrell

Rifamycin SV is a broad-spectrum, poorly absorbed antimicrobial agent that, when coupled with MMX technology, is being targeted for the oral treatment of traveler's diarrhea (TD) and Clostridium difficile -associated disease (CDAD). Rifamycin SV was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f121dc05ca9d65f39c16a021f687b0dc
https://europepmc.org/articles/PMC3067105/

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Efficacy of Intracolonic Administration of Low-Molecular-Weight Heparin CB-01-05, Compared to Other Low-Molecular-Weight Heparins and Unfractionated Heparin, in Experimentally Induced Colitis in Rat

Autor: Luigi Moro, Roberto Di Marco, Paolo Fagone, Cinzia Quattrocchi, Roberta Bozzella, Giuseppe Celasco, Katia Mangano, C Aiello, Marco Donia

Purpose Parenteral administration of low-molecular-weight heparins (LMWHs) and unfractionated heparin (UFH) resulted effective in improving the symptoms of experimental colitis in rat. Today, there is little information about their activity by intrac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2613e1662910d47d938f1bb5a438210e
http://hdl.handle.net/11695/3567

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Mesoglycan treatment restores defective fibrinolytic potential in cutaneous necrotizing venulitis

Autor: Maukizio Benci, Michael Dahm, Marco Matucci-Ceiunic, Patrizia Teofoli, Giuseppe Celasco, Ilaria Ghersetich, Torello Lotti, Claudio Comacchi, Dionigi Tsampau

Publikováno v: International journal of dermatology. 32(5)

Background. Cutaneous necrotizing venulitis (CNV) is a clinical disorder associated with segmental inflammation and fibrinoid necrosis of the dermal venules. It usually presents clinically as palpable purpura, even sometimes as nodules, bullae, ulcer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2fc60fb2055f26809a9adb41ec30961
https://pubmed.ncbi.nlm.nih.gov/8505166

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