Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Giulia Chiavegato"'
Autor:
Valerio Marino, Giovanni Gotte, Maria Chiara Monti, Flora Cozzolino, Sofia Mariotto, Piero Pucci, Elena Butturini, Diana Canetti, Giulia Chiavegato, Daniele Dell'Orco
Signal transducer and activator of transcription 3 (STAT3) is a transcription factor activated by the phosphorylation of tyrosine 705 in response to many cytokines and growth factors. Recently, the roles for unphosphorylated STAT3 (U-STAT3) have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad22d0b18c0bfdf814f6b12bc716becc
http://hdl.handle.net/11588/646396
http://hdl.handle.net/11588/646396
Autor:
Sofia Mariotto, Elena Darra, Maria Chiara Monti, Barbara Cellini, Piero Pucci, Flora Cozzolino, Elena Butturini, Giulia Chiavegato, Daniele Dell'Orco
Publikováno v:
ACS chemical biology. 9(8)
STAT3 is a latent transcription factor that promotes cell survival and proliferation and is often constitutively active in cancers. Although many reports provide evidence that STAT3 is a direct target of oxidative stress, its redox regulation is poor
Autor:
Alessandra Carcereri de Prati, Giulia Chiavegato, Antonella Rigo, Elena Darra, Elena Butturini, Elisabetta Cavalieri, Sofia Mariotto
Publikováno v:
Free radical biologymedicine. 65
STAT3 is a transcription factor constitutively activated in a variety of cancers that has a critical role in the inhibition of apoptosis and induction of chemoresistance. Inhibition of the STAT3 signaling pathway suppresses cell survival signals and