Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Giuliana Metelli"'
Autor:
Enrico Tongiorgi, Arianna Sartori, Alessio Bratina, Paolo Manganotti, Alessio Polacchini, Giuliana Metelli
Publikováno v:
Research Journal of Neurology and Neuro Disorders. :05-18
Neuroprotection is considered a major therapeutic target in Multiple Sclerosis (MS), a chronic inflammatory demyelinating disease of the central nervous system (CNS). Accordingly, current disease modifying drugs (DMDs) for MS have been revaluated for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e7c8baf050d8a3c5874d5bf54ad760
https://doi.org/10.36811/rjnnd.2019.110002
https://doi.org/10.36811/rjnnd.2019.110002
Autor:
Gabriele Baj, Giuliana Metelli, Enrico Tongiorgi, L. Mascaretti, Ruggiero Francavilla, Marina Florean, Alessio Polacchini
Publikováno v:
Scientific Reports
Brain-Derived Neurotrophic Factor (BDNF) has attracted increasing interest as potential biomarker to support the diagnosis or monitor the efficacy of therapies in brain disorders. Circulating BDNF can be measured in serum, plasma or whole blood. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08bc85fe5bdf3fe14e3ddf77f5adf1eb
https://doi.org/10.1038/srep17989
https://doi.org/10.1038/srep17989
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 292(2)
Similar to ischemic preconditioning, diazoxide was documented to elicit beneficial bioenergetic consequences linked to cardioprotection. Inhibition of ATPase activity of mitochondrial F0F1ATP synthase may have a role in such effect and may involve th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d9cf9024ff28969a5a95a7db46b7ba0
https://pubmed.ncbi.nlm.nih.gov/17287451
https://pubmed.ncbi.nlm.nih.gov/17287451
Publikováno v:
Biochemical pharmacology. 67(10)
Diazoxide, a selective opener of the mitochondrial ATP-sensitive K+ channel (mitoK(ATP)), has been reported to enhance F(0)F(1)ATPsynthase inhibition during ischemia, but the underlying mechanisms are still unclear. Here, we demonstrate that diazoxid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674c9e09fa8bf5c58b73466d21f20928
https://pubmed.ncbi.nlm.nih.gov/15130761
https://pubmed.ncbi.nlm.nih.gov/15130761