Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Giulia Nizzoli"'
Autor:
Claudia Burrello, Federica Garavaglia, Fulvia Milena Cribiù, Giulia Ercoli, Gianluca Lopez, Jacopo Troisi, Angelo Colucci, Silvia Guglietta, Sara Carloni, Simone Guglielmetti, Valentina Taverniti, Giulia Nizzoli, Silvano Bosari, Flavio Caprioli, Maria Rescigno, Federica Facciotti
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Faecal microbiota transplantation (FMT) is becoming a therapeutic option in several gastrointestinal disorders. Here, Burrello et al. study the immunological mechanisms by which FMT reduces colonic inflammation and initiates the restoration of intest
Externí odkaz:
https://doaj.org/article/6f140d01828f4beeb27e25c2efa5c440
Autor:
Giulia Lovati, Maria Rescigno, Fulvia Milena Cribiù, Jens Geginat, Antonino Neri, Giulia Nizzoli, Katia Todoerti, Laura Porretti, Elena Trombetta, Claudia Burrello, Flavio Caprioli, Maurizio Vecchi, Fiorenzo Botti, Maria Rita Giuffrè, Federica Facciotti, Giulia Ercoli, Moira Paroni
Publikováno v:
Journal of Crohn's and Colitis. 12:981-992
Background and Aims: T helper 17 [Th17] cells are crucially involved in the immunopathogenesis of inflammatory bowel diseases in humans. Nevertheless, pharmacological blockade of interleukin 17A [IL17A], the Th17 signature cytokine, yielded negative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efed8bd8a8633d1ca2651f69f4242141
https://doi.org/10.1093/ecco-jcc/jjy051
https://doi.org/10.1093/ecco-jcc/jjy051
Autor:
Jens Geginat, Flavio Caprioli, Moira Paroni, Paola Larghi, Monica Moro, Raffaele De Francesco, Petra Neddermann, Massimiliano Pagani, Giulia Nizzoli, Sergio Abrignani, Maria Cristina Crosti
Publikováno v:
European Journal of Immunology. 46:1622-1632
IL-10 is an anti-inflammatory cytokine that inhibits maturation and cytokine production of dendritic cells (DCs). Although mature DCs have the unique capacity to prime CD8(+) CTL, IL-10 can promote CTL responses. To understand these paradoxic finding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fac93bffe9e44ea79369ccc148dcaed2
https://doi.org/10.1002/eji.201546136
https://doi.org/10.1002/eji.201546136
Autor:
Federica Facciotti, Sara Carloni, Flavio Caprioli, Gianluca Lopez, Maria Rescigno, Fulvia Milena Cribiù, Giulia Ercoli, Simone Guglielmetti, Federica Garavaglia, Silvano Bosari, Valentina Taverniti, Jacopo Troisi, Silvia Guglietta, Angelo Colucci, Giulia Nizzoli, Claudia Burrello
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications
Nature Communications
Alteration of the gut microbiota has been associated with different gastrointestinal disorders. Normobiosis restoration by faecal microbiota transplantation (FMT) is considered a promising therapeutic approach, even if the mechanisms underlying its e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d783dc63bdc93ffd3694a1348421a255
https://doi.org/10.1038/s41467-018-07359-8
https://doi.org/10.1038/s41467-018-07359-8
Autor:
Federica Facciotti, Petra Neddermann, Chiara Romagnani, Sergio Abrignani, Paola Gruarin, Svenja Steinfelder, Raffaele De Francesco, Anja Weick, Giulia Nizzoli, Annalisa Bianco, Lorenzo Pignataro, Carmen Scheibenbogen, Jens Geginat, Monica Moro, K Stölzel, Mariacristina Crosti, Bodo Steckel, Sara Torretta, Jana Krietsch
Publikováno v:
Blood. 122:932-942
Dendritic cells (DC) have the unique capacities to induce primary T-cell responses. In mice, CD8α(+)DC are specialized to cross-prime CD8(+) T cells and produce interleukin-12 (IL-12) that promotes cytotoxicity. Human BDCA-3(+)DC share several relev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b31acb0af9523695ca19f63d289fb37
https://doi.org/10.1182/blood-2013-04-495424
https://doi.org/10.1182/blood-2013-04-495424
Autor:
Pier Luigi Meroni, Richard A. Flavell, Moira Paroni, Sergio Abrignani, Giulia Nizzoli, Jens Geginat, A.E. Penatti, Nicola Gagliani, Paola Larghi, Massimiliano Pagani
Publikováno v:
Cytokinegrowth factor reviews. 30
Interleukin-10 (IL-10) is known to be a tolerogenic cytokine since it inhibits pro-inflammatory cytokine production and T cell stimulatory capacities of myeloid cells, such as macrophages and dendritic cells. In particular, it has a non-redundant tol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4e71e8c4fb78bd2cfc23e2e17411a88
https://pubmed.ncbi.nlm.nih.gov/26980675
https://pubmed.ncbi.nlm.nih.gov/26980675
Autor:
Giulia, Nizzoli, Paola, Larghi, Moira, Paroni, Maria Cristina, Crosti, Monica, Moro, Petra, Neddermann, Flavio, Caprioli, Massimiliano, Pagani, Raffaele, De Francesco, Sergio, Abrignani, Jens, Geginat
Publikováno v:
European journal of immunology. 46(7)
IL-10 is an anti-inflammatory cytokine that inhibits maturation and cytokine production of dendritic cells (DCs). Although mature DCs have the unique capacity to prime CD8(+) CTL, IL-10 can promote CTL responses. To understand these paradoxic finding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f31fbb4d3ce9319e6e43a0214a0a073d
https://pubmed.ncbi.nlm.nih.gov/27129615
https://pubmed.ncbi.nlm.nih.gov/27129615
Autor:
Bodo Steckel, Svenja Steinfelder, Stefano Maglie, Elisa Sugliano, Monica Moro, Flavio Caprioli, Fiorenzo Botti, Massimilliano Pagani, K Stölzel, Sergio Abrignani, Jens Geginat, Ilko Kastirr, Maria Cristina Crosti, Moira Paroni, Chiara Romagnani, Giulia Nizzoli, Johanna Sophie Alfen
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 193(7)
IL-21 promotes Th17 differentiation, and Th17 cells that upregulate T-bet, IFN-γ, and GM-CSF drive experimental autoimmune diseases in mice. Anti–IL-21 treatment of autoimmune patients is therefore a therapeutic option, but the role of IL-21 in hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d68a22d9853d776842c5e9d077fffa61
https://pubmed.ncbi.nlm.nih.gov/25172491
https://pubmed.ncbi.nlm.nih.gov/25172491
Autor:
Massimiliano Pagani, Sergio Abrignani, Luca Elli, Paola Larghi, Umberto Gianelli, Dario Conte, Jens Geginat, Flavio Caprioli, Silvia Tartari, Andrea Magarotto, Giulia Ercoli, Moira Paroni, Giulia Nizzoli
Publikováno v:
Clinical and Translational Gastroenterology
Objectives: To provide a functional and phenotypic characterization of immune cells infiltrating small intestinal mucosa during non-IPEX autoimmune enteropathy (AIE), as to gain insights on the pathogenesis of this clinical condition. Methods: Duoden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a97268f13b5240ee9f8a54c56ce459
https://doi.org/10.1038/ctg.2016.41
https://doi.org/10.1038/ctg.2016.41