Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Giulia Mana"'
Autor:
Giulia Mana, Fabiana Clapero, Emiliano Panieri, Valentina Panero, Ralph T. Böttcher, Hui-Yuan Tseng, Federico Saltarin, Elena Astanina, Katarzyna I. Wolanska, Mark R. Morgan, Martin J. Humphries, Massimo M. Santoro, Guido Serini, Donatella Valdembri
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-20 (2016)
During vascular development, fibronectin (FN) is polymerized at the basolateral side of endothelial cells. Here Mana et al. propose a model where PPFIA1 drives recycling of the FN receptor, a5β1 integrin, to the cell surface and enables polar secret
Externí odkaz:
https://doaj.org/article/90e8d111851f4825bda14ec5af3b9486
Autor:
Camilla Ariano, Chiara Riganti, Davide Corà, Donatella Valdembri, Giulia Mana, Elena Astanina, Guido Serini, Federico Bussolino, Gabriella Doronzo
Publikováno v:
Angiogenesis. 25(4)
The dynamic integrin-mediated adhesion of endothelial cells (ECs) to the surrounding ECM is fundamental for angiogenesis both in physiological and pathological conditions, such as embryonic development and cancer progression. The dynamics of EC-to-EC
Autor:
Giulia Mana, Donatella Valdembri, Janet A Askari, Zhenhai Li, Patrick Caswell, Cheng Zhu, Martin J Humphries, Christoph Ballestrem, Guido Serini
Publikováno v:
Life Science Alliance. 6:e202201388
Modulation of integrin function is required in many physiological and pathological settings, such as angiogenesis and cancer. Integrin allosteric changes, clustering, and trafficking cooperate to regulate cell adhesion and motility on extracellular m
Autor:
Dora Tortarolo, Guido Serini, Chiara Sandri, Donatella Valdembri, Giulia Villari, Matteo Astone, Marco Arese, Chiara Camillo, Roxana E. Oberkersch, Dafne Gays, Noemi Gioelli, Fabiana Clapero, Giulia Mana, Massimo M. Santoro, Nicola Facchinello, Luca Tamagnone
Publikováno v:
bioRxiv
Dynamic modulation of endothelial cell-to-cell and cell-to-extracellular matrix (ECM) adhesion is essential for blood vessel patterning and functioning. Yet, the molecular mechanisms involved in this process have not been completely deciphered. We id
Publikováno v:
Biochemical Society Transactions
Spatiotemporal control of integrin-mediated cell adhesion to the extracellular matrix (ECM) is critical for physiological and pathological events in multicellular organisms, such as embryonic development, angiogenesis, platelet aggregation, leukocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d04e0604e3d868f3d86e47f96a6320d
http://hdl.handle.net/2318/1728559
http://hdl.handle.net/2318/1728559
Autor:
Valentina Panero, Mark R. Morgan, Katarzyna I. Wolanska, Guido Serini, Hui Yuan Tseng, Martin J. Humphries, Federico Saltarin, Ralph T. Böttcher, Giulia Mana, Emiliano Panieri, Donatella Valdembri, Elena Astanina, Massimo Santoro, Fabiana Clapero
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-20 (2016)
Mana, G, Clapero, F, Panieri, E, Panero, V, Böttcher, R T, Tseng, H-Y, Saltarin, F, Astanina, E, Wolanska, K I, Morgan, M R, Humphries, M J, Santoro, M M, Serini, G & Valdembri, D 2016, ' PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis ', Nature Communications, vol. 7, pp. 13546 . https://doi.org/10.1038/ncomms13546
Nature Communications, Vol 7, Iss 1, Pp 1-20 (2016)
Mana, G, Clapero, F, Panieri, E, Panero, V, Böttcher, R T, Tseng, H-Y, Saltarin, F, Astanina, E, Wolanska, K I, Morgan, M R, Humphries, M J, Santoro, M M, Serini, G & Valdembri, D 2016, ' PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis ', Nature Communications, vol. 7, pp. 13546 . https://doi.org/10.1038/ncomms13546
Basolateral polymerization of cellular fibronectin (FN) into a meshwork drives endothelial cell (EC) polarity and vascular remodelling. However, mechanisms coordinating α5β1 integrin-mediated extracellular FN endocytosis and exocytosis of newly syn