Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Giulia Cazzaniga"'
Publikováno v:
Molbank, Vol 2024, Iss 2, p M1806 (2024)
In the context of our ongoing studies on chromane derivatives as inhibitors of the salicylate synthase from M. tuberculosis, we isolated a new, unexpected compound from the cyclization of 3-(propargyloxy)-5-benzyloxy-benzoic acid methyl ester. Its mo
Externí odkaz:
https://doaj.org/article/165072210f2f470db8aa40ba46e76957
Autor:
Matteo Mori, Andrea Tresoldi, Stefania Villa, Giulia Cazzaniga, Marco Bellinzoni, Fiorella Meneghetti
Publikováno v:
Molbank, Vol 2022, Iss 4, p M1515 (2022)
The ever-evolving research in the field of antitubercular agents has led to the identification of several new potential drug classes. Among them, 5-phenyl-furan-2-carboxylic acids have emerged as innovative potential therapeutics, targeting iron acqu
Externí odkaz:
https://doaj.org/article/a60338ad01c04f398bc98694de55ccdd
Publikováno v:
Molbank, Vol 2022, Iss 4, p M1492 (2022)
5-Phenyl-furan-2-carboxylic acids have emerged as a new, promising class of antimycobacterial agents that have the ability to interfere with iron homeostasis. Considering the lack of structural data on these compounds, we analyzed the crystal of a fl
Externí odkaz:
https://doaj.org/article/9fd9d8b91ad8404e9220085e1b48031c
Autor:
Davide Capelli, Giulia Cazzaniga, Matteo Mori, Antonio Laghezza, Fulvio Loiodice, Martina Quaglia, Elisa Negro, Fiorella Meneghetti, Stefania Villa, Roberta Montanari
Publikováno v:
Biomolecules, Vol 13, Iss 4, p 694 (2023)
PPARγ represents a key target for the treatment of type 2 diabetes and metabolic syndrome. To avoid serious adverse effects related to the PPARγ agonism profile of traditional antidiabetic drugs, a new opportunity is represented by the development
Externí odkaz:
https://doaj.org/article/48a2d402920e430a9dc364be84f2f22f
Autor:
Matteo Mori, Giovanni Stelitano, Giulia Cazzaniga, Arianna Gelain, Andrea Tresoldi, Mario Cocorullo, Martina Roversi, Laurent R. Chiarelli, Martina Tomaiuolo, Pietro Delre, Giuseppe F. Mangiatordi, Anna Griego, Loris Rizzello, Alberto Cassetta, Sonia Covaceuszach, Stefania Villa, Fiorella Meneghetti
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 502 (2023)
Targeting pathogenic mechanisms, rather than essential processes, represents a very attractive approach for the development of new antimycobacterial drugs. In this context, iron acquisition routes have recently emerged as potentially druggable pathwa
Externí odkaz:
https://doaj.org/article/0e262c2fdf194bf3a2bdc22d88bd3f07
Autor:
Matteo Mori, Giovanni Stelitano, Anna Griego, Laurent R. Chiarelli, Giulia Cazzaniga, Arianna Gelain, Elena Pini, Marina Camera, Paola Canzano, Andrea Fumagalli, Edoardo Scarpa, Chiara Cordiglieri, Loris Rizzello, Stefania Villa, Fiorella Meneghetti
Publikováno v:
Pharmaceuticals, Vol 15, Iss 8, p 992 (2022)
Tuberculosis (TB) causes millions of deaths every year, ranking as one of the most dangerous infectious diseases worldwide. Because several pathogenic strains of M. tuberculosis (Mtb) have developed resistance against most of the established anti-TB
Externí odkaz:
https://doaj.org/article/a89679d5dd8a4796a26f8260240379b5
Publikováno v:
Molecules, Vol 27, Iss 14, p 4449 (2022)
SIRT5 is a member of the Sirtuin family, a class of deacetylating enzymes consisting of seven isoforms, involved in the regulation of several processes, including gene expression, metabolism, stress response, and aging. Considering that the anomalous
Externí odkaz:
https://doaj.org/article/cd1b12591eb1475fae314c01aff258f2
Autor:
Matteo Mori, Fiorella Meneghetti, Laurent R. Chiarelli, Alessia Diego, Donatella Nava, Arianna Gelain, Giulia Cazzaniga, Stefania Villa, Elena Pini
Publikováno v:
Molbank, Vol 2020, Iss 2, p M1143 (2020)
6-Hydroxy-2-methylbenzofuran-4-carboxylic acid was synthesized in two steps, starting from 3,5-dihydroxybenzoate. The product was obtained through a direct thermal one-pot cyclization with propargyl bromide, followed by a base-catalyzed hydrolysis. I
Externí odkaz:
https://doaj.org/article/3964dd44d37c4695a270d3f73bae04a3
Autor:
Sandra Oloketuyi, Robert Bernedo, Andreas Christmann, Justyna Borkowska, Giulia Cazzaniga, Horst Wilhelm Schuchmann, Joanna Niedziółka-Jönsson, Katarzyna Szot-Karpińska, Harald Kolmar, Ario de Marco
Publikováno v:
Biosensors, Vol 11, Iss 12, p 496 (2021)
C-reactive protein (CRP) is an inflammation biomarker that should be quantified accurately during infections and healing processes. Nanobodies are good candidates to replace conventional antibodies in immunodiagnostics due to their inexpensive produc
Externí odkaz:
https://doaj.org/article/a0d0d89b5196432ebcfb8f266fa9f8c9
Autor:
Matteo Mori, Giovanni Stelitano, Laurent R. Chiarelli, Giulia Cazzaniga, Arianna Gelain, Daniela Barlocco, Elena Pini, Fiorella Meneghetti, Stefania Villa
Publikováno v:
Pharmaceuticals, Vol 14, Iss 2, p 155 (2021)
Tuberculosis (TB) causes millions of deaths every year, ranking as one of the most dangerous infectious diseases worldwide. Because several pathogenic strains of Mycobacterium tuberculosis (Mtb) have developed resistance against most of the establish
Externí odkaz:
https://doaj.org/article/9b85a7096bf347e7aa5d0a78f21d473e