Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Giulia Brambilla Campart"'
Autor:
Patrizia Orsi, Giulia Brambilla Campart, M. Ghia, Eugenio Mereto, Antonietta Martelli, Cristina Porta Puglia, Roberto Carrozzino, Francesca Mattioli
Publikováno v:
Pharmacology & Toxicology. 86:129-134
Autor:
Giulia Brambilla Campart, Francesca Mattioli, Giovanni Brambilla, Antonietta Martelli, Giovanna Bergamaschi, Eugenio Mereto, Daniela Sini
Publikováno v:
Toxicology. 130:29-41
Omeprazole, a proton pump inhibitor of wide use in the treatment of gastric acid-related disorders, was evaluated for its genotoxic effects in both rat and human cultured cells and in the intact rat. DNA repair synthesis, as revealed by autoradiograp
Autor:
Roberta Canonero, Roberto Carrozzino, Francesca Mattioli, Luigi Robbiano, Antonietta Martelli, Marco Cavanna, Giulia Brambilla Campart
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 414:37-47
Auramine, a dye previously found to be a liver carcinogen in both mice and rats, was evaluated for its DNA-damaging and clastogenic activities in primary cultures of rats and human hepatocytes and for the induction of DNA single-strand breaks in the
Autor:
Francesca Mattioli, Luigi Robbiano, Giulia Brambilla Campart, Roberta Canonero, Antonietta Martelli
Publikováno v:
Mutagenesis. 12:35-40
The genotoxicity of p-dichlorobenzene (DCB) and hexachlorobenzene (HCB) was evaluated in primary cultures of rat and human hepatocytes. DNA fragmentation was measured by the alkaline elution technique and clastogenic activity by the increase in micro
Publikováno v:
Mutation Research/Genetic Toxicology. 322:1-8
Cinnamaldehyde, a widely used flavoring agent, has so far been subjected to a limited range of genotoxicity tests, mainly carried out in vitro, which produced contradictory results. Therefore we have examined cinnamaldehyde using additional in vivo g
Autor:
Antonietta Martelli, Giovanni Brambilla, A. Allavena, M. Ghia, Giulia Brambilla Campart, Eugenio Mereto
Publikováno v:
Carcinogenesis. 17(3)
The synthetic anti-androgen and progestin cyproterone acetate (CPA), recently found to be genotoxic for the liver, and two structurally similar progestins, chlormadinone acetate (CMA) and megestrol acetate (MGA), have been compared for clastogenic an
Autor:
Francesca Mattioli, Giulia Brambilla Campart, Antonietta Martelli, Roberta Canonero, Giovanni Brambilla
Publikováno v:
Toxicology and applied pharmacology. 131(2)
Metoclopramide (MCA) and procainamide (PCA), two widely used benzamide drugs developed before the present regulatory climate but recently found to induce DNA breaks in human lymphocytes, were evaluated for their genotoxic effects in cultured rodent a
Publikováno v:
Alternatives to Laboratory Animals. 17:22-27
A comparison of data from assays performed in cells of an established line derived from a human hepatoblastoma (Hep G2) with those previously obtained in freshly-isolated human hepatocytes, reveals that the latter are, by varying degrees, more sensit