Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Giuseppe, Militello"'
Familial hypercholesterolemia class II low-density lipoprotein receptor response to statin treatment
Autor:
Linda Omer, Lubna Hindi, Giuseppe Militello, Katlin B. Stivers, Kenneth C. Tien, Nolan L. Boyd
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 4 (2020)
Low-density lipoprotein (LDL) receptor (LDLR) mutations are the primary cause of familial hypercholesterolemia (FH). Class II LDLR mutations result in a misfolded LDLR retained in the endoplasmic reticulum (ER). We have developed a model of FH class
Externí odkaz:
https://doaj.org/article/f9dcfe7f309a40e08c03b4e56633c732
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
In recent years, the role of RNA has expanded to the extent that protein-coding RNAs are now the minority with a variety of non-coding RNAs (ncRNAs) now comprising the majority of RNAs in higher organisms. A major contributor to this shift in underst
Externí odkaz:
https://doaj.org/article/8a5c1d11e7aa4207b06d814072881cdd
The A-to-I RNA Editing Enzyme Adar1 Is Essential for Normal Embryonic Cardiac Growth and Development
Autor:
Anna M. Gumpert, Annalara G. Fischer, Marcin Wysoczynski, Giuseppe Militello, Ghazal Sadri, Joseph B. Moore, Shizuka Uchida, Thomas Braun, Tyler Weirick
Publikováno v:
Circ Res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a42f2f7da3790e43232c1ad7c2772ae3
https://europepmc.org/articles/PMC7415551/
https://europepmc.org/articles/PMC7415551/
Autor:
Claudia Döring, Shizuka Uchida, Hosen Mr, Giuseppe Militello, Ashok Kumar, Tyler Weirick, Zhang L, So-ichiro Fukada, Stefanie Dimmeler, David John, Kamel Mamchaoui, Yuliya Ponomareva, Sajedah M. Hindi, Pascal Gellert, Nakamura M, Mouly
Publikováno v:
J Mol Cell Biol
Myogenesis is a complex process required for skeletal muscle formation during embryonic development and for regeneration and growth of myofibers in adults. Accumulating evidence suggests that long non-coding RNAs (lncRNAs) play key roles in regulatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c0710c03e0a71bd69301cb29b0048f2
https://doi.org/10.1093/jmcb/mjy025
https://doi.org/10.1093/jmcb/mjy025
Autor:
Giuseppe Militello, Shizuka Uchida, Mohammed Rabiul Hosen, David John, Tyler Weirick, Joseph B. Moore
Publikováno v:
High-Throughput
Volume 8
Issue 4
Volume 8
Issue 4
Studies in epitranscriptomics indicate that RNA is modified by a variety of enzymes. Among these RNA modifications, adenosine to inosine (A-to-I) RNA editing occurs frequently in the mammalian transcriptome. These RNA editing sites can be detected di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f84a8c70a9bb503e0b3245adfcc7abf
https://pubmed.ncbi.nlm.nih.gov/31795425
https://pubmed.ncbi.nlm.nih.gov/31795425
Familial hypercholesterolemia class II low-density lipoprotein receptor response to statin treatment
Autor:
Giuseppe Militello, Nolan L. Boyd, Linda Omer, Kenneth C. Tien, Lubna Hindi, Katlin B. Stivers
Publikováno v:
Disease Models & Mechanisms
article-version (VoR) Version of Record
Disease Models & Mechanisms, Vol 13, Iss 4 (2020)
article-version (VoR) Version of Record
Disease Models & Mechanisms, Vol 13, Iss 4 (2020)
Low-density lipoprotein (LDL) receptor (LDLR) mutations are the primary cause of familial hypercholesterolemia (FH). Class II LDLR mutations result in a misfolded LDLR retained in the endoplasmic reticulum (ER). We have developed a model of FH class
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00cdb48e3a7983ee32865f7c278f8279
https://pubmed.ncbi.nlm.nih.gov/32005714
https://pubmed.ncbi.nlm.nih.gov/32005714
Autor:
Mitali G. Chitre, Bethany W. Long, Linda T. Harrison, Lauren A. Higgins, Giuseppe Militello, Shizuka Uchida, Daniel W. Riggs, Anna M. Gumpert, Kenneth R. Brittian, Steven P. Jones, Timothy N. Audam, Andrea Jurkovic, Senthilkumar K. Muthusamy, Sujith Dassanayaka
Publikováno v:
Basic Res Cardiol
Several post-translational modifications figure prominently in ventricular remodeling. The beta-O-linkage of N-acetylglucosamine (O-GlcNAc) to proteins has emerged as an important signal in the cardiovascular system. Although there are limited insigh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b6917eb8ececbdd99bd872147fc973
https://doi.org/10.1007/s00395-019-0737-y
https://doi.org/10.1007/s00395-019-0737-y
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Frontiers in Physiology
Frontiers in Physiology
In recent years, the role of RNA has expanded to the extent that protein-coding RNAs are now the minority with a variety of non-coding RNAs (ncRNAs) now comprising the majority of RNAs in higher organisms. A major contributor to this shift in underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ec7721ae7981431a4785c713e8f215
https://doi.org/10.3389/fphys.2018.00522
https://doi.org/10.3389/fphys.2018.00522
Autor:
Giuseppe Militello, David John, Tyler Weirick, Stefanie Dimmeler, Raphael Müller, Shizuka Uchida
Publikováno v:
Briefings in Bioinformatics. 17:678-685
Owing greatly to the advancement of next-generation sequencing (NGS), the amount of NGS data is increasing rapidly. Although there are many NGS applications, one of the most commonly used techniques 'RNA sequencing (RNA-seq)' is rapidly replacing mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20890f3ad28d4f6af3328c36ede51650
https://doi.org/10.1093/bib/bbv067
https://doi.org/10.1093/bib/bbv067
Autor:
Raphael Müller, Giuseppe Militello, Wei Chen, Tyler Weirick, Shizuka Uchida, Stefanie Dimmeler, David John
Publikováno v:
Scientific Reports
Increasing evidence indicates the presence of long noncoding RNAs (lncRNAs) is specific to various cell types. Although lncRNAs are speculated to be more numerous than protein-coding genes, the annotations of lncRNAs remain primitive due to the lack
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b8189939080c9fa06167fbd7c3d7513
https://pubmed.ncbi.nlm.nih.gov/27582018
https://pubmed.ncbi.nlm.nih.gov/27582018