Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Giuliano Didio"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10249 (2022)
The activation of tropomyosin receptor kinase B (TrkB), the receptor of brain-derived neurotrophic factor (BDNF), plays a key role in induced juvenile-like plasticity (iPlasticity), which allows restructuring of neural networks in adulthood. Opticall
Externí odkaz:
https://doaj.org/article/613f7b929ed54147bd6d90c5931f8192
Autor:
Elias Jetsonen, Giuliano Didio, Frederike Winkel, Maria Llach Pou, Chloe Boj, Laura Kuczynski-Noyau, Vootele Võikar, Ramon Guirado, Tomi Taira, Sari E. Lauri, Eero Castrén, Juzoh Umemori
Publikováno v:
Neuropsychopharmacology. 48:1021-1030
SummaryCritical period-like plasticity (iPlasticity) can be reinstated in the adult brain by several interventions, including drugs and optogenetic modifications. We have demonstrated that a combination of iPlasticity with optimal training improves b
Autor:
Maria Llach Pou, Jonas Englund, Maria Ryazantseva, Stanislav Khirug, Sari E. Lauri, Antonia Lilja, Eero Castrén, Claudio Rivera, Anna Steinzeig, Mathias Benjamin Voigt, Juliana Harkki, Tomi Taira, Satu Palva, Frederike Winkel, Juzoh Umemori, Giuliano Didio
Publikováno v:
Molecular Psychiatry
Molecular Psychiatry, Nature Publishing Group, In press, ⟨10.1038/s41380-021-01211-0⟩
Molecular Psychiatry, Nature Publishing Group, In press, ⟨10.1038/s41380-021-01211-0⟩
Elevated states of brain plasticity typical for critical periods of early postnatal life can be reinstated in the adult brain through interventions, such as antidepressant treatment and environmental enrichment, and induced plasticity may be critical
Autor:
Maria Llach Pou, Buj C, Verie M, Ramon Guirado, Eero Castrén, Sari L, Tomi Taira, Juliana Harkki, Frederike Winkel, Giuliano Didio, Juzoh Umemori, Lo Russo G, Hanna Antila
Successful extinction of traumatic memories depends on neuronal plasticity in the fear extinction network. However, the mechanisms involved in the extinction process remain poorly understood. Here, we investigated the fear extinction network by using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40a9ddf167c6b5152c7d2ce51d3498de
https://doi.org/10.1101/2021.02.14.431126
https://doi.org/10.1101/2021.02.14.431126
Autor:
Sari E. Lauri, Frederike Winkel, Juzoh Umemori, Jonas Englund, Salome Mateo, Eero Castrén, Maria Llach Pou, Giuliano Didio, Stanislav Khirug, Mathias Benjamin Voigt, Claudio Rivera, Elias Jetsonen, Tomi Taira, Anna Steinzeig, Juliana Harkki, Satu Palva, Maria Ryazantseva
Activation state of Parvalbumin (PV) interneurons regulates neuronal plasticity, driving the closure of developmental critical periods and alternating between high and low plasticity states in response to experience in adulthood. We now show that PV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83820cd69b3ac515144e2592c6aa3f5b
https://doi.org/10.1101/2020.04.27.063503
https://doi.org/10.1101/2020.04.27.063503
Publikováno v:
Psychiatry and Clinical Neurosciences. 72:633-653
The network hypothesis of depression proposes that mood disorders reflect problems in information processing within particular neural networks. Antidepressants (AD), including selective serotonin reuptake inhibitors (SSRI), function by gradually impr
Publikováno v:
European Neuropsychopharmacology. 29:S20-S21
Publikováno v:
European Neuropsychopharmacology. 28:S12-S13
Brain network plasticity occurs principally during critical periods in early postnatal life [1]. Chronic treatment with the antidepressant fluoxetine, however, can induce critical period-like plasticity (iPlasticity), such as shift of ocular dominanc