Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Giulia Varsano"'
Publikováno v:
Cell Reports, Vol 20, Iss 2, Pp 397-410 (2017)
Cell size homeostasis can be achieved by size checkpoints that couple cell size to cell-cycle progression or by alternative mechanisms such as constant extension. In mammalian cells, the existence of strict size checkpoints remains controversial due
Externí odkaz:
https://doaj.org/article/b63d80ca79cd42ae96cb30d180e9ffba
Publikováno v:
Communicative & Integrative Biology, Vol 10, Iss 4 (2017)
The maintenance of the epithelial architecture during tissue proliferation is achieved by apical positioning of the midbody after cell division. Consequently, midbody mislocalization contributes to epithelial architecture disruption, a fundamental ev
Externí odkaz:
https://doaj.org/article/32709408632a4c93992bc521700c2411
Autor:
Fernando Martín-Belmonte, Anne-Claude Gavin, Teresa Rubio, Marco L. Hennrich, Pablo Lujan, Britta Brügger, Timo Sachsenheimer, Giulia Varsano, Maja Köhn, Manuel Gálvez-Santisteban
Publikováno v:
Journal of Cell Science.
Disruption of epithelial architecture is a fundamental event during epithelial tumorigenesis. We show that the expression of the cancer-promoting phosphatase PRL-3 (PTP4A3), which is overexpressed in several epithelial cancers, in polarized epithelia
Autor:
Simona Polo, Oreste Segatto, Giulia Varsano, Stefano Alemà, Loriana Castellani, Elena Maspero, Costanza Ballarò, Yuri Frosi, Sergio Anastasi
Publikováno v:
The Journal of Cell Biology
The EGFR kinase inhibitor RALT/MIG6 also functions as an endocytic adaptor to promote receptor internalization by scaffolding AP-2 and intersectins.
Signaling by epidermal growth factor receptor (EGFR) must be controlled tightly because aberrant
Signaling by epidermal growth factor receptor (EGFR) must be controlled tightly because aberrant
Publikováno v:
Communicative & Integrative Biology, Vol 10, Iss 4 (2017)
Communicative & Integrative Biology
Communicative & Integrative Biology
The maintenance of the epithelial architecture during tissue proliferation is achieved by apical positioning of the midbody after cell division. Consequently, midbody mislocalization contributes to epithelial architecture disruption, a fundamental ev
Autor:
Maja Köhn, Christoph Meyer, Xun Li, Victoria J. McParland, Janet M. Thornton, Karolina Pavic, Giulia Varsano, Pablo Rios, Ajay Aravind, Jancy Baby
Publikováno v:
Biochemistry. 50(35)
Phosphatase of regenerating liver 3 (PRL-3) is suggested as a biomarker and therapeutic target in several cancers. It has a well-established causative role in cancer metastasis. However, little is known about its natural substrates, pathways, and bio