Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Giulio Nannetti"'
Autor:
Gilda Giancotti, Giulio Nannetti, Gilda Padalino, Martina Landini, Nanci Santos-Ferreira, Jana Van Dycke, Valentina Naccarato, Usheer Patel, Romano Silvestri, Johan Neyts, Roberto Gozalbo-Rovira, Jésus Rodríguez-Díaz, Joana Rocha-Pereira, Andrea Brancale, Salvatore Ferla, Marcella Bassetto
Publikováno v:
Viruses, Vol 15, Iss 1, p 74 (2022)
Human norovirus is the first cause of foodborne disease worldwide, leading to extensive outbreaks of acute gastroenteritis, and causing around 200,000 children to die annually in developing countries. No specific vaccines or antiviral agents are curr
Externí odkaz:
https://doaj.org/article/27e3ed865621461a88dd40d0d9b0283f
Targeting the Complement Serine Protease MASP-2 as a Therapeutic Strategy for Coronavirus Infections
Autor:
Ben M. Flude, Giulio Nannetti, Paige Mitchell, Nina Compton, Chloe Richards, Meike Heurich, Andrea Brancale, Salvatore Ferla, Marcella Bassetto
Publikováno v:
Viruses, Vol 13, Iss 2, p 312 (2021)
MASP-2, mannose-binding protein-associated serine protease 2, is a key enzyme in the lectin pathway of complement activation. Hyperactivation of this protein by human coronaviruses SARS-CoV, MERS-CoV and SARS-CoV-2 has been found to contribute to abe
Externí odkaz:
https://doaj.org/article/4a32bb5074b44cce89badf40879d8d17
Autor:
Saverio G. Parisi, Arianna Loregian, Samantha Andreis, Giulio Nannetti, Silvia Cavinato, Monica Basso, Renzo Scaggiante, Federico Dal Bello, Lorenzo Messa, Anna Maria Cattelan, Giorgio Palù
Publikováno v:
International Journal of Infectious Diseases, Vol 49, Iss C, Pp 151-153 (2016)
Objectives: Effective treatment with direct-acting antiviral drugs against hepatitis C virus (HCV) is a medical need in cirrhotic HIV–HCV co-infected patients. Methods: This study investigated the plasma levels of daclatasvir (DCV) and ribavirin (R
Externí odkaz:
https://doaj.org/article/ea33f99ee10f488ea077ed968f904102
Autor:
Gilda Giancotti, Giulio Nannetti, Gilda Padalino, Martina Landini, Nanci Santos-Ferreira, Jana Van Dycke, Valentina Naccarato, Usheer Patel, Romano Silvestri, Johan Neyts, Roberto Gozalbo-Rovira, Jésus Rodríguez-Díaz, Joana Rocha-Pereira, Andrea Brancale, Salvatore Ferla, Marcella Bassetto
Publikováno v:
Viruses; Volume 15; Issue 1; Pages: 74
Giancotti, Gilda Gozalbo Rovira, Roberto Vicente Rodríguez Díaz, Jesús 2022 Structural investigations on novel non-nucleoside inhibitors of human norovirus polymerase Viruses 15 74
Giancotti, Gilda Gozalbo Rovira, Roberto Vicente Rodríguez Díaz, Jesús 2022 Structural investigations on novel non-nucleoside inhibitors of human norovirus polymerase Viruses 15 74
Human norovirus is the first cause of foodborne disease worldwide, leading to extensive outbreaks of acute gastroenteritis, and causing around 200,000 children to die annually in developing countries. No specific vaccines or antiviral agents are curr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69c78338d0c9db777fa91c48ffb84d0
https://lirias.kuleuven.be/handle/20.500.12942/712754
https://lirias.kuleuven.be/handle/20.500.12942/712754
Targeting the Complement Serine Protease MASP-2 as a Therapeutic Strategy for Coronavirus Infections
Autor:
Andrea Brancale, Ben Matthew Flude, Giulio Nannetti, Meike Heurich, Salvatore Ferla, Nina Compton, Chloe Richards, Marcella Bassetto, Paige Mitchell
Publikováno v:
Viruses
Volume 13
Issue 2
Viruses, Vol 13, Iss 312, p 312 (2021)
Volume 13
Issue 2
Viruses, Vol 13, Iss 312, p 312 (2021)
MASP-2, mannose-binding protein-associated serine protease 2, is a key enzyme in the lectin pathway of complement activation. Hyperactivation of this protein by human coronaviruses SARS-CoV, MERS-CoV and SARS-CoV-2 has been found to contribute to abe
Autor:
Leonardo Tensi, Laura Goracci, Giulio Nannetti, Chiara Bertagnin, Serena Massari, Stefano Di Bona, Maria Chiara Pismataro, Giuseppe Manfroni, Tommaso Felicetti, María Isabel Loza, Arianna Loregian, Anna Donnadio, José Brea, Stefano Sabatini, Violetta Cecchetti, Oriana Tabarrini, Maria Giulia Nizi
Publikováno v:
European Journal of Medicinal Chemistry
Influenza viruses (Flu) are responsible for seasonal epidemics causing high rates of morbidity, which can dramatically increase during severe pandemic outbreaks. Antiviral drugs are an indispensable weapon to treat infected people and reduce the impa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3696c65725a31b0c9e95dec6ef66d3b
http://hdl.handle.net/11577/3379486
http://hdl.handle.net/11577/3379486
Autor:
Jenny Desantis, Arianna Loregian, Giuseppe Manfroni, Oriana Tabarrini, Laura Goracci, Giulio Nannetti, Violetta Cecchetti, Serena Massari, Giorgio Palù, Maria Letizia Barreca
Publikováno v:
European Journal of Medicinal Chemistry. 138:128-139
With the aim to identify small molecules able to disrupt PA-PB1 subunits interaction of influenza virus (flu) RNA-dependent RNA polymerase, and based on previous structural and computational information, in this paper we have designed and synthesized
Isavuconazole is a broad‐spectrum triazole antifungal drug recently approved for the therapy of both invasive aspergillosis and mucormycosis. To support a widespread therapeutic drug monitoring of isavuconazole, a simple, sensitive, and precise hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c323c72372af9754903a46d4651cf570
Autor:
Arianna Loregian, Beatrice Mercorelli, Serena Massari, Giorgio Palù, Giulio Nannetti, Jenny Desantis, Chiara Bertagnin, Oriana Tabarrini
Publikováno v:
Antiviral Research
Influenza viruses are major respiratory pathogens responsible for both seasonal epidemics and occasional pandemics worldwide. The current available treatment options have limited efficacy and thus the development of new antivirals is highly needed. W
Autor:
Iuni M. L. Trist, Arianna Loregian, Giancarlo Grossi, Francesca Musumeci, Maurizio Botta, Giorgio Palù, Davide Deodato, Giulio Nannetti, Ilaria D'Agostino, Anna Lucia Fallacara, Ylenia Cau, Silvia Schenone, Ilaria Giacchello
The limited treatment options against influenza virus along with the growing public health concerns regarding the continuous emergence of drug-resistant viruses make essential the development of new anti-flu agents with novel mechanisms of action. On
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674976e7738a4bf445d99c2fdd826571
http://hdl.handle.net/11365/1063334
http://hdl.handle.net/11365/1063334