Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Giulia Maurizi"'
Autor:
Chunxue Zhou, Henry H. Ruiz, Li Ling, Giulia Maurizi, Kenichi Sakamoto, Claudia G. Liberini, Ling Wang, Adrien Stanley, Hale E. Egritag, Sofia M. Sanz, Claudia Lindtner, Mary A. Butera, Christoph Buettner
Publikováno v:
Molecular Metabolism, Vol 78, Iss , Pp 101813- (2023)
Objective: Hepatic steatosis is a key initiating event in the pathogenesis of alcohol-associated liver disease (ALD), the most detrimental organ damage resulting from alcohol use disorder. However, the mechanisms by which alcohol induces steatosis re
Externí odkaz:
https://doaj.org/article/592fa73d8ff24ad284823221a6a6e218
Publikováno v:
Cell Transplantation, Vol 27 (2018)
Hematopoietic stem and progenitor cells reside within the bone marrow (BM) microenvironment. By a well-balanced interplay between self-renewal and differentiation, they ensure a lifelong supply of mature blood cells. Physiologically, multiple differe
Externí odkaz:
https://doaj.org/article/7b110737520b494f84cf1f4744c768fe
Autor:
Antonella Poloni, Giulia Maurizi, Lucia Babini, Federica Serrani, Eleonora Berardinelli, Stefania Mancini, Benedetta Costantini, Giancarlo Discepoli, Pietro Leoni
Publikováno v:
Cell Transplantation, Vol 20 (2011)
Mesenchymal stem cells (MSCs) are promising candidates for cell therapy and tissue engineering. Increasing evidence suggests that MSCs isolated from fetal tissues are more plastic and grow faster than adult MSCs. In this study, we characterized human
Externí odkaz:
https://doaj.org/article/96ab6d31d3f64d8093fa42d606d978f4
Autor:
Kenichi Sakamoto, Ling Li, Christoph Buettner, Giulia Maurizi, Chunxue Zhou, Claudia Liberini, Henry H. Ruiz
Publikováno v:
Journal of the Endocrine Society
Both obesity and aging increase susceptibility to metabolic disease and type 2 diabetes where adipose tissue dysfunction is a hallmark. In both conditions, impaired autonomic control is believed to play a key role in disrupted CNS control of metaboli
Publikováno v:
Journal of Cellular Physiology. 233:9077-9086
Adipose tissue is a dynamic endocrine organ playing a pivotal role in metabolism modulation. Adipocytes differentiation requires a highly orchestrated series of changes of gene expression in precursor cells. At the same time, white mature adipocytes
Publikováno v:
Journal of Cellular Physiology. 233:3784-3793
White mature adipocytes (MAs) are plastic cells able to reversibly transdifferentiate toward fibroblast‐like cells maintaining stem cell gene signatures. The main morphologic aspect of this transdifferentiation process, called liposecretion, is the
Publikováno v:
Stem Cells. 35:2340-2350
The transcription factor (TF) yes-associated protein 1 (YAP1) is a major effector of the tumor suppressive Hippo signaling pathway and is also necessary to maintain pluripotency in embryonic stem cells. Elevated levels of YAP1 expression antagonize t
Autor:
Pietro Leoni, Valerio Izzi, Domenico Mattiucci, Antonella Poloni, Giulia Maurizi, Marco Ciarlantini, Raffaele Pascarella, Marco Vivarelli, Attilio Olivieri, Emanuela Mensà, Stefania Mancini, Lorenzo Cenci
Publikováno v:
Journal of Cellular Physiology. 233:1500-1511
In bone marrow (BM), hematopoietic elements are mingled with adipocytes (BM-A), which are the most abundant stromal component in the niche. BM-A progressively increase with aging, eventually occupying up to 50% of BM cavities. In this work, the role
Autor:
Domenico Mattiucci, Saverio Cinti, Pietro Leoni, Marco Vivarelli, Antonio Giordano, Spartaco Santi, Jessica Perugini, Valerio Izzi, Angelica Giuliani, Maria Rita Rippo, Ilenia Severi, Massimo Falconi, Maria Cristina Zingaretti, Giulia Maurizi, Stefania Mancini, Angela Maurizi, Silvia Corvera, Antonella Poloni
Publikováno v:
Journal of Cellular Physiology. 232:2887-2899
White adipocytes are plastic cells able to reversibly transdifferentiate into brown adipocytes and into epithelial glandular cells under physiologic stimuli in vivo. These plastic properties could be used in future for regenerative medicine, but are
Autor:
Upal Basu-Roy, Kirk Rattanakorn, Preethi H. Gunaratne, Oran D. Kennedy, Giulia Maurizi, Michael J. Garabedian, Alka Mansukhani, Narendra Verma, Abhilash Gadi, Cristian Coarfa, Eugenia Han, Claudio Basilico
Publikováno v:
Oncotarget
Osteosarcoma (OS) is a highly aggressive pediatric bone cancer in which most tumor cells remain immature and fail to differentiate into bone-forming osteoblasts. However, OS cells readily respond to adipogenic stimuli suggesting they retain mesenchym