Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Giulia Refolo"'
Autor:
Veronica Bordoni, Eleonora Tartaglia, Giulia Refolo, Alessandra Sacchi, Germana Grassi, Andrea Antinori, Gian Maria Fimia, Chiara Agrati
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Chronic HIV infection accelerates immune aging and is associated with abnormal hemato-lymphopoiesis, but the relationship between HIV-induced aging and Hematopoietic Progenitor Cells (HPC) function is not well-defined. In the context of aging, it has
Externí odkaz:
https://doaj.org/article/63f68cb2df6447398047e1251afdb5d9
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
In the last years, proteomics has represented a valuable approach to elucidate key aspects in the regulation of type I/III interferons (IFNs) and autophagy, two main processes involved in the response to viral infection, to unveil the molecular strat
Externí odkaz:
https://doaj.org/article/33a84f31791543f08b3336461fb9b8c1
Autor:
Fabiola Ciccosanti, Marco Corazzari, Rita Casetti, Alessandra Amendola, Diletta Collalto, Giulia Refolo, Alessandra Vergori, Chiara Taibi, Gianpiero D’Offizi, Andrea Antinori, Chiara Agrati, Gian Maria Fimia, Giuseppe Ippolito, Mauro Piacentini, Roberta Nardacci
Publikováno v:
Cells, Vol 10, Iss 5, p 1207 (2021)
Autophagy is a lysosomal-dependent degradative mechanism essential in maintaining cellular homeostasis, but it is also considered an ancient form of innate eukaryotic fighting against invading microorganisms. Mounting evidence has shown that HIV-1 is
Externí odkaz:
https://doaj.org/article/24a376728fb6434da3ff91336757b53b
Autor:
Carmine Mancone, Alessio Grimaldi, Giulia Refolo, Isabella Abbate, Gabriella Rozera, Dario Benelli, Gian Maria Fimia, Vincenzo Barnaba, Marco Tripodi, Mauro Piacentini, Fabiola Ciccosanti
Publikováno v:
Proteome Science, Vol 15, Iss 1, Pp 1-10 (2017)
Abstract Background Changes in iron metabolism frequently accompany HIV-1 infection. However, while many clinical and in vitro studies report iron overload exacerbates the development of infection, many others have found no correlation. Therefore, th
Externí odkaz:
https://doaj.org/article/dcf8572bc4504a9faab927f815a79f1f
Autor:
Tiziana Vescovo, Giulia Refolo, Matteo Ciancio Manuelli, Giuseppe Tisone, Mauro Piacentini, Gian Maria Fimia
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Statins efficiently inhibit cholesterol synthesis by blocking 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase in the mevalonate pathway. However, the effect of statins on intracellular cholesterol is partially counterbalanced by a consequent increased
Externí odkaz:
https://doaj.org/article/ab0e24a3ca254919937cc2f9677936c9
Autor:
Manuela D’Eletto, Federica Rossin, Luca Occhigrossi, Maria Grazia Farrace, Danilo Faccenda, Radha Desai, Saverio Marchi, Giulia Refolo, Laura Falasca, Manuela Antonioli, Fabiola Ciccosanti, Gian Maria Fimia, Paolo Pinton, Michelangelo Campanella, Mauro Piacentini
Publikováno v:
Cell Reports, Vol 25, Iss 13, Pp 3573-3581.e4 (2018)
Summary: Transglutaminase type 2 (TG2) is a multifunctional enzyme that plays a key role in mitochondria homeostasis under stressful cellular conditions. TG2 interactome analysis reveals an enzyme interaction with GRP75 (glucose-regulated protein 75)
Externí odkaz:
https://doaj.org/article/a83291863d9942ff9278c205e58a4ea1
Autor:
Giuseppe Arena, Mauro Piacentini, Veronica Consalvi, Fabiola Ciccosanti, Gian Maria Fimia, Martina Di Rienzo, Alessandra Romagnoli, Enza Maria Valente, Giulia Refolo
Publikováno v:
Autophagy. 18(8)
PINK1 accumulation at the outer mitochondrial membrane (OMM) is a key event required to signal depolarized mitochondria to the autophagy machinery. How this early step is, in turn, modulated by autophagy proteins remains less characterized. Here, we
Autor:
Andrea Antinori, Alessandra Vergori, Roberta Nardacci, Chiara Taibi, Gian Maria Fimia, Gianpiero D'Offizi, Diletta Collalto, Alessandra Amendola, Giuseppe Ippolito, Rita Casetti, Giulia Refolo, Chiara Agrati, Marco Corazzari, Fabiola Ciccosanti, Mauro Piacentini
Publikováno v:
Cells
Cells, Vol 10, Iss 1207, p 1207 (2021)
Volume 10
Issue 5
Cells, Vol 10, Iss 1207, p 1207 (2021)
Volume 10
Issue 5
Autophagy is a lysosomal-dependent degradative mechanism essential in maintaining cellular homeostasis, but it is also considered an ancient form of innate eukaryotic fighting against invading microorganisms. Mounting evidence has shown that HIV-1 is
Autor:
Lorenzo Botta, Fabiola Ciccosanti, Francesca Colavita, Gian Maria Fimia, Fabrizio Manetti, Martina Di Rienzo, Concetta Castilletti, Alessandra Romagnoli, Giuseppe Ippolito, Annalaura Brai, Giulia Refolo, Mauro Piacentini, Maria Rosaria Capobianchi, Chiara Agrati
Publikováno v:
Antiviral Research
COVID-19 is currently a highly pressing health threat and therapeutic strategies to mitigate the infection impact are urgently needed. Characterization of the SARS-CoV-2 interactome in infected cells may represent a powerful tool to identify cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::217b3ebf478516ed3ffc9ca4461d86b2
http://hdl.handle.net/11573/1572508
http://hdl.handle.net/11573/1572508
Autor:
Fulvio Reggiori, Monica Dentice, Marcella Neri, Manuela Antonioli, M. Di Rienzo, Idil Orhon, Fabiola Ciccosanti, Alessandra Ferlini, Giuseppe Merla, F. Germani, Mauro Piacentini, Barbara Mandriani, H. Ding, Giulia Refolo, Muriel Mari, Maria Teresa Pellico, Marco Corazzari, Molly Kulesz-Martin, Carmela Fusco, Gian Maria Fimia, Yuangang Liu, Alessandra Romagnoli, R. De La Torre
Publikováno v:
Science Advances, 5(5):8857. AMER ASSOC ADVANCEMENT SCIENCE
Di Rienzo, M, Antonioli, M, Fusco, C, Liu, Y, Mari, M, Orhon, I, Refolo, G, Germani, F, Corazzari, M, Romagnoli, A, Ciccosanti, F, Mandriani, B, Pellico, M T, De La Torre, R, Ding, H, Dentice, M, Neri, M, Ferlini, A, Reggiori, F, Kulesz-Martin, M, Piacentini, M, Merla, G & Fimia, G M 2019, ' Autophagy induction in atrophic muscle cells requires ULK1 activation by TRIM32 through unanchored K63-linked polyubiquitin chains ', Science Advances, vol. 5, no. 5, pp. eaau8857 . https://doi.org/10.1126/sciadv.aau8857
Science Advances
Di Rienzo, M, Antonioli, M, Fusco, C, Liu, Y, Mari, M, Orhon, I, Refolo, G, Germani, F, Corazzari, M, Romagnoli, A, Ciccosanti, F, Mandriani, B, Pellico, M T, De La Torre, R, Ding, H, Dentice, M, Neri, M, Ferlini, A, Reggiori, F, Kulesz-Martin, M, Piacentini, M, Merla, G & Fimia, G M 2019, ' Autophagy induction in atrophic muscle cells requires ULK1 activation by TRIM32 through unanchored K63-linked polyubiquitin chains ', Science Advances, vol. 5, no. 5, pp. eaau8857 . https://doi.org/10.1126/sciadv.aau8857
Science Advances
Muscular dystrophy-associated mutations of TRIM32 impair ULK1-dependent autophagy response during muscle atrophy.
Optimal autophagic activity is crucial to maintain muscle integrity, with either reduced or excessive levels leading to specific my
Optimal autophagic activity is crucial to maintain muscle integrity, with either reduced or excessive levels leading to specific my
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc5e5ef1f7060187c8321286a480b01
https://research.rug.nl/en/publications/4b803b6d-cd0a-4b3a-afe8-faf8661628fd
https://research.rug.nl/en/publications/4b803b6d-cd0a-4b3a-afe8-faf8661628fd