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1498 Deploying spatial transcriptomics to inform on intratumoral heterogeneity in late-stage uveal melanoma leveraging advanced preclinical modeling and clinical samples

Autor: Scott Woodman, Joseph Marszalek, Alexander J Lazar, Christopher Terranova, Meng He, Timothy Heffernan, Khalida Wani, Jason Gay, Phillip Andrew Futreal, Sanjana Srinivasan, Johnathon Rose, Joseph R Daniele, Michael Peoples, Rosalba Minelli, Chiu-Yi Liu, Melinda Soeung, Luigi Perelli, Dmitry Loza, Ningping Feng, Christopher P Vellano, Giulio F Draetta, Alessandro Carugo, Giannicola Genovese, Virginia Giuliani

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

Externí odkaz: https://doaj.org/article/573b4407054247a7b16dcebb66935ad8

Lineage-coupled clonal capture identifies clonal evolution mechanisms and vulnerabilities of BRAFV600E inhibition resistance in melanoma

Autor: Ze-Yan Zhang, Yingwen Ding, Ravesanker Ezhilarasan, Tenzin Lhakhang, Qianghu Wang, Jie Yang, Aram S. Modrek, Hua Zhang, Aristotelis Tsirigos, Andrew Futreal, Giulio F. Draetta, Roel G. W. Verhaak, Erik P. Sulman

Publikováno v: Cell Discovery, Vol 8, Iss 1, Pp 1-23 (2022)

Abstract Targeted cancer therapies have revolutionized treatment but their efficacies are limited by the development of resistance driven by clonal evolution within tumors. We developed “CAPTURE”, a single-cell barcoding approach to comprehensive

Externí odkaz: https://doaj.org/article/e91108592f504fbf93459cedf14bc51e

The KELT Follow-Up Network and Transit False Positive Catalog: Pre-vetted False Positives for TESS

Autor: Collins, Karen A., Collins, Kevin I., Pepper, Joshua, Labadie-Bartz, Jonathan, Stassun, Keivan, Gaudi, B. Scott, Bayliss, Daniel, Bento, Joao, Colón, Knicole D., Feliz, Dax, James, David, Johnson, Marshall C., Kuhn, Rudolf B., Lund, Michael B., Penny, Matthew T., Rodriguez, Joseph E., Siverd, Robert J., Stevens, Daniel J., Yao, Xinyu, Zhou, George, Akshay, Mundra, Aldi, Giulio F., Ashcraft, Cliff, Awiphan, Supachai, Baştürk, Özgür, Baker, David, Beatty, Thomas G., Benni, Paul, Berlind, Perry, Berriman, G. Bruce, Berta-Thompson, Zach, Bieryla, Allyson, Bozza, Valerio, Novati, Sebastiano Calchi, Calkins, Michael L., Cann, Jenna M., Ciardi, David R., Clark, Ian R., Cochran, William D., Cohen, David H., Conti, Dennis, Crepp, Justin R., Curtis, Ivan A., D'Ago, Giuseppe, Diazeguigure, Kenny A., Dressing, Courtney D., Dubois, Franky, Ellingson, Erica, Ellis, Tyler G., Esquerdo, Gilbert A., Evans, Phil, Friedli, Alison, Fukui, Akihiko, Fulton, Benjamin J., Gonzales, Erica J., Good, John C., Gregorio, Joao, Gumusayak, Tolga, Hancock, Daniel A., Harada, Caleb K., Hart, Rhodes, Hintz, Eric G., Jang-Condell, Hannah, Jeffery, Elizabeth J., Jensen, Eric L. N., Jofré, Emiliano, Joner, Michael D., Kar, Aman, Kasper, David H., Keten, Burak, Kielkopf, John F., Komonjinda, Siramas, Kotnik, Cliff, Latham, David W., Leuquire, Jacob, Lewis, Tiffany R., Logie, Ludwig, Lowther, Simon J., MacQueen, Phillip J., Martin, Trevor J., Mawet, Dimitri, McLeod, Kim K., Murawski, Gabriel, Narita, Norio, Nordhausen, Jim, Oberst, Thomas E., Odden, Caroline, Panka, Peter A., Petrucci, Romina, Plavchan, Peter, Quinn, Samuel N., Rau, Steve, Reed, Phillip A., Relles, Howard, Renaud, Joe P., Scarpetta, Gaetano, Sorber, Rebecca L., Spencer, Alex D., Spencer, Michelle, Stephens, Denise C., Stockdale, Chris, Tan, Thiam-Guan, Trueblood, Mark, Trueblood, Patricia, Vanaverbeke, Siegfried, Villanueva Jr., Steven, Warner, Elizabeth M., West, Mary Lou, Yalçınkaya, Selçuk, Yeigh, Rex, Zambelli, Roberto

The Kilodegree Extremely Little Telescope (KELT) project has been conducting a photometric survey for transiting planets orbiting bright stars for over ten years. The KELT images have a pixel scale of ~23"/pixel---very similar to that of NASA's Trans

Externí odkaz: http://arxiv.org/abs/1803.01869

Platelet and immune signature associated with a rapid response to the BNT162b2 mRNA COVID‐19 vaccine

Autor: Flego, Davide, Cesaroni, Simone, Romiti, Giulio F., Corica, Bernadette, Marrapodi, Ramona, Scafa, Noemi, Maiorca, Francesca, Lombardi, Ludovica, Pallucci, Davide, Pulcinelli, Fabio, Raparelli, Valeria, Visentini, Marcella, Cangemi, Roberto, Piconese, Silvia, Alvaro, Domenico, Polimeni, Antonella, Basili, Stefania, Stefanini, Lucia ^*

Publikováno v: In Journal of Thrombosis and Haemostasis April 2022 20(4):961-974