Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Giulio Bertaccini"'
Publikováno v:
Alimentary Pharmacology & Therapeutics. 5:585-591
SUMMARY This review examines the evidence for the existence in the gastrointestinal tract of a new subtype (H3) of histamine receptors, previously described in the central nervous system. Study of these receptors is facilitated by the availability of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b6fcb698bcd83e5078bcb8d19c188a0
https://doi.org/10.1111/j.1365-2036.1991.tb00526.x
https://doi.org/10.1111/j.1365-2036.1991.tb00526.x
Publikováno v:
Alimentary Pharmacology & Therapeutics. 9:615-623
SUMMARY Background: The mechanisms responsible for the gastric ulcerogenic effect of indomethacin are unclear. The importance of basal acid secretion on morphological changes by indomethacin was investigated. Methods: Gastric lesions were macroscopic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37573bfbf5b98a3209efc4750bb1349d
https://doi.org/10.1111/j.1365-2036.1995.tb00430.x
https://doi.org/10.1111/j.1365-2036.1995.tb00430.x
Publikováno v:
Journal of Physiology-Paris. 94:1-4
The effect of the selective histamine H3 receptor agonists (R)alpha-methylhistamine, (R)MHA and immepip (IMM) on intestinal smooth muscle contractility was investigated on isolated cells from the longitudinal muscle of the guinea pig ileum. (R)MHA (1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa86b27abe97df06e506c56e8f60894
https://doi.org/10.1016/s0928-4257(99)00110-2
https://doi.org/10.1016/s0928-4257(99)00110-2
Publikováno v:
Pharmacology. 59:192-200
The histamine H3 receptor shows high degree of stereoselectivity for histamine analogues branched in the side chain. The hypothesis that gastroprotection by (R)-α-methylhistamine could be H3 receptor-mediated was tested by comparing the effect of (R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::209d562e20f18b565df36a6084ea8102
https://doi.org/10.1159/000028320
https://doi.org/10.1159/000028320
Publikováno v:
General Pharmacology: The Vascular System. 31:643-651
1. The histamine H 2 receptor agonists, dimaprit, impromidine, amthamine, and several dimaprit- and impromidine-analogues were investigated for their spasmolytic activity on the guinea pig duodenum, precontracted with acetylcholine or KCl. 2. Almost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e3aa9c67dfa3df86f90ffe1b33683bb
https://doi.org/10.1016/s0306-3623(98)00077-9
https://doi.org/10.1016/s0306-3623(98)00077-9
Publikováno v:
Pharmacology. 56:281-284
The compound fedotozine, recently described as a peripheral kappa opioid receptor agonist, was tested on smooth muscle cells isolated from the longitudinal muscle layer of the guinea pig ileum, in comparison with the selective kappa receptor agonist,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ffdda33b3288a316ac4beaad20bd80c
https://doi.org/10.1159/000028210
https://doi.org/10.1159/000028210
Publikováno v:
Life Sciences. 62:PL13-PL18
The influence of pretreatment with (R)-alpha-methylhistamine, selective agonist of histamine H3 receptors, has been investigated on gastric mucosal lesions at different time intervals, from 5 to 60 minutes, after administration of absolute ethanol in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ec7b81163ea196d48f14f1b849ee20
https://doi.org/10.1016/s0024-3205(97)01043-6
https://doi.org/10.1016/s0024-3205(97)01043-6
Publikováno v:
Journal of Physiology-Paris. 91:199-202
The effects of histamine and dimaprit on intestinal smooth muscle contractility were investigated on isolated cells from longitudinal muscle of the guinea pig ileum. Both histamine (10(-14)-10(-10) M) and dimaprit (10(-13)-10(-10) M) exerted a concen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29629104a3fc43657aa180c49f5bf99b
https://doi.org/10.1016/s0928-4257(97)89484-3
https://doi.org/10.1016/s0928-4257(97)89484-3
Publikováno v:
Digestive Diseases and Sciences. 42:1020-1028
(R)-α-Methylhistamine, a selective agonistof histamine H3 receptors, preventsmacroscopically visible gastric lesions by absoluteethanol in the rat. A further insight into its activitywas the aim of our study. Rats were given saline or(R)-α-methylhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f45bc78581a4c1c60a4ed40274867e9
https://doi.org/10.1023/a:1018841204104
https://doi.org/10.1023/a:1018841204104
Autor:
Gabriella Coruzzi, Giulio Bertaccini
Publikováno v:
Digestive Diseases and Sciences. 40:2052-2063
The distribution and functions of histamine H3 receptors in the gastrointestinal tract is reviewed with particular reference to the effects on gastric acid secretion, mucosal protection, and intestinal motility. Histamine H3 receptor activation has n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1360e2b93c6f09dc00d7c2d3e29233f6
https://doi.org/10.1007/bf02208678
https://doi.org/10.1007/bf02208678