Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Giulia K. Buchmann"'
Autor:
Giulia K. Buchmann, Christoph Schürmann, Manuela Spaeth, Wesley Abplanalp, Lukas Tombor, David John, Timothy Warwick, Flávia Rezende, Andreas Weigert, Ajay M. Shah, Martin-Leo Hansmann, Norbert Weissmann, Stefanie Dimmeler, Katrin Schröder, Ralf P. Brandes
Publikováno v:
Redox Biology, Vol 45, Iss , Pp 102050- (2021)
Objective: The NADPH oxidase Nox4 is an important source of H2O2. Nox4-derived H2O2 limits vascular inflammation and promotes smooth muscle differentiation. On this basis, the role of Nox4 for restenosis development was determined in the mouse caroti
Externí odkaz:
https://doaj.org/article/1f3244d203f94483865ef6a1ec58116c
Autor:
Giulia K. Buchmann, Christoph Schürmann, Tim Warwick, Marcel H. Schulz, Manuela Spaeth, Oliver J. Müller, Katrin Schröder, Hanjoong Jo, Norbert Weissmann, Ralf P. Brandes
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101713- (2020)
Objective: Oxidative stress is a risk factor for atherosclerosis. NADPH oxidases of the Nox family produce ROS but their contribution to atherosclerosis development is less clear. Nox2 promotes and Nox4 rather limits atherosclerosis. Although Nox1 wi
Externí odkaz:
https://doaj.org/article/996afc4eb509477db95c66f5d64f8f17
Autor:
Julian U. G. Wagner, Lukas Tombor, Pedro Felipe Malacarne, Lisa-Maria Kettenhausen, Josefine Panthel, Maria Cipca, Kathrin A. Stilz, Ariane Fischer, Marion Muhly-Reinholz, Wesley T. Abplanalp, David John, Giulia K. Buchmann, Stephan Angendohr, Ehsan Amin, Katharina Scherschel, Nikolaj Klöcker, Malte Kelm, Dominik Schüttler, Sebastian Clauss, Stefan Guenther, Thomas Boettger, Thomas Braun, Christian Bär, Eleonora Nardini, Selma Osmanagic-Myers, Christian Meyer, Andreas M. Zeiher, Ralf P. Brandes, Guillermo Luxán, Stefanie Dimmeler
Aging is a major risk factor for impaired cardiovascular health. The aging myocardium is characterized by electrophysiological dysfunctions such as a reduced heart rate variability. These alterations can be intrinsic within cardiomyocytes, but might
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c37a05188cdbda288f09c07dba5011bf
https://doi.org/10.1101/2022.07.29.501999
https://doi.org/10.1101/2022.07.29.501999
Autor:
Giulia K Buchmann, Beatrice Pflüger-Müller, Manuela Spaeth, David John, Wesley T Abplanalp, Stefanie Dimmeler, Ralf P Brandes
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Background: The modulation of vascular smooth muscle cells (VSMC) phenotypes is a highly important process in the formation of neointima and in resolution of inflammation after vascular injury. Underlying genetic mechanisms that control the phenotypi
Autor:
Ralf P. Brandes, Andrea E. Vasconez, Stefan Offermanns, Katalin Pálfi, Eunjee Lee, Andreas Weigert, Jun Zhu, Christoph Schürmann, Praveen Mathoor, Matthias S. Leisegang, Christoph Kruse, Bart van de Sluis, James A. Oo, Shengpeng Wang, Giulia K. Buchmann, Franziska Luise Dienst, Patrick O. Humbert, Stefan Günther, Ilka Wittig
Publikováno v:
Cardiovascular Research, 115(14), 1963-1974. Oxford University Press
Aims The protein Scrib (Scribble 1) is known to control apico-basal polarity in epithelial cells. The role of polarity proteins in the vascular system remains poorly characterized; however, we previously reported that Scrib maintains the endothelial
Autor:
Norbert Weissmann, Andreas Weigert, Ralf P. Brandes, David John, Flávia Rezende, Timothy Warwick, Wesley Abplanalp, Ajay M. Shah, Stefanie Dimmeler, Martin-Leo Hansmann, Manuela Spaeth, Katrin Schröder, Giulia K. Buchmann, Christoph Schürmann, Lukas Tombor
Publikováno v:
Redox Biology, Vol 45, Iss, Pp 102050-(2021)
Redox Biology
Redox Biology
Objective The NADPH oxidase Nox4 is an important source of H2O2. Nox4-derived H2O2 limits vascular inflammation and promotes smooth muscle differentiation. On this basis, the role of Nox4 for restenosis development was determined in the mouse carotid
Autor:
Katrin Schröder, Norbert Weissmann, Christoph Schürmann, Tim Warwick, Giulia K. Buchmann, Manuela Spaeth, Oliver J. Müller, Ralf P. Brandes, Marcel H. Schulz, Hanjoong Jo
Publikováno v:
Redox Biology
Redox Biology, Vol 37, Iss, Pp 101713-(2020)
Redox Biology, Vol 37, Iss, Pp 101713-(2020)
Objective Oxidative stress is a risk factor for atherosclerosis. NADPH oxidases of the Nox family produce ROS but their contribution to atherosclerosis development is less clear. Nox2 promotes and Nox4 rather limits atherosclerosis. Although Nox1 wit
Autor:
Norbert Weissmann, Miklós Geiszt, Susan Scheibe, Mariola Bednorz, Christina A. Eichstaedt, Marija Gredic, Ekkehard Grünig, Simone Kraut, Niklas Müller, Hossein Ardeschir Ghofrani, Natascha Sommer, Nirmal Parajuli, Ralph T. Schermuly, Christine Veith, Werner Seeger, Friedrich Grimminger, Stefan Hadzic, Fenja Knoepp, Athanasios Fysikopoulos, Giulia K. Buchmann, Oleg Pak, Peter Dorfmüller, Flávia Rezende, Jochen Wilhelm, Peter Jaksch, Alexandra Pichl, Matthias Hecker, Katrin Schröder, Andreas Hecker, Srikanth Karnati, Winfried Padberg, Baktybek Kojonazarov, Cheng-Yu Wu, Stefan Gattenlöhner, Zeki I. Kanbagli, Ralf P. Brandes, Andreas Günther, Eveline Baumgart-Vogt, Ingrid Henneke, Claus Vogelmeier, Ilka Wittig, Walter Klepetko, Michael Seimetz, Katrin Hinderhofer
Publikováno v:
Nature metabolism. 2(6)
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and death worldwide. Peroxynitrite, formed from nitric oxide, which is derived from inducible nitric oxide synthase, and superoxide, has been implicated in the development of
Autor:
Ralf P. Brandes, Giulia K. Buchmann, Christoph Schürmann, Iris Bischoff, Elke H. Heiss, Jeremy Epah, Robert Fürst, Simone Fuchs, Jacqueline Bräutigam
Publikováno v:
Journal of molecular and cellular cardiology. 135
The process of angiogenesis is involved in several pathological conditions, such as tumor growth or age-related macular degeneration. Although the available anti-angiogenic drugs have improved the therapy of these diseases, major drawbacks, such as u
Autor:
Friedrich Grimminger, Katrin Schröder, Baktybek Kojonazarov, Ralph T. Schermuly, Cheng-Yu Wu, Mariola Bednorz, Simone Kraut, Athanasios Fysikopoulos, Giulia K. Buchmann, Nirmal Parajuli, Ilka Wittig, Jochen Wilhelm, Peter Jaksch, Werner Seeger, Stefan Gattenlöhner, Niklas Müller, Eveline Baumgart-Vogt, Winfried Padberg, Christina A. Eichstaedt, Srikanth Karnati, Ralf P. Brandes, Christine Veith, Fenja Knoepp, Norbert Weissmann, Peter Dorfmüller, Stefan Hadzic, Miklós Geiszt, Susan Scheibe, Flávia Rezende, Natascha Sommer, Alexandra Pichl, Zeki I. Kanbagli, Andreas Hecker, Hossein Ardeschir Ghofrani, Andreas Günther, Ingrid Henneke, Claus Vogelmeier, Michael Seimetz, Katrin Hinderhofer, Walter Klepetko, Matthias Hecker, Marija Gredic, Ekkehard Grünig, Oleg Pak
Publikováno v:
Nature Metabolism. 2:648-648