Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Giulia Di Lazzaro"'
Autor:
Giulia Di Lazzaro, Anna Picca, Sofia Boldrini, Francesco Bove, Emanuele Marzetti, Martina Petracca, Carla Piano, Anna Rita Bentivoglio, Paolo Calabresi
Publikováno v:
Neurobiology of Disease, Vol 190, Iss , Pp 106371- (2024)
Objective: Neurodegeneration and neuroinflammation are two intertwined mechanisms contributing to the pathophysiology of Parkinson's disease. Whether circulating biomarkers reflecting those two processes differ according to disease duration remains t
Externí odkaz:
https://doaj.org/article/49950b7dd6784b588f7c1659d6f92748
Autor:
Paolo Calabresi, Alessandro Mechelli, Giuseppina Natale, Laura Volpicelli-Daley, Giulia Di Lazzaro, Veronica Ghiglieri
Publikováno v:
Cell Death and Disease, Vol 14, Iss 3, Pp 1-16 (2023)
Abstract Although the discovery of the critical role of α-synuclein (α-syn) in the pathogenesis of Parkinson’s disease (PD) is now twenty-five years old, it still represents a milestone in PD research. Abnormal forms of α-syn trigger selective a
Externí odkaz:
https://doaj.org/article/4a799612ef0a454eb77b20620a3ac9e8
Autor:
Giulia Di Lazzaro, Mariachiara Ricci, Giovanni Saggio, Giovanni Costantini, Tommaso Schirinzi, Mohammad Alwardat, Luca Pietrosanti, Martina Patera, Simona Scalise, Franco Giannini, Antonio Pisani
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-7 (2021)
Abstract Early noninvasive reliable biomarkers are among the major unmet needs in Parkinson’s disease (PD) to monitor therapy response and disease progression. Objective measures of motor performances could allow phenotyping of subtle, undetectable
Externí odkaz:
https://doaj.org/article/36fff3116f8a4b8fbf7c31657fbfb239
Autor:
Antonio Suppa, Giovanni Costantini, Francesco Asci, Pietro Di Leo, Mohammad Sami Al-Wardat, Giulia Di Lazzaro, Simona Scalise, Antonio Pisani, Giovanni Saggio
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
IntroductionParkinson's disease (PD) is characterized by specific voice disorders collectively termed hypokinetic dysarthria. We here investigated voice changes by using machine learning algorithms, in a large cohort of patients with PD in different
Externí odkaz:
https://doaj.org/article/1975b249da82416cb47484df4f3eb844
Autor:
Paraskevi Krashia, Alberto Cordella, Annalisa Nobili, Livia La Barbera, Mauro Federici, Alessandro Leuti, Federica Campanelli, Giuseppina Natale, Gioia Marino, Valeria Calabrese, Francescangelo Vedele, Veronica Ghiglieri, Barbara Picconi, Giulia Di Lazzaro, Tommaso Schirinzi, Giulia Sancesario, Nicolas Casadei, Olaf Riess, Sergio Bernardini, Antonio Pisani, Paolo Calabresi, Maria Teresa Viscomi, Charles Nicholas Serhan, Valerio Chiurchiù, Marcello D’Amelio, Nicola Biagio Mercuri
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Resolvins are endogenous lipids with pro-resolving activity. Here the authors find that rats overexpressing human α-synuclein show defects in dopamine signalling before dopamine cell loss, and that this is associated with low Resolvin D1 levels and
Externí odkaz:
https://doaj.org/article/4400ee42af354c6ca10e2b68760be226
Autor:
Mariachiara Ricci, Giulia Di Lazzaro, Vito Errico, Antonio Pisani, Franco Giannini, Giovanni Saggio
Publikováno v:
IEEE Journal of Biomedical and Health Informatics. 26:2920-2928
In order to evaluate Parkinson disease patients' response to therapeutic interventions, sources of information are mainly patient reports and clinicians' assessment of motor functions. However, these sources can suffer from patient's subjectivity and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93ec401e20b4f50ea5895fd89f91410
https://doi.org/10.1109/jbhi.2022.3160103
https://doi.org/10.1109/jbhi.2022.3160103
Dietary Vitamin E as a Protective Factor for Parkinson's Disease: Clinical and Experimental Evidence
Autor:
Tommaso Schirinzi, Giuseppina Martella, Paola Imbriani, Giulia Di Lazzaro, Donatella Franco, Vito Luigi Colona, Mohammad Alwardat, Paola Sinibaldi Salimei, Nicola Biagio Mercuri, Mariangela Pierantozzi, Antonio Pisani
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Effective disease-modifying treatments are an urgent need for Parkinson's disease (PD). A putative successful strategy is to counteract oxidative stress, not only with synthetic compounds, but also with natural agents or dietary choices. Vitamin E, i
Externí odkaz:
https://doaj.org/article/88fbd392e028453f92e8dd4e2731061a
Autor:
Maria Caterina Silveri, Sonia Di Tella, Maria Rita Lo Monaco, Martina Petracca, Alice Tondinelli, Gabriella Antonucci, Gino Pozzi, Giulia Di Lazzaro, Paolo Calabresi, Anna Rita Bentivoglio
Publikováno v:
Acta Neurologica Scandinavica. 145:571-578
Functional movement disorders (FMD) refer to a heterogeneous group of manifestations incongruent with known neurological diseases. Functional neuroimaging studies in FMD indicate the overlap between cerebral regions in which abnormal activation occur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f315ba4aaab84d253c284f743d44a3ec
https://doi.org/10.1111/ane.13585
https://doi.org/10.1111/ane.13585
The critical role of alpha-synuclein in Parkinson’s disease represents a pivotal discovery. Some progress has been made in recent years in identifying disease-modifying therapies for Parkinson’s disease that target alpha-synuclein. However, these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1615a87fefdfc66a5a3b5c6d886f6f03
https://hdl.handle.net/10807/235239
https://hdl.handle.net/10807/235239
Autor:
Marco Perulli, Josephine Poole, Giulia Di Lazzaro, Sasha D'Ambrosio, Katri Silvennoinen, Sara Zagaglia, Diego Jiménez‐Jiménez, Domenica Battaglia, Sanjay M. Sisodiya, Simona Balestrini
Publikováno v:
Movement Disorders Clinical Practice. 9:206-211
Although described as non-progressive, alternating hemiplegia of childhood (AHC) can display a sudden deterioration, anecdotally reported mainly in childhood. Outcome in adulthood is uncertain.Aim of this study is to describe the long-term follow-up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab21b4c031b67d2e98707935d3d2769
https://doi.org/10.1002/mdc3.13388
https://doi.org/10.1002/mdc3.13388