Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Giuseppe, Teti"'
Autor:
Cosme Claverie, Francesco Coppolino, Maria-Vittoria Mazzuoli, Cécile Guyonnet, Elise Jacquemet, Rachel Legendre, Odile Sismeiro, Giuseppe Valerio De Gaetano, Giuseppe Teti, Patrick Trieu-Cuot, Asmaa Tazi, Concetta Beninati, Arnaud Firon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Bacterial two-component systems (TCSs) are signaling modules that control physiology, adaptation, and host interactions. A typical TCS consists of a histidine kinase (HK) that activates a response regulator via phosphorylation in response to
Externí odkaz:
https://doaj.org/article/1069770797e1465dac3bf0517e390166
Autor:
Francesco Coppolino, Giuseppe Valerio De Gaetano, Cosme Claverie, Odile Sismeiro, Hugo Varet, Rachel Legendre, Angelica Pellegrini, Alessia Berbiglia, Luca Tavella, Germana Lentini, Agata Famà, Giulia Barbieri, Giampiero Pietrocola, Giuseppe Teti, Arnaud Firon, Concetta Beninati
Publikováno v:
mBio, Vol 15, Iss 9 (2024)
ABSTRACT Group B Streptococcus (GBS) is a pathobiont responsible for invasive infections in neonates and the elderly. The transition from a commensal to an invasive pathogen relies on the timely regulation of virulence factors. In this study, we char
Externí odkaz:
https://doaj.org/article/a051552e92534d0cad659bc8d5ff50a6
Autor:
Francesco Coppolino, Alessia Berbiglia, Germana Lentini, Agata Famà, Giampiero Pietrocola, Giuseppe Teti, Concetta Beninati, Giuseppe Valerio De Gaetano
Publikováno v:
Microorganisms, Vol 12, Iss 10, p 2096 (2024)
Streptococcus agalactiae, also known as Group B Streptococcus or GBS, is a commensal colonizer of human vaginal and gastrointestinal tracts that can also be a deadly pathogen for newborns, pregnant women, and the elderly. The SaeRS two-component regu
Externí odkaz:
https://doaj.org/article/9bcf7a3fc5c24d0a80f834453cc8f0c6
Autor:
Angelica Pellegrini, Germana Lentini, Agata Famà, Andrea Bonacorsi, Viola Camilla Scoffone, Silvia Buroni, Gabriele Trespidi, Umberto Postiglione, Davide Sassera, Federico Manai, Giampiero Pietrocola, Arnaud Firon, Carmelo Biondo, Giuseppe Teti, Concetta Beninati, Giulia Barbieri
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Group B Streptococcus (GBS) is a Gram-positive bacterium able to switch from a harmless commensal of healthy adults to a pathogen responsible for invasive infections in neonates. The signals and regulatory mechanisms governing this transition are sti
Externí odkaz:
https://doaj.org/article/2a565a165b3740278e49914fb859bab9
Autor:
Francesco Coppolino, Letizia Romeo, Giampiero Pietrocola, Germana Lentini, Giuseppe Valerio De Gaetano, Giuseppe Teti, Roberta Galbo, Concetta Beninati
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Binding to plasminogen (Plg) enables bacteria to associate with and invade host tissues. The cell wall protein PbsP significantly contributes to the ability of group B streptococci, a frequent cause of invasive infection, to bind Plg. Here we sought
Externí odkaz:
https://doaj.org/article/bcd8420c30ed40d4bee39b8854f8a875
Publikováno v:
Biomedical Journal, Vol 42, Iss 1, Pp 8-18 (2019)
One of the distinguishing features of the 1918 pandemic is the occurrence of massive, potentially detrimental, activation of the innate immune system in critically ill patients. Whether this reflects an intrinsic capacity of the virus to induce an ex
Externí odkaz:
https://doaj.org/article/ee748de96882481aab21f0280be6f83e
Autor:
Giuseppe Valerio De Gaetano, Germana Lentini, Roberta Galbo, Francesco Coppolino, Agata Famà, Giuseppe Teti, Concetta Beninati
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0253242 (2021)
Streptococcus agalactiae (group B streptococcus or GBS) is a commensal bacterium that can frequently behave as a pathogen, particularly in the neonatal period and in the elderly. The gut is a primary site of GBS colonization and a potential port of e
Externí odkaz:
https://doaj.org/article/0c15dfc17b604a7f9a31228ae814f945
Autor:
Agata Famà, Angelina Midiri, Giuseppe Mancuso, Carmelo Biondo, Germana Lentini, Roberta Galbo, Maria Miriam Giardina, Giuseppe Valerio De Gaetano, Letizia Romeo, Giuseppe Teti, Concetta Beninati
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Streptococcus pneumoniae (or pneumococcus) is a highly prevalent human pathogen. Toll-like receptors (TLRs) function as immune sensors that can trigger host defenses against this bacterium. Defects in TLR-activated signaling pathways, includ
Externí odkaz:
https://doaj.org/article/e74b5fe5626a402aa73773157b57416c
Autor:
Astrid Skjesol, Mariia Yurchenko, Korbinian Bösl, Caroline Gravastrand, Kaja Elisabeth Nilsen, Lene Melsæther Grøvdal, Federica Agliano, Francesco Patane, Germana Lentini, Hera Kim, Giuseppe Teti, Aditya Kumar Sharma, Richard K Kandasamy, Bjørnar Sporsheim, Kristian K Starheim, Douglas T Golenbock, Harald Stenmark, Mary McCaffrey, Terje Espevik, Harald Husebye
Publikováno v:
PLoS Pathogens, Vol 15, Iss 3, p e1007684 (2019)
Phagocytosis is a complex process that eliminates microbes and is performed by specialised cells such as macrophages. Toll-like receptor 4 (TLR4) is expressed on the surface of macrophages and recognizes Gram-negative bacteria. Moreover, TLR4 has bee
Externí odkaz:
https://doaj.org/article/0154430610c447ce88ec48ab14ae47bf
Autor:
Giuseppe Valerio De Gaetano, Mario Venza, Germana Lentini, Francesco Coppolino, Agata Famà, Roberta Galbo, Giuseppe Teti, Concetta Beninati
Publikováno v:
The Journal of Immunology. 207:1448-1455
Identification of the receptors involved in innate immune recognition of Staphylococcus aureus, a major cause of morbidity and mortality in humans, is essential to develop alternative strategies to treat infections caused by antibiotic-resistant stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57b0db6c79ceb6801f54fe99299ed8db
https://doi.org/10.4049/jimmunol.2100389
https://doi.org/10.4049/jimmunol.2100389