Zobrazeno 1 - 5 of 5 pro vyhledávání: '"Giuliana, Ascone"'
1
Akademický článek
Fcγ receptor-mediated influx of S100A8/A9-producing neutrophils as inducer of bone erosion during antigen-induced arthritis
Autor: Irene Di Ceglie, Giuliana Ascone, Niels A. J. Cremers, Annet W. Sloetjes, Birgitte Walgreen, Thomas Vogl, Johannes Roth, J. Sjef Verbeek, Fons A. J. van de Loo, Marije I. Koenders, Peter M. van der Kraan, Arjen B. Blom, Martijn H. J. van den Bosch, Peter L. E. M. van Lent
Publikováno v: Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-15 (2018)
Abstract Background Osteoclast-mediated bone erosion is a central feature of rheumatoid arthritis (RA). Immune complexes, present in a large percentage of patients, bind to Fcγ receptors (FcγRs), thereby modulating the activity of immune cells. In
Externí odkaz: https://doaj.org/article/9d7253effde542e1a9c44878e23e232e
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2
Akademický článek
S100A8/A9 increases the mobilization of pro-inflammatory Ly6Chigh monocytes to the synovium during experimental osteoarthritis
Autor: Niels A. J. Cremers, Martijn H. J. van den Bosch, Stephanie van Dalen, Irene Di Ceglie, Giuliana Ascone, Fons van de Loo, Marije Koenders, Peter van der Kraan, Annet Sloetjes, Thomas Vogl, Johannes Roth, Edwin J. W. Geven, Arjen B. Blom, Peter L. E. M. van Lent
Publikováno v: Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-15 (2017)
Abstract Background Monocytes are dominant cells present within the inflamed synovium during osteoarthritis (OA). In mice, two functionally distinct monocyte subsets are described: pro-inflammatory Ly6Chigh and patrolling Ly6Clow monocytes. Alarmins
Externí odkaz: https://doaj.org/article/000ad2f4ec3f47dc9d28f7482a1ea756
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4
High LDL-C levels attenuate onset of inflammation and cartilage destruction in antigen-induced arthritis
Autor: Giuliana, Ascone, Irene, Di Ceglie, Martijn H J, van den Bosch, Nik N L, Kruisbergen, Birgitte, Walgreen, Annet W, Sloetjes, Ernst, Lindhout, Leo A B, Joosten, Fons A J, van de Loo, Marije I, Koenders, Peter M, van der Kraan, Arjen B, Blom, Peter L E M, van Lent
Publikováno v: Clinical and experimental rheumatology. 37(6)
In this study, we used hypercholesterolaemic apolipoprotein E-deficient (Apoe-/-) mice to investigate LDL/oxLDL effect on synovial inflammation and cartilage destruction during antigen-induced arthritis (AIA). Further, as macrophage FcγRs are crucia
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8e62def140861ede9fa72dde42a78788
https://pubmed.ncbi.nlm.nih.gov/31074720
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Plný text Recenzováno Digitální knihovna AV ČR
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