Zobrazeno 1 - 10
of 375
pro vyhledávání: '"Giulio, Draetta"'
Autor:
Virginia Giuliani, Meredith A. Miller, Chiu-Yi Liu, Stella R. Hartono, Caleb A. Class, Christopher A. Bristow, Erika Suzuki, Lionel A. Sanz, Guang Gao, Jason P. Gay, Ningping Feng, Johnathon L. Rose, Hideo Tomihara, Joseph R. Daniele, Michael D. Peoples, Jennifer P. Bardenhagen, Mary K. Geck Do, Qing E. Chang, Bhavatarini Vangamudi, Christopher Vellano, Haoqiang Ying, Angela K. Deem, Kim-Anh Do, Giannicola Genovese, Joseph R. Marszalek, Jeffrey J. Kovacs, Michael Kim, Jason B. Fleming, Ernesto Guccione, Andrea Viale, Anirban Maitra, M. Emilia Di Francesco, Timothy A. Yap, Philip Jones, Giulio Draetta, Alessandro Carugo, Frederic Chedin, Timothy P. Heffernan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Arginine methylation by PRMTs is dysregulated in cancer. Here, the authors use functional genomics screens and identify PRMT1 as a vulnerability in pancreatic ductal adenocarcinoma, and further show that PRMT1 regulates RNA metabolism and coordinates
Externí odkaz:
https://doaj.org/article/a1a1a41f3dcc4a47a61b299fda338c49
Autor:
Jintan Liu, Sanjana Srinivasan, Chieh-Yuan Li, I-Lin Ho, Johnathon Rose, MennatAllah Shaheen, Gang Wang, Wantong Yao, Angela Deem, Chris Bristow, Traver Hart, Giulio Draetta
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
AsCpf1 is an alternative nuclease to Cas9 for CRISPR mediated genome engineering. Here the authors demonstrate functional genomic screens with AsCpf1 that minimize library size with no loss in gene targeting efficiency.
Externí odkaz:
https://doaj.org/article/302d4902b46145a7a871a5d3d6846970
Autor:
Dereddi Raja Reddy, John A. Cuenca, Joshua Botdorf, Mayoora Muthu, Ankit Hanmandlu, Robert Wegner, John Crommett, Cristina Gutierrez, Nisha Rathi, Bilja Sajith, Mark Knafl, Hussein A. Abbas, Scott E. Woodman, Joseph L. Nates, Ashley Aaroe, Thomas A. Aloia, Lee Andrews, Kiran K. Badami, Janna A. Baganz, Pratibha Bajwa, Lori R. Baker, Gregory R. Barbosa, Hannah C. Beird, Matt Bourgeois, Kristy Brock, Elizabeth M. Burton, Juan Cata, Caroline Chung, Michael Cutherell, Pierre B. Cyr, Bouthaina Dabaja, Hiba Dagher, Kevin M. Daniels, Mary Domask, Giulio Draetta, Sarah Fisher, Katy Elizabeth French, Andrew Futreal, Maria Gaeta, Christopher Gibbons, Myrna Godoy, Drew Goldstein, Jillian Gunther, Cristhiam Hernandez, Kate Hutcheson, David Jaffray, Jeff Jin, Teny Matthew John, Trey Kell, Anai Kothari, Rayson C. Kwan, J. Jack Lee, Yue Liao, Jennifer Litton, Alex Liu, Kevin W. McEnery, Mary McGuire, Tego Musunuru, Craig S. Owen, Priyadharshini Padmakumar, Melody Page, Nicholas Palaskas, Jay J. Patel, Sabitha Prabhakaran, Vinod Ravi, Ludivine Russell, Paul A. Scheet, Stephanie Schmidt, Kenna R. Shaw, Sanjay Shete, Daniel P. Shoenthal, Lessley J. Stoltenberg, Ishwaria Subbiah, Chuck Suitor, Hussein Tawbi, Phillip Thompson, Anastasia Turin, Samir Unni, Benju Vicknamparampil, Max C. Weber, John Weinstein, Zoe Williams, Mark C. Wozny, Carol Wu, Jia Wu, James C. Yao, Chingyi Young, Emily Yu, Steven Zatorski
Publikováno v:
Mayo Clinic Proceedings. 98:451-457
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0e4285ed56e25e2fcce40cf942510c3
https://doi.org/10.1016/j.mayocp.2022.12.008
https://doi.org/10.1016/j.mayocp.2022.12.008
Autor:
Gloria V. Echeverria, Emily Powell, Sahil Seth, Zhongqi Ge, Alessandro Carugo, Christopher Bristow, Michael Peoples, Frederick Robinson, Huan Qiu, Jiansu Shao, Sabrina L. Jeter-Jones, Xiaomei Zhang, Vandhana Ramamoorthy, Shirong Cai, Wenhui Wu, Giulio Draetta, Stacy L. Moulder, William F. Symmans, Jeffrey T. Chang, Timothy P. Heffernan, Helen Piwnica-Worms
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
It is unclear how intra-tumoral heterogeneity contributes to metastasis. Here the authors study the clonal dynamics of triple negative breast cancer metastasis using patient derived xenografts and demonstrate that primary tumor clones harbor properti
Externí odkaz:
https://doaj.org/article/d84938082d1647899042d8810ab7582c
Autor:
Raffaella Giavazzi, Alessandra Decio, MariaRosa Bani, Roberta Pastorelli, Christopher P. Vellano, Joseph R. Marszalek, Giulio Draetta, Giovanna Chiorino, Ferdinando Chiaradonna, Edoardo Arrigoni, Massimo Russo, Laura Formenti, Monica Salio, Fabio Fiordaliso, Alessia Anastasia, Monica Lupi, Nicolò Panini, Paola Ostano, Laura Brunelli, Catarina Moreira-Barbosa, Carmen Ghilardi
Supplementary Data from PGC1α/β Expression Predicts Therapeutic Response to Oxidative Phosphorylation Inhibition in Ovarian Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f1c9584e82750f0405461ab86d7abb3
https://doi.org/10.1158/0008-5472.22431307
https://doi.org/10.1158/0008-5472.22431307
Autor:
Raffaella Giavazzi, Alessandra Decio, MariaRosa Bani, Roberta Pastorelli, Christopher P. Vellano, Joseph R. Marszalek, Giulio Draetta, Giovanna Chiorino, Ferdinando Chiaradonna, Edoardo Arrigoni, Massimo Russo, Laura Formenti, Monica Salio, Fabio Fiordaliso, Alessia Anastasia, Monica Lupi, Nicolò Panini, Paola Ostano, Laura Brunelli, Catarina Moreira-Barbosa, Carmen Ghilardi
Ovarian cancer is the deadliest gynecologic cancer, and novel therapeutic options are crucial to improve overall survival. Here we provide evidence that impairment of oxidative phosphorylation (OXPHOS) can help control ovarian cancer progression, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a38fdfcb253d325749751c075e46f3e9
https://doi.org/10.1158/0008-5472.c.6513868.v1
https://doi.org/10.1158/0008-5472.c.6513868.v1
Autor:
Manfred Kraus, Jannik N. Andersen, Peter Blume-Jensen, Nancy Kohl, Victoria Richon, Giulio Draetta, Martin L. Scott, Roderick T. Bronson, Shailaja Kasibhatla, Ekaterina V. Bobkova, Alan Northrup, Thomas F. Vogt, Myung K. Shin, Melissa Hurd, Paula Andrade, Erica Leccese, Minilik Angagaw, Nirah H. Shomer, Diana Gargano, Alessandra Di Bacco, Yusuf Erkul, Erin O'Hare, Kumiko Nagashima, Kun Hu, Yamicia Connor, Brian Dolinski, Kaiko Kunii, Heike Keilhack, Katharine Ellwood-Yen
Supplementary Figures 1-4 from PDK1 Attenuation Fails to Prevent Tumor Formation in PTEN-Deficient Transgenic Mouse Models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::828919a62a5a02040e157eb5ac219fb4
https://doi.org/10.1158/0008-5472.22390089
https://doi.org/10.1158/0008-5472.22390089
Autor:
Jannik N. Andersen, Shikhar Sharma, Wylie S. Palmer, Philip Jones, Giulio Draetta, Dafydd R. Owen, Dominique Verhelle, Alessia Petrocchi, Carlo Toniatti, Joseph R. Marszalek, Timothy P. Heffernan, Mike Peoples, Trang N. Tieu, Andrew Futreal, Alexei Protopopov, Harshad S. Mahadeshwar, Elisabetta Leo, Yanai Zhan, Xi Shi, Lisa Nottebaum, Maria Kost-Alimova, Parantu K. Shah, Thomas A. Paul, Bhavatarini Vangamudi
Figure S1. Genomic analysis of SWI/SNF alterations in human cancer. Figure S2. SMARCA4-deficient lung cancer cells depend on SMARCA2 expression for growth. Figure S3. In-situ cell extraction assay for PFI-3 treatment. Figure S4. SMARCA2/4 bromodomain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ccf7d378c7bc490374b9266a8d53305
https://doi.org/10.1158/0008-5472.22407462.v1
https://doi.org/10.1158/0008-5472.22407462.v1
Autor:
Jannik N. Andersen, Shikhar Sharma, Wylie S. Palmer, Philip Jones, Giulio Draetta, Dafydd R. Owen, Dominique Verhelle, Alessia Petrocchi, Carlo Toniatti, Joseph R. Marszalek, Timothy P. Heffernan, Mike Peoples, Trang N. Tieu, Andrew Futreal, Alexei Protopopov, Harshad S. Mahadeshwar, Elisabetta Leo, Yanai Zhan, Xi Shi, Lisa Nottebaum, Maria Kost-Alimova, Parantu K. Shah, Thomas A. Paul, Bhavatarini Vangamudi
Supplementary Methods, Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0badb0679a64bcc92e6b33f08070943f
https://doi.org/10.1158/0008-5472.22407459
https://doi.org/10.1158/0008-5472.22407459
Autor:
Carmen Ghilardi, Catarina Moreira-Barbosa, Laura Brunelli, Paola Ostano, Nicolò Panini, Monica Lupi, Alessia Anastasia, Fabio Fiordaliso, Monica Salio, Laura Formenti, Massimo Russo, Edoardo Arrigoni, Ferdinando Chiaradonna, Giovanna Chiorino, Giulio Draetta, Joseph R. Marszalek, Christopher P. Vellano, Roberta Pastorelli, MariaRosa Bani, Alessandra Decio, Raffaella Giavazzi
Publikováno v:
Cancer Research. 82:1423-1434
Ovarian cancer is the deadliest gynecologic cancer, and novel therapeutic options are crucial to improve overall survival. Here we provide evidence that impairment of oxidative phosphorylation (OXPHOS) can help control ovarian cancer progression, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38021006f7cb288126f6b7e7ab5b1f5c
https://doi.org/10.1158/0008-5472.can-21-1223
https://doi.org/10.1158/0008-5472.can-21-1223