Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Giulia Sbrini"'
Autor:
Giulia Sbrini, Zaira Tomasoni, Maria Rosa Cutrì, Alba Pilotta, Chiara Mingotti, Raffaele Badolato, Luca La Via, Alessandro Barbon, Federica Bono, Chiara Fiorentini
Publikováno v:
Stem Cell Research, Vol 74, Iss , Pp 103293- (2024)
We have established Noonan syndrome (NS)-derived induced pluripotent stem cell (iPSC) lines derived from peripheral blood mononuclear cells (PBMCs) of a family cohort carrying the heterozygous PTPN11 c.188 A > G (p.Y63C) mutation. The new iPSC lines
Externí odkaz:
https://doaj.org/article/aee40349e31e43ecb048ec38c4a60166
Autor:
Federica Bono, Chiara Fiorentini, Veronica Mutti, Zaira Tomasoni, Giulia Sbrini, Hanna Trebesova, Mario Marchi, Massimo Grilli, Cristina Missale
Publikováno v:
Pharmacological Research, Vol 190, Iss , Pp 106711- (2023)
Neuronal nicotinic acetylcholine receptors (nAChRs) are widely distributed in both the peripheral and the central nervous systems. nAChRs exert a crucial modulatory influence on several brain biological processes; they are involved in a variety of ne
Externí odkaz:
https://doaj.org/article/dc9ca083b90e46e6b1c428ebf02756a5
Autor:
Federica Bono, Zaira Tomasoni, Veronica Mutti, Giulia Sbrini, Rajesh Kumar, Francesca Longhena, Chiara Fiorentini, Cristina Missale
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 473 (2023)
The heteromer composed of dopamine D1 and D3 receptors (D1R–D3R) has been defined as a structure able to trigger Erk1/2 and Akt signaling in a G protein-independent, beta-arrestin 1-dependent way that is physiologically expressed in the ventral str
Externí odkaz:
https://doaj.org/article/76a9ea414bce4f11a1453414dea625a0
Autor:
Giulia Sbrini, Paola Brivio, Polina Mineva Peeva, Mihail Todiras, Michael Bader, Natalia Alenina, Francesca Calabrese
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Alterations in serotonergic transmission have been related to a major predisposition to develop psychiatric pathologies, such as depression. We took advantage of tryptophan hydroxylase (TPH) 2 deficient rats, characterized by a complete absence of se
Externí odkaz:
https://doaj.org/article/9f14fe125055426c83c9703d7907b743
Autor:
Giulia Sbrini, Paola Brivio, Enrico Sangiovanni, Marco Fumagalli, Giorgio Racagni, Mario Dell’Agli, Francesca Calabrese
Publikováno v:
Biomedicines, Vol 8, Iss 12, p 544 (2020)
Brain derived neurotrophic factor (Bdnf) is the most diffuse neurotrophin in the central nervous system and it is crucial for the proper brain development and maintenance. Indeed, through the binding to its high affinity receptor TRKB and the activat
Externí odkaz:
https://doaj.org/article/923933dd1d024f9180fbdffcbd595e12
Autor:
Paola Brivio, Giulia Sbrini, Polina Peeva, Mihail Todiras, Michael Bader, Natalia Alenina, Francesca Calabrese
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Dysregulations of the central serotoninergic system have been implicated in several psychopathologies, characterized by different susceptibility between males and females. We took advantage of tryptophan hydroxylase 2 (TPH2) deficient rats, lacking s
Externí odkaz:
https://doaj.org/article/f3af7ac4c2f1428080cb6e4d5db47d7a
Autor:
Xianzong Meng, Joanes Grandjean, Giulia Sbrini, Pieter Schipper, Nita Hofwijks, Francesca Calabrese, Judith Homberg
The central serotoninergic system is critical for stress responsivity and social behavior, and its dysregulations has been centrally implicated in virtually all neuropsychiatric disorders. Genetic serotonin depletion animal models could provide a too
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4dc851efae2677fa6ee03348334e0d5
https://doi.org/10.1101/2022.07.08.499134
https://doi.org/10.1101/2022.07.08.499134
Autor:
Federica, Bono, Veronica, Mutti, Zaira, Tomasoni, Giulia, Sbrini, Cristina, Missale, Chiara, Fiorentini
Publikováno v:
Current topics in behavioral neurosciences. 60
G protein-coupled receptors (GPCR) heterodimers represent new entities with unique pharmacological, signalling, and trafficking properties, with specific distribution restricted to those cells where the two interacting receptors are co-expressed. Lik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5e823c7f4c12cdba784a7b4d2c420069
https://pubmed.ncbi.nlm.nih.gov/35505059
https://pubmed.ncbi.nlm.nih.gov/35505059
Autor:
Calabrese, Giulia Sbrini, Sabrina I. Hanswijk, Paola Brivio, Anthonieke Middelman, Michael Bader, Fabio Fumagalli, Natalia Alenina, Judith R. Homberg, Francesca
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 4941
Serotonin is synthetized through the action of tryptophan hydroxylase (TPH) enzymes. While the TPH2 isoform is responsible for the production of serotonin in the brain, TPH1 is expressed in peripheral organs. Interestingly, despite its peripheral loc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::e6123809552915c4df7c269d01d52941
Autor:
Giulia, Sbrini, Sabrina I, Hanswijk, Paola, Brivio, Anthonieke, Middelman, Michael, Bader, Fabio, Fumagalli, Natalia, Alenina, Judith R, Homberg, Francesca, Calabrese
Publikováno v:
International journal of molecular sciences. 23(9)
Serotonin is synthetized through the action of tryptophan hydroxylase (TPH) enzymes. While the TPH2 isoform is responsible for the production of serotonin in the brain, TPH1 is expressed in peripheral organs. Interestingly, despite its peripheral loc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::991f194e3b5fa6a0863af2f73b026331
https://pubmed.ncbi.nlm.nih.gov/35563331
https://pubmed.ncbi.nlm.nih.gov/35563331