Výsledky vyhledávání - "Giuliano Dodoni"

A toolkit for real-time detection of cAMP: insights into compartmentalized signaling

Autor: Ilaria Zamparo, Vanessa Pertegato, Manuela Zaccolo, Marco Berrera, Stefania Monterisi, Giuliano Dodoni

Publikováno v: Handbook of Experimental Pharmacology ISBN: 9783540728429

The study of cAMP signaling has received a renewed impulse since the recognition that a key aspect of this pathway is the tight spatial control of signal propagation. The study of the mechanism that regulates cAMP signaling in space and time has prom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9d4c131dbb303465f8402f2e775e28
https://doi.org/10.1007/978-3-540-72843-6_12

Zobrazit plný text záznamu

Formation of reactive oxygen species at increased contraction frequency in rat cardiomyocytes

Autor: Yukun Luo, Herbert de Groot, Fabio Di Lisa, Kerstin Boengler, Giuliano Dodoni, Frank R. Heinzel, Frank Petrat, Rainer Schulz, Gerd Heusch

Publikováno v: Cardiovascular Research. 71:374-382

Objective Reactive oxygen species (ROS) play an ambivalent role in cardiomyocytes: low concentrations are involved in cellular signaling, while higher concentrations contribute to cellular injury. We studied ROS formation during increases in contract

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b93607863339131a59134812842323e9
https://doi.org/10.1016/j.cardiores.2006.05.014

Zobrazit plný text záznamu

Cardiac Hypertrophy Is Inhibited by a Local Pool of cAMP Regulated by Phosphodiesterase 2

Publikováno v: Circulation research. 117(8)

Rationale : Chronic elevation of 3′-5′-cyclic adenosine monophosphate (cAMP) levels has been associated with cardiac remodeling and cardiac hypertrophy. However, enhancement of particular aspects of cAMP/protein kinase A signaling seems to be ben

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97658dd4c46b3d9c9366fedfeaece51
https://pubmed.ncbi.nlm.nih.gov/26243800

Zobrazit plný text záznamu

Induction of the mitochondrial permeability transition by the DNA alkylating agent N-methyl-N′-nitro-N-nitrosoguanidine. Sorting cause and consequence of mitochondrial dysfunction

Autor: Giuliano Dodoni, Valeria Petronilli, Fabio Di Lisa, Paolo Bernardi, Marcella Canton

Publikováno v: Università degli Studi di Padova-IRIS
Europe PubMed Central

The alkylating agent N -methyl- N ′-nitro- N -nitrosoguanidine (MNNG) alters DNA and stimulates the activity of poly(ADP-ribose) polymerase-1 (PARP-1), a nuclear enzyme involved in DNA repair. The consumption of cellular NAD + by PARP-1 is accompan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13532e789740c604f6d416fe51ffbd13
https://doi.org/10.1016/j.bbabio.2004.05.005

Zobrazit plný text záznamu

Mitochondrial dysfunction induced by a cytotoxic adenine dinucleotide produced by ADP-ribosyl cyclases from cADPR

Autor: Giuliano Dodoni, Antonio De Flora, Enrico Millo, Giovanna Basile, Nina Kaludercic, Fabio Di Lisa, Elena Zocchi, Santina Bruzzone

ADP-ribosyl cyclases were previously shown to produce three new adenine dinucleotides, P1,P2 diadenosine 5'-diphosphate (Ap2A) and two isomers thereof (P18 and P24), from cyclic ADP-ribose (cADPR) and adenine (Basile, G., Taglialatela-Scafati, O., Da

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7150069de4cc05378769fffb1e51ce7
http://hdl.handle.net/11567/286488

Zobrazit plný text záznamu

4-Hydroxymethyl-1,6,8-trimethylfuro [2,3-h] quinolin-2 (1H)-one induces mitochondrial dysfunction and apoptosis upon its intracellular oxidation

Autor: Marcella Canton, Christian Frezza, Vera Barbieri, Adriana Chilin, Adriano Guiotto, Fabio Di Lisa, Giuliano Dodoni

We investigated the mechanism of cell death induced by a furoquinolinone derivative, namely, 4-hydroxymethyl-1,6,8-trimethylfuro[2,3-h]quinolin-2(1H)-one (HOFQ), in the dark. Mitochondrial depolarization was found to be a causative event in HOFQ-indu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::829b0a08213cb500e098412c14998f21
http://hdl.handle.net/11577/2449258

Zobrazit plný text záznamu

Specific inhibition of monoamine oxidase A prevents oxidative stress in isolated mitochondria and HL-5 cardiomyoblasts

Autor: Nina Kaludercic, Andrea Carpi, Fabio Di Lisa, Giuliano Dodoni

Publikováno v: Journal of Molecular and Cellular Cardiology. 40:929

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8a4e943bc08669315f08c255dd8e6e16
https://doi.org/10.1016/j.yjmcc.2006.03.041

Zobrazit plný text záznamu

771 The opening of the permeability transition pore is responsible for mitochondrial dysfunction and cell death caused by N-methyl-N′-nitro-N-nitrosoguanidine (MNNG)

Autor: F. Di Lisa, Paolo Bernardi, Valeria Petronilli, Giuliano Dodoni

Publikováno v: European Journal of Heart Failure Supplements. 2:167

a.u. for control, p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bd692607b49828e578321beaaba9400b
https://doi.org/10.1016/s1567-4215(03)90507-8

Zobrazit plný text záznamu

Mitochondria and reperfusion injury. The role of permeability transition

Autor: Giuliano Dodoni, Roberta Menabò, Fabio Di Lisa, Paolo Bernardi, Marcella Canton

Publikováno v: Università degli Studi di Padova-IRIS
Scopus-Elsevier
Europe PubMed Central

The viability of the ischemic myocardium is jeopardized by alterations, such as ATP decrease and elevation in intracellular [Ca(2+)], that are related to derangements in mitochondrial function. Besides these established notions, the elucidation of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::941bc2e9640e9e143648216edca85376
https://www.research.unipd.it/handle/11577/2459912

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání