Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Giuliano, Ciofani"'
Autor:
Domenico Lapenna, Francesco Cipollone, Ettore Porreca, Giuliano Ciofani, Antonio M. Calafiore
Publikováno v:
Free Radical Biology and Medicine. 124:525-531
We studied the specific enzymatic activities of selenium-dependent (GSH-Px) and -independent (GST-Px) glutathione peroxidase, glutathione reductase (GSSG-Red), and glutathione S-transferase (GST) in internal mammary arteries (IMArt) specimens obtaine
Autor:
Domenico Lapenna, Maria Adele Giamberardino, Ettore Porreca, Sante D. Pierdomenico, Giuliano Ciofani
Publikováno v:
Journal of Molecular and Cellular Cardiology. 114:328-333
Altered iron status may be relevant to the pathophysiology of aging. We have assessed redox-active catalytic low molecular weight iron (LMWI), non-heme iron (NHI), heme iron (HI), and total iron (TI) in the aerobically perfused hearts of aged rabbits
Publikováno v:
Experimental Gerontology. 91:34-38
It is not known whether aging alters glutathione metabolic status of the mammalian arterial tissue favoring vascular oxidative stress and dysfunction. Thus we assessed total, reduced and oxidized glutathione (TG, GSH and GSSG, respectively), the glut
Autor:
Giuliano Ciofani, Domenico Lapenna
Publikováno v:
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). 59
Chromium is a catalytic metal able to foster oxidant damage, albeit its capacity to induce human LDL oxidation is to date unkown. Thus, we have investigated whether trivalent and hexavalent chromium, namely Cr(III) and Cr(VI), can induce human LDL ox
Publikováno v:
Experimental Gerontology. 134:110871
Reductive stress, which is due to a paradoxical excess of antioxidants such as reduced glutathione (GSH) and GSH-related enzymes associated with decreased oxidant levels, has emerged as a pathogenetic mechanism of myocardial damage in pathological co
Autor:
Roberto Cotellese, Domenico Lapenna, Francesco Cipollone, Massimo Cieri, Sante D. Pierdomenico, Giuliano Ciofani, Gabriele Obletter, Ettore Porreca
Publikováno v:
Experimental gerontology. 116
It is not known whether aging alters the enzymatic reactive aldehyde- and lipid hydroperoxide-detoxifying capacity of the human arterial tissue favoring vascular oxidative stress. To address this issue, we studied the specific enzymatic activities of
Autor:
Sante Ucchino, Franco Cuccurullo, Carmine Di Ilio, Maria Adele Giamberardino, Giuliano Ciofani, Domenico Lapenna
Publikováno v:
Atherosclerosis. 238:190-194
Objective : To investigate enzymatic reactive aldehyde-scavenging enzyme capacity together with lipid peroxidation as expression of oxidative stress in atherosclerotic plaques of cigarette smokers and nonsmokers. Methods : We have assessed specific e
Autor:
Domenico Lapenna, Giovanni Davì, Giuliano Ciofani, Sante D. Pierdomenico, Maria Adele Giamberardino, Sante Ucchino
Publikováno v:
Clinical and experimental medicine. 18(1)
Bilirubin has protective effects against atherosclerotic cardiovascular diseases hypothetically due to its antioxidant–antilipoperoxidative properties. Thus, we investigated whether serum bilirubin is associated with oxidant damage, namely lipid pe
Publikováno v:
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). 41
Iron-induced human LDL oxidation, which is relevant to atherosclerosis, has not yet been properly investigated. We addressed such issue using iron(II) and (III) basically in the presence of phosphates, which are present in vivo and influence iron oxi
Autor:
Sante D. Pierdomenico, Domenico Lapenna, Franco Cuccurullo, Giuliano Ciofani, Chiara Cuccurullo
Publikováno v:
e-SPEN Journal. 7:e245-e248
Summary Background & aims We investigated the effects of twice daily oral supplementation with different ascorbic acid (AA) dosages and formulations on oxidative stress status and platelet biochemical function in type 2 diabetic patients (T2DP). Meth