Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Giulia Calabretto"'
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
T cell large granular lymphocyte clones that persist over time and that exhibit molecular and immunophenotypic features closely resembling those of T-cell Large Granular Lymphocyte Leukemia (T-LGLL) may be detectable in individuals who lack any clini
Externí odkaz:
https://doaj.org/article/8fca45ea253244ebb9c1a92363ecb476
Autor:
Gianpietro Semenzato, Giulia Calabretto, Antonella Teramo, Vanessa Rebecca Gasparini, Elisa Rampazzo, Gregorio Barilà, Renato Zambello
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Type T Large Granular Lymphocyte Leukemia (T-LGLL) is a chronic disorder characterized by the abnormal proliferation of clonal cytotoxic T cells. The intriguing association of T-LGLL with autoimmune and inflammatory diseases, the most promin
Externí odkaz:
https://doaj.org/article/225c8291ea9f482da0689d91ab69e60c
Autor:
Cristina Vicenzetto, Vanessa Rebecca Gasparini, Gregorio Barila, Antonella Teramo, Giulia Calabretto, Elisa Rampazzo, Samuela Carraro, Valentina Trimarco, Livio Trentin, Monica Facco, Gianpietro Semenzato, Renato Zambello
Publikováno v:
Haematologica, Vol 109, Iss 1 (2023)
T-cell large granular lymphocyte leukemia (T-LGLL) is a chronic lymphoproliferative disorder characterized by the clonal expansion of T-cell large granular lymphocytes (T-LGL). Immunophenotypic and genotypic features contribute to discriminate sympto
Externí odkaz:
https://doaj.org/article/7289ccc402464f298a85142aa37646a9
Autor:
Antonella Teramo, Andrea Binatti, Elena Ciabatti, Gianluca Schiavoni, Giulia Tarrini, Gregorio Barilà, Giulia Calabretto, Cristina Vicenzetto, Vanessa Rebecca Gasparini, Monica Facco, Iacopo Petrini, Roberto Grossi, Nadia Pisanti, Stefania Bortoluzzi, Brunangelo Falini, Enrico Tiacci, Sara Galimberti, Gianpietro Semenzato, Renato Zambello
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Tγδ large granular lymphocyte leukemia (Tγδ LGLL) is a rare lymphoproliferative neoplasm characterized by the expansion of T large granular lymphocytes expressing γδ TCR. Here, based on deep sequencing analysis of the clonotype repertoire, the
Externí odkaz:
https://doaj.org/article/3eccd5369eaa41acac78c80e57f997f1
Autor:
Dipabarna Bhattacharya, Antonella Teramo, Vanessa Rebecca Gasparini, Jani Huuhtanen, Daehong Kim, Jason Theodoropoulos, Gianluca Schiavoni, Gregorio Barilà, Cristina Vicenzetto, Giulia Calabretto, Monica Facco, Toru Kawakami, Hideyuki Nakazawa, Brunangelo Falini, Enrico Tiacci, Fumihiro Ishida, Gianpietro Semenzato, Tiina Kelkka, Renato Zambello, Satu Mustjoki
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 2, Pp 1-12 (2022)
Abstract CD4+ T-cell large granular lymphocyte leukemia (T-LGLL) is a rare subtype of T-LGLL with unknown etiology. In this study, we molecularly characterized a cohort of patients (n = 35) by studying their T-cell receptor (TCR) repertoire and the p
Externí odkaz:
https://doaj.org/article/301d196f876344169d0f3ab949749ead
Autor:
Gregorio Barilà, Laura Pavan, Susanna Vedovato, Tamara Berno, Mariella Lo Schirico, Massimiliano Arangio Febbo, Antonella Teramo, Giulia Calabretto, Cristina Vicenzetto, Vanessa Rebecca Gasparini, Anna Fregnani, Sabrina Manni, Valentina Trimarco, Samuela Carraro, Monica Facco, Francesco Piazza, Gianpietro Semenzato, Renato Zambello
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The biology of plasma cell dyscrasias (PCD) involves both genetic and immune-related factors. Since genetic lesions are necessary but not sufficient for Multiple Myeloma (MM) evolution, several authors hypothesized that immune dysfunction involving b
Externí odkaz:
https://doaj.org/article/aa392056c4d24cceb4f1fb0de96bdb62
Autor:
Edoardo Giussani, Andrea Binatti, Giulia Calabretto, Vanessa Rebecca Gasparini, Antonella Teramo, Cristina Vicenzetto, Gregorio Barilà, Monica Facco, Alessandro Coppe, Gianpietro Semenzato, Stefania Bortoluzzi, Renato Zambello
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Large granular lymphocyte leukemias (LGLL) are sustained by proliferating cytotoxic T cells or NK cells, as happens in Chronic Lymphoproliferative Disorder of Natural Killer cells (CLPD-NK), whose etiology is only partly understood. Different hypothe
Externí odkaz:
https://doaj.org/article/67c347e9abce45a6bcff9a49703809b9
Autor:
Barbara Mariotti, Giulia Calabretto, Marzia Rossato, Antonella Teramo, Monica Castellucci, Gregorio Barilà, Matteo Leoncin, Cristina Vicenzetto, Monica Facco, Gianpietro Semenzato, Flavia Bazzoni, Renato Zambello
Publikováno v:
Haematologica, Vol 105, Iss 5 (2020)
Tlarge granular lymphocyte leukemia (T-LGLL) is characterized by the expansion of several large granular lymphocyte clones, among which a subset of large granular lymphocytes showing constitutively activated STAT3, a specific CD8+/CD4− phenotype an
Externí odkaz:
https://doaj.org/article/23935d066a57450891eada6c1e5d0c68
Autor:
Antonella Teramo, Gregorio Barilà, Giulia Calabretto, Cristina Vicenzetto, Vanessa Rebecca Gasparini, Gianpietro Semenzato, Renato Zambello
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Large granular lymphocyte leukemia (LGLL) is a chronic proliferation of clonal cytotoxic lymphocytes, usually presenting with cytopenias and yet lacking a specific therapy. The disease is heterogeneous, including different subsets of patients disting
Externí odkaz:
https://doaj.org/article/6f41fb88406b46c2a8486bf9608659db
Autor:
Giulia Calabretto, Antonella Teramo, Gregorio Barilà, Cristina Vicenzetto, Vanessa Rebecca Gasparini, Gianpietro Semenzato, Renato Zambello
Publikováno v:
Cells, Vol 10, Iss 10, p 2800 (2021)
Large granular lymphocyte leukemia (LGLL) is a rare lymphoproliferative disorder characterized by the clonal expansion of cytotoxic T-LGL or NK cells. Chronic isolated neutropenia represents the clinical hallmark of the disease, being present in up t
Externí odkaz:
https://doaj.org/article/79c5e70521694fcb8ba8a72d4326f0c1