A powerful machine learning approach to identify interactions of differentially abundant gut microbial subsets in patients with metastatic and non-metastatic pancreatic cancer

Autor: Annacandida Villani, Andrea Fontana, Concetta Panebianco, Carmelapia Ferro, Massimiliano Copetti, Radmila Pavlovic, Denise Drago, Carla Fiorentini, Fulvia Terracciano, Francesca Bazzocchi, Giuseppe Canistro, Federica Pisati, Evaristo Maiello, Tiziana Pia Latiano, Francesco Perri, Valerio Pazienza

Publikováno v: Gut Microbes, Vol 16, Iss 1 (2024)

Pancreatic cancer has a dismal prognosis, as it is often diagnosed at stage IV of the disease and is characterized by metastatic spread. Gut microbiota and its metabolites have been suggested to influence the metastatic spread by modulating the host

Externí odkaz: https://doaj.org/article/446dcba33e6342608bd3a9f711cc5699

BRAFV600E mutation impinges on gut microbial markers defining novel biomarkers for serrated colorectal cancer effective therapies

Autor: Valerio Pazienza, Francesca Bazzocchi, Tiziana Latiano, Angelo L. Vescovi, Concetta Panebianco, Giuseppe Canistro, Dario P. Cassano, Riccardo Pracella, Elena Binda, Alberto Visioli, Maria Grazia Cariglia, Chiara Barile, Fabrizio Giani, Nadia Trivieri, Amata Amy Soriano, Paola Parrella, Lucia Dimitri

Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-16 (2020)

Background Colorectal cancer (CRC) harboring BRAFV600E mutation exhibits low response to conventional therapy and poorest prognosis. Due to the emerging correlation between gut microbiota and CRC carcinogenesis, we investigated in serrated BRAFV600E

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2765f1d31894119ce2bccf358b95738a
https://doi.org/10.1186/s13046-020-01801-w

BRAFV600E mutation impinges on gut microbial markers defining novel biomarkers for serrated colorectal cancer effective therapies.

Autor: Trivieri, Nadia¹ (AUTHOR), Pracella, Riccardo¹ (AUTHOR), Cariglia, Maria Grazia¹ (AUTHOR), Panebianco, Concetta² (AUTHOR), Parrella, Paola³ (AUTHOR), Visioli, Alberto⁴ (AUTHOR), Giani, Fabrizio⁴ (AUTHOR), Soriano, Amata Amy¹ (AUTHOR), Barile, Chiara¹ (AUTHOR), Canistro, Giuseppe⁵ (AUTHOR), Latiano, Tiziana Pia⁶ (AUTHOR), Dimitri, Lucia⁷ (AUTHOR), Bazzocchi, Francesca⁵ (AUTHOR), Cassano, Dario⁵ (AUTHOR), Vescovi, Angelo L.^4,8 (AUTHOR), Pazienza, Valerio² (AUTHOR), Binda, Elena^1,9 (AUTHOR) e.binda@operapadrepio.it

Publikováno v: Journal of Experimental & Clinical Cancer Research (17569966). 12/14/2020, Vol. 39 Issue 1, p1-16. 16p.