Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Giulio Francia"'
Autor:
Xiaoyang Liu, Sandhya Chipurupalli, Peijia Jiang, Mahtab Tavasoli, Byong Hoon Yoo, Michael McPhee, Sina Mazinani, Giulio Francia, Robert S. Kerbel, Kirill V. Rosen
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-10 (2022)
Abstract A significant proportion of breast cancers are driven by ErbB2/Her2 oncoprotein that they overexpress. These malignancies are typically treated with various ErbB2-targeted drugs, but many such cancers develop resistance to these agents and b
Externí odkaz:
https://doaj.org/article/62c51b2c6a6e49339069aafeeb337811
Autor:
Cuipeng Qiu, Xiao Wang, Serina A. Batson, Bofei Wang, Carlos A. Casiano, Giulio Francia, Jian-Ying Zhang
Publikováno v:
Cancers, Vol 15, Iss 16, p 4064 (2023)
(1) Background: Autoantibodies to tumor-associated antigens (TAAs) have emerged as promising cancer biomarkers. Luminex technology offers a powerful approach for the simultaneous detection of multiple anti-TAA autoantibodies. (2) Methods: We aimed to
Externí odkaz:
https://doaj.org/article/741f75b12bb34e21810821efcae67644
Cyclic Metronomic Chemotherapy for Pediatric Tumors: Six Case Reports and a Review of the Literature
Autor:
Benjamin Carcamo, Giulio Francia
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 10, p 2849 (2022)
We report a retrospective case series of six Hispanic children with tumors treated with metronomic chemotherapy. The six cases comprised one rhabdoid tumor of the kidney, one ependymoma, two medulloblastomas, one neuroblastoma, and a type II neurocyt
Externí odkaz:
https://doaj.org/article/64d2dedf2b97451e8c4f08343b199023
Autor:
Li Xu, Ryan Gordon, Rebecca Farmer, Abhinandan Pattanayak, Andrew Binkowski, Xiaoke Huang, Michael Avram, Sankar Krishna, Eric Voll, Janet Pavese, Juan Chavez, James Bruce, Andrew Mazar, Antoinette Nibbs, Wayne Anderson, Lin Li, Borko Jovanovic, Sean Pruell, Matias Valsecchi, Giulio Francia, Rick Betori, Karl Scheidt, Raymond Bergan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
In this study, the authors identify and validate a halogen-substituted isoflavanone able to inhibit prostate cancer cell motility, invasion and metastasis in vitro and in vivo. They demonstrate its ability to selectively inhibit activation of client
Externí odkaz:
https://doaj.org/article/bfb4cee65d69447bbe13390df2a07b87
Autor:
Valeria Rolih, Jerri Caldeira, Elisabetta Bolli, Ahmad Salameh, Laura Conti, Giuseppina Barutello, Federica Riccardo, Jolanda Magri, Alessia Lamolinara, Karla Parra, Paloma Valenzuela, Giulio Francia, Manuela Iezzi, Federica Pericle, Federica Cavallo
Publikováno v:
Cancers, Vol 12, Iss 6, p 1492 (2020)
Metastatic breast cancer (MBC) is the leading cause of cancer death in women due to recurrence and resistance to conventional therapies. Thus, MBC represents an important unmet clinical need for new treatments. In this paper we generated a virus-like
Externí odkaz:
https://doaj.org/article/cc38e70cf047417a9c077ed1a7b8614c
Autor:
Inga B Fricke, Raquel De Souza, Lais Costa Ayub, Giulio Francia, Robert Kerbel, David A Jaffray, Jinzi Zheng
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196892 (2018)
Preclinical breast cancer models recapitulating the clinical course of metastatic disease are crucial for drug development. Highly metastatic cell lines forming spontaneous metastasis following orthotopic implantation were previously developed and ch
Externí odkaz:
https://doaj.org/article/890f83c3666a49c6a3928d72dc7dcc3d
Autor:
Guido Bocci, Anna Fioravanti, Paola Orlandi, Teresa Di Desidero, Gianfranco Natale, Giovanni Fanelli, Paolo Viacava, Antonio Giuseppe^Naccarato, Giulio Francia, Romano Danesi
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 9, Pp 833-845 (2012)
AIMS: To evaluate the antitumor and antiangiogenic activity of metronomic ceramide analogs and their relevant molecular mechanisms. METHODS: Human endothelial cells [human dermal microvascular endothelial cells and human umbilical vascular endothelia
Externí odkaz:
https://doaj.org/article/424e515d3d2340ba94e2741890af427b
Autor:
Urban Emmenegger, Giulio Francia, Annabelle Chow, Yuval Shaked, Andrew Kouri, Shan Man, Robert S. Kerbel
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 1, Pp 40-48 (2011)
Low-dose metronomic (LDM) chemotherapy is emerging as an alternative or supplemental dosing strategy to conventional maximum tolerated dose (MTD) chemotherapy. It is characterized primarily, but not exclusively, by antiangiogenic mechanisms of action
Externí odkaz:
https://doaj.org/article/69848885684c4672bf9a79025fe2a446
Autor:
Terence C. Tang, Shan Man, Ping Xu, Giulio Francia, Kae Hashimoto, Urban Emmenegger, Robert S. Kerbel
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 11, Pp 928-940 (2010)
Acquired resistance to antiangiogenic drugs, such as sorafenib, is a major clinical problem. We studied development of a resistance to sorafenib in new preclinical models of human hepatocellular carcinoma (HCC) along with a strategy to delay such res
Externí odkaz:
https://doaj.org/article/7d4360fe233b43e3a0454b3cd2ae3f7a
Autor:
Robert S. Kerbel, F. Stuart Foster, Anne H. Dantzig, Mark Uhlik, Julie Stewart, Christina Hackl, Shan Man, Ping Xu, Carolyn Cesta, Melissa Yin, John Sun, Kae Hashimoto, Yuval Shaked, Giulio Francia
AVI file - 4.9MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d06741e77b0dcdc2670337f5bc6a218
https://doi.org/10.1158/1535-7163.22497931
https://doi.org/10.1158/1535-7163.22497931