Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Giulia Di Lazzaro"'
Autor:
Giulia Di Lazzaro, Anna Picca, Sofia Boldrini, Francesco Bove, Emanuele Marzetti, Martina Petracca, Carla Piano, Anna Rita Bentivoglio, Paolo Calabresi
Publikováno v:
Neurobiology of Disease, Vol 190, Iss , Pp 106371- (2024)
Objective: Neurodegeneration and neuroinflammation are two intertwined mechanisms contributing to the pathophysiology of Parkinson's disease. Whether circulating biomarkers reflecting those two processes differ according to disease duration remains t
Externí odkaz:
https://doaj.org/article/49950b7dd6784b588f7c1659d6f92748
Autor:
Paolo Calabresi, Alessandro Mechelli, Giuseppina Natale, Laura Volpicelli-Daley, Giulia Di Lazzaro, Veronica Ghiglieri
Publikováno v:
Cell Death and Disease, Vol 14, Iss 3, Pp 1-16 (2023)
Abstract Although the discovery of the critical role of α-synuclein (α-syn) in the pathogenesis of Parkinson’s disease (PD) is now twenty-five years old, it still represents a milestone in PD research. Abnormal forms of α-syn trigger selective a
Externí odkaz:
https://doaj.org/article/4a799612ef0a454eb77b20620a3ac9e8
Autor:
Giulia Di Lazzaro, Mariachiara Ricci, Giovanni Saggio, Giovanni Costantini, Tommaso Schirinzi, Mohammad Alwardat, Luca Pietrosanti, Martina Patera, Simona Scalise, Franco Giannini, Antonio Pisani
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-7 (2021)
Abstract Early noninvasive reliable biomarkers are among the major unmet needs in Parkinson’s disease (PD) to monitor therapy response and disease progression. Objective measures of motor performances could allow phenotyping of subtle, undetectable
Externí odkaz:
https://doaj.org/article/36fff3116f8a4b8fbf7c31657fbfb239
Autor:
Antonio Suppa, Giovanni Costantini, Francesco Asci, Pietro Di Leo, Mohammad Sami Al-Wardat, Giulia Di Lazzaro, Simona Scalise, Antonio Pisani, Giovanni Saggio
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
IntroductionParkinson's disease (PD) is characterized by specific voice disorders collectively termed hypokinetic dysarthria. We here investigated voice changes by using machine learning algorithms, in a large cohort of patients with PD in different
Externí odkaz:
https://doaj.org/article/1975b249da82416cb47484df4f3eb844
Autor:
Paraskevi Krashia, Alberto Cordella, Annalisa Nobili, Livia La Barbera, Mauro Federici, Alessandro Leuti, Federica Campanelli, Giuseppina Natale, Gioia Marino, Valeria Calabrese, Francescangelo Vedele, Veronica Ghiglieri, Barbara Picconi, Giulia Di Lazzaro, Tommaso Schirinzi, Giulia Sancesario, Nicolas Casadei, Olaf Riess, Sergio Bernardini, Antonio Pisani, Paolo Calabresi, Maria Teresa Viscomi, Charles Nicholas Serhan, Valerio Chiurchiù, Marcello D’Amelio, Nicola Biagio Mercuri
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Resolvins are endogenous lipids with pro-resolving activity. Here the authors find that rats overexpressing human α-synuclein show defects in dopamine signalling before dopamine cell loss, and that this is associated with low Resolvin D1 levels and
Externí odkaz:
https://doaj.org/article/4400ee42af354c6ca10e2b68760be226
Dietary Vitamin E as a Protective Factor for Parkinson's Disease: Clinical and Experimental Evidence
Autor:
Tommaso Schirinzi, Giuseppina Martella, Paola Imbriani, Giulia Di Lazzaro, Donatella Franco, Vito Luigi Colona, Mohammad Alwardat, Paola Sinibaldi Salimei, Nicola Biagio Mercuri, Mariangela Pierantozzi, Antonio Pisani
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Effective disease-modifying treatments are an urgent need for Parkinson's disease (PD). A putative successful strategy is to counteract oxidative stress, not only with synthetic compounds, but also with natural agents or dietary choices. Vitamin E, i
Externí odkaz:
https://doaj.org/article/88fbd392e028453f92e8dd4e2731061a
Autor:
Giulia Di Lazzaro, Tommaso Schirinzi, Maria Pia Giambrone, Roberta Di Mauro, Maria Giuseppina Palmieri, Camilla Rocchi, Michele Tinazzi, Nicola Biagio Mercuri, Stefano Di Girolamo, Antonio Pisani
Publikováno v:
Parkinson's Disease, Vol 2018 (2018)
Introduction. Pisa syndrome (PS) is a postural complication of Parkinson’s disease (PD). Yet, its pathophysiology remains unclear, although a multifactorial component is probable. Cervical vestibular evoked myogenic potentials (cVEMPs) explore vest
Externí odkaz:
https://doaj.org/article/6bb96afc7b6642b3b9a3e8c4c9776f3b
Autor:
Paraskevi Krashia, Alberto Cordella, Annalisa Nobili, Livia La Barbera, Mauro Federici, Alessandro Leuti, Federica Campanelli, Giuseppina Natale, Gioia Marino, Valeria Calabrese, Francescangelo Vedele, Veronica Ghiglieri, Barbara Picconi, Giulia Di Lazzaro, Tommaso Schirinzi, Giulia Sancesario, Nicolas Casadei, Olaf Riess, Sergio Bernardini, Antonio Pisani, Paolo Calabresi, Maria Teresa Viscomi, Charles Nicholas Serhan, Valerio Chiurchiù, Marcello D’Amelio, Nicola Biagio Mercuri
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/39d735d5afbb4a90ae8859de29c2c544
Autor:
Tommaso Schirinzi, Giuseppina Martella, Alessio D’Elia, Giulia Di Lazzaro, Paola Imbriani, Graziella Madeo, Leonardo Monaco, Marta Maltese, Antonio Pisani
Publikováno v:
Parkinson's Disease, Vol 2016 (2016)
The multifactorial pathogenesis of Parkinson’s Disease (PD) requires a careful identification of populations “at risk” of developing the disease. In this case-control study we analyzed a large Italian population, in an attempt to outline genera
Externí odkaz:
https://doaj.org/article/d65d28dd9b0f494f9ad57fb93eeb92a4
Autor:
Mariachiara Ricci, Giulia Di Lazzaro, Vito Errico, Antonio Pisani, Franco Giannini, Giovanni Saggio
Publikováno v:
IEEE Journal of Biomedical and Health Informatics. 26:2920-2928
In order to evaluate Parkinson disease patients' response to therapeutic interventions, sources of information are mainly patient reports and clinicians' assessment of motor functions. However, these sources can suffer from patient's subjectivity and