Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Giulia Ruzzante"'
Autor:
Thomas Hoyler, Bettina Bannert, Cédric André, Damian Beck, Thomas Boulay, David Buffet, Nadja Caesar, Thomas Calzascia, Janet Dawson, Diego Kyburz, Robert Hennze, Christine Huppertz, Amanda Littlewood-Evans, Pius Loetscher, Kirsten D. Mertz, Satoru Niwa, Gautier Robert, James S. Rush, Giulia Ruzzante, Sophie Sarret, Thomas Stein, Ismahane Touil, Grazyna Wieczorek, Geraldine Zipfel, Stuart Hawtin, Tobias Junt
Publikováno v:
JCI Insight, Vol 7, Iss 13 (2022)
IL-1 receptor-activated kinase 1 (IRAK1) is involved in signal transduction downstream of many TLRs and the IL-1R. Its potential as a drug target for chronic inflammatory diseases is underappreciated. To study its functional role in joint inflammatio
Externí odkaz:
https://doaj.org/article/6fc6e2c6d008483f99d660e2370be0ce
Autor:
Claudia Betschart, Michael Faller, Florence Zink, René Hemmig, Jutta Blank, Eric Vangrevelinghe, Marjorie Bourrel, Ralf Glatthar, Dirk Behnke, Kerstin Barker, Andreas Heizmann, Daniela Angst, Pierre Nimsgern, Sébastien Jacquier, Tobias Junt, Géraldine Zipfel, Giulia Ruzzante, Pius Loetscher, Sarah Limonta, Stuart Hawtin, Cedric Bernard Andre, Thomas Boulay, Roland Feifel, Thomas Knoepfel
Publikováno v:
ACS Med Chem Lett
[Image: see text] Inappropriate activation of TLR7 and TLR8 is linked to several autoimmune diseases, such as lupus erythematosus. Here we report on the efficient structure-based optimization of the inhibition of TLR8, starting from a co-crystal stru
Autor:
Stuart Hawtin, Cédric André, Géraldine Collignon-Zipfel, Simone Appenzeller, Bettina Bannert, Lea Baumgartner, Damian Beck, Claudia Betschart, Thomas Boulay, Hermine I. Brunner, Melanie Ceci, Jonathan Deane, Roland Feifel, Enrico Ferrero, Diego Kyburz, Frederique Lafossas, Pius Loetscher, Christina Merz-Stoeckle, Pierre Michellys, Barbara Nuesslein-Hildesheim, Friedrich Raulf, James S. Rush, Giulia Ruzzante, Thomas Stein, Samantha Zaharevitz, Grazyna Wieczorek, Richard Siegel, Peter Gergely, Tamas Shisha, Tobias Junt
Publikováno v:
Cell Reports Medicine. 4:101036
Autor:
Thore Thiesler, Alessandro Lugli, Lukas F. Mager, Viktor H. Koelzer, Inti Zlobec, Tobias Junt, Gieri Cathomas, Marie-Hélène Wasmer, Holger Moch, Jenna R. Murdoch, Giulia Ruzzante, Achim Weber, Stefanie Joller, Kirsten D. Mertz, Philippe Krebs, Thomas Brümmendorf, Vera Genitsch
Publikováno v:
OncoImmunology
Mertz, Kirsten D; Mager, Lukas F.; Wasmer, Marie-Hélène; Thiesler, Thore; Kölzer, Viktor H.; Ruzzante, Giulia; Joller, Stefanie; Murdoch, Jenna R; Brümmendorf, Thomas; Genitsch Gratwohl, Vera; Lugli, Alessandro; Cathomas, Gieri; Moch, Holger; Weber, Achim; Zlobec, Inti; Junt, Tobias; Krebs, Philippe (2016). The IL-33/ST2 pathway contributes to intestinal tumorigenesis in humans and mice. Oncoimmunology, 5(1), e1062966. Landes Bioscience 10.1080/2162402X.2015.1062966
Oncoimmunology
Mertz, Kirsten D; Mager, Lukas F.; Wasmer, Marie-Hélène; Thiesler, Thore; Kölzer, Viktor H.; Ruzzante, Giulia; Joller, Stefanie; Murdoch, Jenna R; Brümmendorf, Thomas; Genitsch Gratwohl, Vera; Lugli, Alessandro; Cathomas, Gieri; Moch, Holger; Weber, Achim; Zlobec, Inti; Junt, Tobias; Krebs, Philippe (2016). The IL-33/ST2 pathway contributes to intestinal tumorigenesis in humans and mice. Oncoimmunology, 5(1), e1062966. Landes Bioscience 10.1080/2162402X.2015.1062966
Oncoimmunology
Colorectal cancer (CRC) develops through a multistep process and is modulated by inflammation. However, the inflammatory pathways that support intestinal tumors at different stages remain incompletely understood. Interleukin (IL)-33 signaling plays a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a6a9902d6e72acedf968d5930b7020
Autor:
Stephen M. Beverley, Silvia A. Fuertes-Marraco, Lon-Fye Lye, Giulia Ruzzante, Mélanie Revaz-Breton, Suzanne M. Hickerson, Haroun Zangger, Florence Prevel, Catherine Ronet, Nicolas Fasel, Slavica Masina, Pascal Launois, Frédéric Schütz, Hans Acha-Orbea, Annette Ives
Publikováno v:
Science, vol. 331, no. 6018, pp. 775-778
Science (New York N.Y.)
Science (New York N.Y.)
Mucocutaneous leishmaniasis is caused by infections with intracellular parasites of the Leishmania Viannia subgenus, including Leishmania guyanensis. The pathology develops after parasite dissemination to nasopharyngeal tissues, where destructive met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b798ff98dc10c23a73df16225357c2b5
https://serval.unil.ch/notice/serval:BIB_8FAE2070D6E0
https://serval.unil.ch/notice/serval:BIB_8FAE2070D6E0