Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Giuliano Paglia"'
Autor:
Silvia Chichiarelli, Fabio Altieri, Giuliano Paglia, Elisabetta Rubini, Marco Minacori, Margherita Eufemi
Publikováno v:
Cellular & Molecular Biology Letters, Vol 27, Iss 1, Pp 1-18 (2022)
Abstract The ERp57/PDIA3 protein is a pleiotropic member of the PDIs family and, although predominantly located in the endoplasmic reticulum (ER), has indeed been found in other cellular compartments, such as the nucleus or the cell membrane. ERp57/P
Externí odkaz:
https://doaj.org/article/bcfc2c34886b4059be45759d4bd3f11b
Autor:
Giuliano Paglia, Marco Minacori, Giorgia Meschiari, Sara Fiorini, Silvia Chichiarelli, Margherita Eufemi, Fabio Altieri
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13279 (2023)
The protein disulfide isomerase A3 (PDIA3) is directly or indirectly involved in various physiopathological processes and participates in cancer initiation, progression and chemosensitivity. However, little is known about its involvement in glioblast
Externí odkaz:
https://doaj.org/article/26c0d9c453394fc39b6369919fb505b5
Autor:
Tommaso Cassano, Flavia Giamogante, Silvio Calcagnini, Adele Romano, Angelo Michele Lavecchia, Francesca Inglese, Giuliano Paglia, Vidyasagar Naik Bukke, Antonino Davide Romano, Marzia Friuli, Fabio Altieri, Silvana Gaetani
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 3005 (2023)
In the present study, we used a mouse model of Alzheimer’s disease (AD) (3×Tg-AD mice) to longitudinally analyse the expression level of PDIA3, a protein disulfide isomerase and endoplasmic reticulum (ER) chaperone, in selected brain limbic areas
Externí odkaz:
https://doaj.org/article/aa20019350ac41f4bd9ebafdc439a38f
Autor:
Elisabetta Rubini, Marco Minacori, Giuliano Paglia, Alberto Macone, Silvia Chichiarelli, Fabio Altieri, Margherita Eufemi
Publikováno v:
Molecules, Vol 26, Iss 23, p 7135 (2021)
The β-isomer of hexachlorocyclohexane (β-HCH) is a globally widespread pollutant that embodies all the physicochemical characteristics of organochlorine pesticides, constituting an environmental risk factor for a wide range of noncommunicable disea
Externí odkaz:
https://doaj.org/article/77f201b42976481487c7e988a28e27b3
Autor:
Giuliano Paglia, Lorenzo Antonini, Laura Cervoni, Rino Ragno, Manuela Sabatino, Marco Minacori, Elisabetta Rubini, Fabio Altieri
Publikováno v:
Biomedicines, Vol 9, Iss 11, p 1533 (2021)
In a previous work, it was shown that punicalagin, an active ingredient of pomegranate, is able to bind to PDIA3 and inhibit its disulfide reductase activity. Here we provide evidence that punicalagin can also bind to PDIA1, the main expressed form o
Externí odkaz:
https://doaj.org/article/30b42938319c4b4d99f6cd2368178aca
Autor:
Elisabetta Rubini, Marco Minacori, Giuliano Paglia, Fabio Altieri, Silvia Chichiarelli, Donatella Romaniello, Margherita Eufemi
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5834 (2021)
Organochlorine pesticides constitute the majority of the total environmental pollutants, and a wide range of compounds have been found to be carcinogenic to humans. Among all, growing interest has been focused on β-hexachlorocyclohexane (β-HCH), vi
Externí odkaz:
https://doaj.org/article/7f03b068faaf41fcb5f6c868e5f1c9bc
Autor:
Elisabetta Rubini, Giuliano Paglia, David Cannella, Alberto Macone, Antonella Di Sotto, Marco Gullì, Fabio Altieri, Margherita Eufemi
Publikováno v:
Biomedicines, Vol 8, Iss 11, p 505 (2020)
Organochlorine pesticides (OCPs) belong to a heterogeneous class of organic compounds blacklisted by the Stockholm Convention in 2009 due to their harmful impact on human health. Among OCPs, β-hexachlorocyclohexane (β-HCH) is one of the most widesp
Externí odkaz:
https://doaj.org/article/0cb8f94b090541728791a9bacec3485e
Autor:
Ilaria Marrocco, Fabio Altieri, Elisabetta Rubini, Giuliano Paglia, Silvia Chichiarelli, Flavia Giamogante, Alberto Macone, Giacomo Perugia, Fabio Massimo Magliocca, Aymone Gurtner, Bruno Maras, Rino Ragno, Alexandros Patsilinakos, Roberto Manganaro, Margherita Eufemi
Publikováno v:
Cells, Vol 8, Iss 9, p 1048 (2019)
Prostate cancer (PCa) is a multifactorial disease characterized by the aberrant activity of different regulatory pathways. STAT3 protein mediates some of these pathways and its activation is implicated in the modulation of several metabolic enzymes.
Externí odkaz:
https://doaj.org/article/ee257ac7494c4444ba09be9bb5988160
Autor:
Rossana Cocchiola, Elisabetta Rubini, Fabio Altieri, Silvia Chichiarelli, Giuliano Paglia, Donatella Romaniello, Stefania Carissimi, Alessandra Giorgi, Flavia Giamogante, Alberto Macone, Giacomo Perugia, Aymone Gurtner, Margherita Eufemi
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 8, p 1815 (2019)
STAT3 is an oncoprotein overexpressed in different types of tumors, including prostate cancer (PCa), and its activity is modulated by a variety of post-translational modifications (PTMs). Prostate cancer represents the most common cancer diagnosed in
Externí odkaz:
https://doaj.org/article/1f4cfb37a6e3487fa7e0792c368862ea
Autor:
Elisabetta Rubini, Fabio Altieri, Silvia Chichiarelli, Flavia Giamogante, Stefania Carissimi, Giuliano Paglia, Alberto Macone, Margherita Eufemi
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 7, p 2108 (2018)
Background: Organochlorine pesticides (OCPs) are widely distributed in the environment and their toxicity is mostly associated with the molecular mechanisms of endocrine disruption. Among OCPs, particular attention was focused on the effects of β-he
Externí odkaz:
https://doaj.org/article/eec6143b37434aa8ae1cd25c26cba719