Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Giulia Rainoldi"'
Autor:
Giulia Rainoldi
Publikováno v:
Itinera, Iss 23 (2022)
Since Virtual Reality (VR) is characterised by the absence of the frame, the VR user has the impression of being immersed into the image, thus overcoming the distinction between spectacle and spectator. Therefore, the user becomes herself part of the
Externí odkaz:
https://doaj.org/article/3995f7ad84fe4170a6e081ab31a2b2ee
Publikováno v:
Molecules, Vol 22, Iss 11, p 2016 (2017)
This work describes the synthesis of enantioenriched spiro compounds, incorporating the azetidine and the oxindole motifs. The preparation relies on a formal [2 + 2] annulation reaction of isatin-derived N-tert-butylsulfonyl ketimines with allenoates
Externí odkaz:
https://doaj.org/article/9fa68edf422c4fb6999adc32a4995498
Publikováno v:
RSC Advances. 8:34903-34910
A multicomponent Ugi reaction involving isatin, isocyanide and β-amino acid components has been developed. The reactions proceeded smoothly to give β-lactam-containing 3,3-disubstituted oxindoles in only one step and generally high yields. When chi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630f276ef1b868f43cebf3d542264642
https://doi.org/10.1039/c8ra08165d
https://doi.org/10.1039/c8ra08165d
Publikováno v:
Expert opinion on drug discovery. 14(7)
Introduction: Multicomponent reactions are paramount in drug discovery for their ability to achieve high levels of diversity within the chemical space, generating complex structures from simple building blocks. Among them, the isocyanide-based Ugi-Jo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726f2ed85205ae30b091d690126605d1
https://pubmed.ncbi.nlm.nih.gov/31002536
https://pubmed.ncbi.nlm.nih.gov/31002536
Publikováno v:
Synlett. 27:2831-2835
A one-pot, three-component reaction has been developed and successfully employed for the synthesis of biologically relevant, highly functionalized spirooxindole-fused 3-thiazoline derivatives. Starting from ammonia, three mercapto carbonyl components
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6ae7725ce31dce0ab70d0277b3aedc6
https://doi.org/10.1055/s-0036-1589286
https://doi.org/10.1055/s-0036-1589286
Autor:
Fiorella Meneghetti, Alessandra Silvani, Giordano Lesma, Alessandro Sacchetti, Mattia Stucchi, Giulia Rainoldi
Publikováno v:
The Journal of Organic Chemistry. 81:1877-1884
The first asymmetric, Brønsted acid catalyzed Biginelli-like reaction of a ketone has been developed, employing N-substituted isatins as carbonyl substrates, and urea and alkyl acetoacetates as further components. BINOL-derived phosphoric acid catal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b634eed527152bfbc1b437c865a0cbd
https://doi.org/10.1021/acs.joc.5b02680
https://doi.org/10.1021/acs.joc.5b02680
Publikováno v:
Organic & Biomolecular Chemistry. 14:7768-7776
A family of chiral quaternary 3-aminooxindole butenolides has been synthesized by BINOL-derived phosphoric acid-catalyzed addition of trimethylsiloxyfuran to isatin-derived ketimines. Such a vinylogous Mannich-type reaction was found to produce diast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::515da3ab62ad382b1846d507ac1697d4
https://doi.org/10.1039/c6ob01359g
https://doi.org/10.1039/c6ob01359g
Autor:
Giampietro Viola, Gabriella Roda, Alessandra Silvani, Daniela Ubiali, Giordano Lesma, Andrea Luraghi, Giulia Rainoldi, Roberta Bortolozzi, Teodora Bavaro
Publikováno v:
Journal of natural products. 81(10)
Fifteen new multifunctional conjugates were designed and synthesized by chemically linking the steroidal framework of natural occurring γ-oryzanol and γ-oryzanol-derived phytosterols to a wide range of bioactive natural compounds (fatty acids, phen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e020f67448ce2acfa21c698474db87
https://pubmed.ncbi.nlm.nih.gov/30360625
https://pubmed.ncbi.nlm.nih.gov/30360625
Autor:
Alessandra Silvani, Mariska De Munnik, Giulia Rainoldi, Fabio Begnini, Eelco Ruijter, Romano V. A. Orru, Leonardo Lo Presti, Giordano Lesma, Christophe M. L. Vande Velde
Publikováno v:
Rainoldi, G, Begnini, F, De Munnik, M, Lo Presti, L, Vande Velde, C M L, Orru, R, Lesma, G, Ruijter, E & Silvani, A 2018, ' Sequential Multicomponent Strategy for the Diastereoselective Synthesis of Densely Functionalized Spirooxindole-Fused Thiazolidines ', ACS Combinatorial Science, vol. 20, no. 2, pp. 98-105 . https://doi.org/10.1021/acscombsci.7b00179
ACS combinatorial science
ACS Combinatorial Science, 20(2), 98-105. American Chemical Society
ACS combinatorial science
ACS Combinatorial Science, 20(2), 98-105. American Chemical Society
We developed two Ugi-type three-component reactions of spirooxindole-fused 3-thiazolines, isocyanides, and either carboxylic acids or trimethylsilyl azide, to give highly functionalized spirooxindole-fused thiazolidines. Two diverse libraries were ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1540f0a341547c3a4c6a7efe3aaf8f15
https://research.vu.nl/en/publications/044abadd-7ca8-4850-95b7-466d91819aed
https://research.vu.nl/en/publications/044abadd-7ca8-4850-95b7-466d91819aed
Publikováno v:
Molecules, 22(11):2016. Multidisciplinary Digital Publishing Institute (MDPI)
Rainoldi, G, Faltracco, M, Spatti, C, Silvani, A & Lesma, G 2017, ' Organocatalytic access to enantioenriched spirooxindole-based 4-methyleneazetidines ', Molecules, vol. 22, no. 11, 2016 . https://doi.org/10.3390/molecules22112016
Molecules; Volume 22; Issue 11; Pages: 2016
Molecules, Vol 22, Iss 11, p 2016 (2017)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Rainoldi, G, Faltracco, M, Spatti, C, Silvani, A & Lesma, G 2017, ' Organocatalytic access to enantioenriched spirooxindole-based 4-methyleneazetidines ', Molecules, vol. 22, no. 11, 2016 . https://doi.org/10.3390/molecules22112016
Molecules; Volume 22; Issue 11; Pages: 2016
Molecules, Vol 22, Iss 11, p 2016 (2017)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
This work describes the synthesis of enantioenriched spiro compounds, incorporating the azetidine and the oxindole motifs. The preparation relies on a formal [2 + 2] annulation reaction of isatin-derived N-tert-butylsulfonyl ketimines with allenoates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107b74acd33eeb7ad02a503e9fffecea
https://research.vu.nl/en/publications/54d67346-c5a7-4472-90dd-97d53ad37613
https://research.vu.nl/en/publications/54d67346-c5a7-4472-90dd-97d53ad37613