Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Giulia Sheftel"'
Autor:
Herbert M. Lachman, Aelred Boyle, Manisha Juthani, Giulia Sheftel, Demitri F. Papolos, Emmelene Edwards, Fritz A. Henn
Publikováno v:
Brain Research. 609:110-116
Glucocorticoids (GC) have an important effect on mood in humans and influence learned helplessness, an escape avoidance paradigm that is considered one of the best animal models of depression. A strong genetic component underlies the development of l
Autor:
A. Boyle, Herbert M. Lachman, Giulia Sheftel, M. M. Divish, Vasundhara D. Kalasapudi, Demitri F. Papolos
Publikováno v:
Journal of neuroscience research. 28(1)
Lithium salts are the most effective agents used in treating manic-depressive illness. It has been suggested that lithium's therapeutic efficacy could be due to an inhibitory effect on either inositol phospholipid (IP) and/or cyclic nucleotide metabo
Autor:
Vasundhara D. Kalasapudi, Giulia Sheftel, Margaret M. Divish, Demitri F. Papolos, Herbert M. Lachman
Publikováno v:
Brain research. 521(1-2)
It has been proposed that lithium's antimanic action is due to an effect on phosphoinositide metabolism. Second messengers generated by this pathway regulate calcium mobilization and the activity of the serine and threonine kinase, protein kinase C (
Autor:
T. H. M. Ottenhoff, P Converse, M. Dietz, Giulia Sheftel, M. Becx‐Bleumink, Gilla Kaplan, S Teklemariam, G E Hancock, C. K. Job, R Kiessling
Publikováno v:
The Journal of Experimental Medicine
Human rIL-2 (10-30 micrograms) was injected intradermally into the skin of patients with lepromatous leprosy with high bacillary loads. All patients responded to the lymphokine with local areas of induration that peaked at 24 h and persisted for 4-7
Autor:
R. S. Mishra, Suman Laal, Indira Nath, Asma Nusrat, Zanvil A. Cohn, Gilla Kaplan, Giulia Sheftel, N. K. Mathur
Publikováno v:
The Journal of Experimental Medicine
We have analyzed the nature and kinetics of a delayed, cell-mediated immune response to a purified protein derivative of tuberculin (PPD) in the skin of 154 naturally sensitized patients with lepromatous leprosy. After the intradermal injection of 5
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 85(14)
The purpose of this study was to evaluate the effects of a delayed-type cell-mediated immune response to Mycobacterium tuberculosis antigen on the Mycobacterium leprae load in the skin of leprosy patients. Twelve patients with the lepromatous form of