Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Giulio Alberini"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 2640-2653 (2023)
Tight-junctions (TJs) are multi-protein complexes between adjacent endothelial or epithelial cells. In the blood-brain-barrier (BBB), they seal the paracellular space and the Claudin-5 (Cldn5) protein forms their backbone. Despite the fundamental rol
Externí odkaz:
https://doaj.org/article/144dd1b5f6b14e5ba7375c8cdc5cd5b9
Autor:
Bruno Sterlini, Francesca Franchi, Lisastella Morinelli, Beatrice Corradi, Chiara Parodi, Martina Albini, Alessandra Bianchi, Antonella Marte, Pietro Baldelli, Giulio Alberini, Luca Maragliano, Pierluigi Valente, Fabio Benfenati, Anna Corradi
Publikováno v:
Neurobiology of Disease, Vol 183, Iss , Pp 106177- (2023)
PRRT2 is a neuronal protein that controls neuronal excitability and network stability by modulating voltage-gated Na+ channel (Nav). PRRT2 pathogenic variants cause pleiotropic syndromes including epilepsy, paroxysmal kinesigenic dyskinesia and episo
Externí odkaz:
https://doaj.org/article/213d01efb0dc4b71bc3a8d98e098919a
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 5984-6010 (2022)
Claudins (Cldns) define a family of transmembrane proteins that are the major determinants of the tight junction integrity and tissue selectivity. They promote the formation of either barriers or ion-selective channels at the interface between two fa
Externí odkaz:
https://doaj.org/article/e9e3befffbc44022b845e9bb75b35783
Autor:
Mattia Bramini, Giulio Alberini, Elisabetta Colombo, Martina Chiacchiaretta, Mattia L. DiFrancesco, José F. Maya-Vetencourt, Luca Maragliano, Fabio Benfenati, Fabrizia Cesca
Publikováno v:
Frontiers in Systems Neuroscience, Vol 12 (2018)
The scientific community has witnessed an exponential increase in the applications of graphene and graphene-based materials in a wide range of fields, from engineering to electronics to biotechnologies and biomedical applications. For what concerns n
Externí odkaz:
https://doaj.org/article/97069b750ad64f9c88939f118c3890c0
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0193383 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0184190.].
Externí odkaz:
https://doaj.org/article/03fdd8255f9f47fab7427078d0d0d8dc
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184190 (2017)
Tight-junctions between epithelial cells of biological barriers are specialized molecular structures that regulate the flux of solutes across the barrier, parallel to cell walls. The tight-junction backbone is made of strands of transmembrane protein
Externí odkaz:
https://doaj.org/article/82e0109cec1844bb8156ec1e6ccaaaaf
Autor:
Giulio Alberini, Sergio Alexis Paz, Beatrice Corradi, Cameron F. Abrams, Fabio Benfenati, Luca Maragliano
Publikováno v:
Journal of Chemical Theory and Computation. 19:2953-2972
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65d86c779c1e28396c1e78994fdf7af7
https://doi.org/10.1021/acs.jctc.2c00990
https://doi.org/10.1021/acs.jctc.2c00990
Publikováno v:
ACS Chemical Neuroscience. 13:2140-2153
The blood-brain barrier (BBB) strictly regulates the exchange of ions and molecules between the blood and the central nervous system. Tight junctions (TJs) are multimeric structures that control the transport through the paracellular spaces between t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::104143243dd69b0e8d02edf61682371c
https://doi.org/10.1021/acschemneuro.2c00139
https://doi.org/10.1021/acschemneuro.2c00139
Autor:
Giulio Alberini, S. Alexis Paz, Beatrice Corradi, Cameron Abrams, Fabio Benfenati, Luca Maragliano
The recent determination of cryo-EM structures of voltage-gated sodium (Nav)channels has revealed many details of these proteins. However, knowledge of ionic permeation through the Nav pore remains limited. In this work, we performed atomistic molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d64c9527b1ca2673a178aad9d3efc22
https://doi.org/10.1101/2022.09.29.509656
https://doi.org/10.1101/2022.09.29.509656
Autor:
Francesca Franchi, Antonella Marte, Beatrice Corradi, Bruno Sterlini, Giulio Alberini, Alessandra Romei, Antonio De Fusco, Alexander Vogel, Luca Maragliano, Pietro Baldelli, Anna Corradi, Pierluigi Valente, Fabio Benfenati
Publikováno v:
Journal of Biological Chemistry. 299:104632
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a1ab02da97e801b0be3b2caf3ee6d2d
https://doi.org/10.1016/j.jbc.2023.104632
https://doi.org/10.1016/j.jbc.2023.104632