Short-term treatment with eicosapentaenoic acid improves inflammation and affects colonic differentiation markers and microbiota in patients with ulcerative colitis

Autor: Anna Prossomariti, Eleonora Scaioli, Giulia Piazzi, Chiara Fazio, Matteo Bellanova, Elena Biagi, Marco Candela, Patrizia Brigidi, Clarissa Consolandi, Tiziana Balbi, Pasquale Chieco, Alessandra Munarini, Milena Pariali, Manuela Minguzzi, Franco Bazzoli, Andrea Belluzzi, Luigi Ricciardiello

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)

Abstract Patients with long-standing ulcerative colitis (UC) have an increased colorectal cancer (CRC) risk. In this pilot study we evaluated the effect of Eicosapentaenoic acid as free fatty acid (EPA-FFA) supplementation on mucosal disease activity

Externí odkaz: https://doaj.org/article/4e3561bd67f740f69cdf357ffa89ab3f

Supplementary Materials and Methods from miR-155 Is Downregulated in Familial Adenomatous Polyposis and Modulates WNT Signaling by Targeting AXIN1 and TCF4

Autor: Luigi Ricciardiello, Franco Bazzoli, Claudio Montagna, Chiara Alquati, Daniela Turchetti, Sara Miccoli, Leonarda D'Angelo, Giulia Piazzi, Anna Prossomariti

APC gene target sequencing and in silico analysis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7f6bff73b50af8042127adb685cd56
https://doi.org/10.1158/1541-7786.22512121

Table S1 from miR-155 Is Downregulated in Familial Adenomatous Polyposis and Modulates WNT Signaling by Targeting AXIN1 and TCF4

Autor: Luigi Ricciardiello, Franco Bazzoli, Claudio Montagna, Chiara Alquati, Daniela Turchetti, Sara Miccoli, Leonarda D'Angelo, Giulia Piazzi, Anna Prossomariti

List of primary antibodies used for western blotting analysis.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d8d4ece653adbd2a09d12419e911fd
https://doi.org/10.1158/1541-7786.22512118.v1

Data from Highly Purified Eicosapentaenoic Acid as Free Fatty Acids Strongly Suppresses Polyps in ApcMin/+ Mice

Autor: Luigi Ricciardiello, C. Richard Boland, Robert M. Genta, Antonio Gasbarrini, Melissa Garcia, Michael Selgrad, Vincenzo Fogliano, Giulia Graziani, Alessandra Munarini, Andrea Belluzzi, Yahya Daoud, Claudio Ceccarelli, Giulia Piazzi, Lucia Fini

Purpose: Although cyclooxygenase (COX)-2 inhibitors could represent the most effective chemopreventive tool against colorectal cancer (CRC), their use in clinical practice is hampered by cardiovascular side effects. Consumption of ω-3-polyunsaturate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f691c573e4c1149db2e0ab91d29fc49
https://doi.org/10.1158/1078-0432.c.6518906.v1

Are Wnt/β-Catenin and PI3K/AKT/mTORC1 Distinct Pathways in Colorectal Cancer?Summary

Autor: Luigi Ricciardiello, Giulia Piazzi, Chiara Alquati, Anna Prossomariti

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 491-506 (2020)
Cellular and Molecular Gastroenterology and Hepatology

Wnt/β-catenin and phosphatidylinositol-3-kinase/protein kinase B/mammalian target of rapamycin complex 1 (PI3K/AKT/mTORC1) pathways both are critically involved in colorectal cancer (CRC) development, although they are implicated in the modulation o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7a306ac692719a8347e0c547725351
http://www.sciencedirect.com/science/article/pii/S2352345X20300515