Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Giulia C, Kennedy"'
Autor:
Diana H. Yu, Majid Shafiq, Hitesh Batra, Marla Johnson, Bailey Griscom, Janna Chamberlin, Lori R. Lofaro, Jing Huang, William A. Bulman, Giulia C. Kennedy, Lonny B. Yarmus, Hans J. Lee, David Feller-Kopman
Publikováno v:
BMC Pulmonary Medicine, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Bronchoscopy is commonly utilized for non-surgical sampling of indeterminant pulmonary lesions, but nondiagnostic procedures are common. Accurate assessment of the risk of malignancy is essential for decision making in these patie
Externí odkaz:
https://doaj.org/article/afac93aa4f45404b844cf71204491f34
Autor:
Sonali Sethi, Scott Oh, Alexander Chen, Christina Bellinger, Lori Lofaro, Marla Johnson, Jing Huang, Sangeeta Maruti Bhorade, William Bulman, Giulia C. Kennedy
Publikováno v:
BMC Pulmonary Medicine, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Incidental and screening-identified lung nodules are common, and a bronchoscopic evaluation is frequently nondiagnostic. The Percepta Genomic Sequencing Classifier (GSC) is a genomic classifier developed in current and former smok
Externí odkaz:
https://doaj.org/article/5d3ffcd3ee4543aeb6c8e66d9e6fa40c
Autor:
Dorota Whitmer, John E. Phay, Shelby Holt, Benjamin O’Donnell, Jay Nguyen, Dennis Joseph, Anthony Chi, Shuyang Wu, Yangyang Hao, Jing Huang, Joshua P. Klopper, Richard T. Kloos, Giulia C. Kennedy, Joyce Shin
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
ObjectivesTo evaluate the frequency and risk of malignancy of TSHRpI568T mutations discovered in indeterminate thyroid nodules (ITN) within the Veracyte CLIA laboratory undergoing Afirma® Genomic Sequencing Classifier (GSC) testing, and to evaluate
Externí odkaz:
https://doaj.org/article/b4fd7c23e2e14b2ea15fab429cacb8d9
Autor:
Marla K. Johnson, Shuyang Wu, Daniel G. Pankratz, Grazyna Fedorowicz, Jessica Anderson, Jie Ding, Mei Wong, Manqiu Cao, Joshua Babiarz, Lori Lofaro, P. Sean Walsh, Giulia C. Kennedy, Jing Huang
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Bronchoscopy is a common procedure used for evaluation of suspicious lung nodules, but the low diagnostic sensitivity of bronchoscopy often results in inconclusive results and delays in treatment. Percepta Genomic Sequencing Class
Externí odkaz:
https://doaj.org/article/3de86b5178924c0d9866c1fbec4c09c8
Autor:
Yoonha Choi, Jianghan Qu, Shuyang Wu, Yangyang Hao, Jiarui Zhang, Jianchang Ning, Xinwu Yang, Lori Lofaro, Daniel G. Pankratz, Joshua Babiarz, P. Sean Walsh, Ehab Billatos, Marc E. Lenburg, Giulia C. Kennedy, Jon McAuliffe, Jing Huang
Publikováno v:
BMC Medical Genomics, Vol 13, Iss S10, Pp 1-15 (2020)
Abstract Background Bronchoscopy for suspected lung cancer has low diagnostic sensitivity, rendering many inconclusive results. The Bronchial Genomic Classifier (BGC) was developed to help with patient management by identifying those with low risk of
Externí odkaz:
https://doaj.org/article/71b03ddf3d3c44e8ab579b3abb4de98e
Autor:
Peter Mazzone, Travis Dotson, Momen M Wahidi, Michael Bernstein, Hans J Lee, David Feller Kopman, Lonny Yarmus, Duncan Whitney, Christopher Stevenson, Jianghan Qu, Marla Johnson, P Sean Walsh, Jing Huang, Lori R Lofaro, Sangeeta M Bhorade, Giulia C Kennedy, Avrum Spira, M Patricia Rivera, AEGIS Study Team, Percepta Registry Investigators
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0268567 (2022)
The Percepta Genomic Sequencing Classifier (GSC) was developed to up-classify as well as down-classify the risk of malignancy for lung lesions when bronchoscopy is non-diagnostic. We evaluated the performance of Percepta GSC in risk re-classification
Externí odkaz:
https://doaj.org/article/d2cbdc9cc15c4d2dac2dbf3f23206de8
Autor:
Yoonha Choi, Tiffany Ting Liu, Daniel G. Pankratz, Thomas V. Colby, Neil M. Barth, David A. Lynch, P. Sean Walsh, Ganesh Raghu, Giulia C. Kennedy, Jing Huang
Publikováno v:
BMC Genomics, Vol 19, Iss S2, Pp 147-159 (2018)
Abstract Background We developed a classifier using RNA sequencing data that identifies the usual interstitial pneumonia (UIP) pattern for the diagnosis of idiopathic pulmonary fibrosis. We addressed significant challenges, including limited sample s
Externí odkaz:
https://doaj.org/article/329f7601b00949389f738cafd747d729
Autor:
Gregory W. Randolph, Julie Ann Sosa, Yangyang Hao, Trevor E. Angell, David C. Shonka, Virginia A. LiVolsi, Paul W. Ladenson, Thomas C. Blevins, Quan-Yang Duh, Ronald Ghossein, Mack Harrell, Kepal Narendra Patel, Michael H. Shanik, S. Thomas Traweek, P. Sean Walsh, Michael W. Yeh, Amr H. Abdelhamid Ahmed, Allen S. Ho, Richard J. Wong, Joshua P. Klopper, Jing Huang, Giulia C. Kennedy, Richard T. Kloos, Peter M. Sadow
Publikováno v:
Thyroid : official journal of the American Thyroid Association, vol 32, iss 9
Background: Cytopathological evaluation of thyroid fine-needle aspiration biopsy (FNAB) specimens can fail to raise preoperative suspicion of medullary thyroid carcinoma (MTC). The Afirma RNA-sequencing MTC classifier identifies MTC among FNA samples
Autor:
Yoonha Choi, Jiayi Lu, Zhanzhi Hu, Daniel G. Pankratz, Huimin Jiang, Manqiu Cao, Cristina Marchisano, Jennifer Huiras, Grazyna Fedorowicz, Mei G. Wong, Jessica R. Anderson, Edward Y. Tom, Joshua Babiarz, Urooj Imtiaz, Neil M. Barth, P. Sean Walsh, Giulia C. Kennedy, Jing Huang
Publikováno v:
BMC Pulmonary Medicine, Vol 17, Iss 1, Pp 1-8 (2017)
Abstract Background Clinical guidelines specify that diagnosis of interstitial pulmonary fibrosis (IPF) requires identification of usual interstitial pneumonia (UIP) pattern. While UIP can be identified by high resolution CT of the chest, the results
Externí odkaz:
https://doaj.org/article/3a1d3e2eb73a4f0fa372dc7dc0a823f3
Autor:
Trevor E. Angell, Lori J. Wirth, Maria E. Cabanillas, Maisie L. Shindo, Edmund S. Cibas, Joshua E. Babiarz, Yangyang Hao, Su Yeon Kim, P. Sean Walsh, Jing Huang, Richard T. Kloos, Giulia C. Kennedy, Steven G. Waguespack
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Introduction: The Afirma® Xpression Atlas (XA) detects gene variants and fusions in thyroid nodule FNA samples from a curated panel of 511 genes using whole-transcriptome RNA-sequencing. Its intended use is among cytologically indeterminate nodules
Externí odkaz:
https://doaj.org/article/16a3057bc68d49a89d85ac502ac22e81