Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Giuseppe Arancia"'
Autor:
Stefania Meschini, Maria Condello, Francesca Romana Gallo, Giuseppe Arancia, Giuseppina Multari
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 115:467-474
Previous investigations demonstrated that pretreatment with non-cytotoxic concentrations of voacamine had a chemosensitizing effect on cultured multidrug resistant osteosarcoma cells exposed to doxorubicin; whereas when used alone at high concentrati
Autor:
Gabriella Di Felice, Stefania Meschini, Giuseppina Multari, Maria Condello, Francesca Romana Gallo, Dario Cosentino, Silvia Corinti, Giuseppe Arancia
Publikováno v:
Journal of Natural Products
In previous studies it has been demonstrated that the plant alkaloid voacamine (1), used at noncytotoxic concentrations, enhanced the cytotoxicity of doxorubicin and exerted a chemosensitizing effect on cultured multidrug-resistant (MDR) U-2 OS-DX os
Publikováno v:
Microscopy Research and Technique. 76:1057-1069
Scanning (SEM) and transmission electron microscopy (TEM) are two fundamental microscopic techniques widely applied in biological research for the study of ultrastructural cell components. With these methods, especially TEM, it is possible to detect
Autor:
Paola Bendinelli, Leo J. Hofland, Francesco Cavagnini, Stefania Meschini, Monica Marra, Maria Condello, Sara Castiglioni, Silvia Zappavigna, Giovanni Vitale, Peter M. van Koetsveld, Alessandra Dicitore, Roberta Piccoletti, Michele Caraglia, Alfredo Budillon, Paola Maroni, Alberto Abbruzzese, Giuseppe Arancia
Publikováno v:
Biotechnology Advances, 30(1), 169-184. Elsevier Inc.
We have previously shown that cancer cells can protect themselves from apoptosis induced by type 1 interferons (IFNs) through a ras-->MAPK-mediated pathway. In addition, since IFN-mediated signalling components STATs are controlled by PPAR gamma we s
Autor:
Manuela Marra, Stefania Meschini, Pasquale Lista, Angelo De Milito, Giuseppe Arancia, Giuseppe Formisano, Maria Condello, Annarica Calcabrini, Elena Federici
Publikováno v:
Karolinska Institutet
In our previous studies, the bisindolic alkaloid voacamine (VOA), isolated from the plant Peschiera fuchsiaefolia, proved to exert a chemosensitizing effect on cultured multidrug resistant (MDR) osteosarcoma cells exposed to doxorubicin (DOX). In par
Autor:
Antonio Toninello, Elena Tibaldi, Anna Maria Brunati, Maria Lina Massimino, Marisa Colone, Enzo Agostinelli, Giuseppe Arancia, Annarita Stringaro
Publikováno v:
Journal of Cellular Biochemistry. 104:840-849
Mitochondrial tyrosine phosphorylation is emerging as an important mechanism in regulating mitochondrial function. This article, aimed at identifying which kinases are the major agents in mitochondrial tyrosine phosphorylation, shows that this role s
Autor:
Donatella Barisani, Anna Berardi, E. Ciraci, Antonina Parafioriti, Giuseppe Formisano, Gianfranco Bottazzo, Giuseppe Arancia
Publikováno v:
Experimental Hematology. 35:967-977
Objective. CD14(+) monocyte cell lines can differentiate into an osteoclast (OC)-like lineage. However, the identification of human cell lines with stem cell characteristics, capable of differentiating into OCs, would provide a tool for the study of
Publikováno v:
Biochemical Society Transactions. 35:343-348
Cytotoxic products of polyamines generated in situ by an enzyme-catalysed reaction may be useful as a new avenue in combating cancer. This study demonstrated that MDR (multidrug-resistant) cancer cells (colon adenocarcinoma and melanoma) are signific
Autor:
Alessandro Porrello, Enrico P. Spugnini, Giuseppe Formisano, Annarita Stringaro, Gennaro Citro, Agnese Molinari, Marisa Colone, Giuseppe Arancia
Publikováno v:
Microscopy Research and Technique. 70:1041-1050
Electroporation (EP) has been widely employed in the past years as a safe and effective technique to drive drugs and DNA plasmids into target cells both for experimental and therapeutic purposes. Despite the large bulk of literature on this topic, of
m-THPC-mediated photodynamic therapy of malignant gliomas: Assessment of a new transfection strategy
Autor:
Giulio Maira, Laura Toccacieli, Paola Luciani, Giovanna Mancini, Annunziato Mangiola, Marisa Colone, Cecilia Bombelli, Giuseppe Arancia, Annarica Calcabrini, Annarita Stringaro, Stefano Mannino, Agnese Molinari
Publikováno v:
International Journal of Cancer. 121:1149-1155
Malignant gliomas represent the most common primary brain tumor: more than 50% of them are glioblastoma multiforme (GBM). Photodynamic therapy may offer a very good chance of targeted destruction of infiltrating GBM cells, thus increasing the surviva