Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Giulia, Fontemaggi"'
The lncRNAMALAT1-WTAP axis: a novel layer of EMT regulation in hypoxic triple-negative breast cancer
Autor:
Martina Dragonetti, Chiara Turco, Anna Benedetti, Frauke Goeman, Mattia Forcato, Stefano Scalera, Matteo Allegretti, Gabriella Esposito, Francesco Fazi, Giovanni Blandino, Sara Donzelli, Giulia Fontemaggi
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Early metastatic disease development is one characteristic that defines triple-negative breast cancer (TNBC) as the most aggressive breast cancer (BC) subtype. Numerous studies have identified long non-coding RNAs (lncRNA) as critical player
Externí odkaz:
https://doaj.org/article/e879368ac3de4165a4efafc2ff8ca490
Autor:
Federica Ganci, Matteo Allegretti, Carlotta Frascolla, Francesca Spinella, Francesca Rollo, Andrea Sacconi, Pascale De Valentina, Alina Catalina Palcau, Valentina Manciocco, Mariavittoria Vescovo, Ettore Cotroneo, Francesca Blandino, Maria Benevolo, Renato Covello, Paola Muti, Sabrina Strano, Antonello Vidiri, Giulia Fontemaggi, Raul Pellini, Giovanni Blandino
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-5 (2024)
Abstract Locoregional recurrences represent a frequently unexpected problem in head and neck squamous cell carcinoma (HNSCC). Relapse often (10–30%) occurs in patients with histologically negative resection margins (RMs), probably due to residual t
Externí odkaz:
https://doaj.org/article/4aec13763f344428a3a4e758c3570cc9
Autor:
Anna Benedetti, Chiara Turco, Enzo Gallo, Theodora Daralioti, Andrea Sacconi, Claudio Pulito, Sara Donzelli, Claudia Tito, Martina Dragonetti, Letizia Perracchio, Giovanni Blandino, Francesco Fazi, Giulia Fontemaggi
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-14 (2024)
Abstract Understanding the mechanisms of breast cancer cell communication underlying cell spreading and metastasis formation is fundamental for developing new therapies. ID4 is a proto-oncogene overexpressed in the basal-like subtype of triple-negati
Externí odkaz:
https://doaj.org/article/6a428de02f4a4444a6b19df3f26c4bbb
Autor:
Bianca Cesaro, Alessia Iaiza, Fabio Piscopo, Marco Tarullo, Eleonora Cesari, Dante Rotili, Antonello Mai, Alberto Diana, Michela Londero, Luca Del Giacco, Riccardo Masetti, Alba Di Leone, Chiara Naro, Silvia Masciarelli, Giulia Fontemaggi, Claudio Sette, Francesco Fazi, Alessandro Fatica
Publikováno v:
Cancer Communications, Vol 44, Iss 2, Pp 282-286 (2024)
Externí odkaz:
https://doaj.org/article/baa518cfe6ab4474b91c71eab5250df6
Autor:
Federica Ganci, Matteo Allegretti, Carlotta Frascolla, Francesca Spinella, Francesca Rollo, Andrea Sacconi, Valentina De Pascale, Alina Catalina Palcau, Valentina Manciocco, Mariavittoria Vescovo, Ettore Cotroneo, Francesca Blandino, Maria Benevolo, Renato Covello, Paola Muti, Sabrina Strano, Antonello Vidiri, Giulia Fontemaggi, Raul Pellini, Giovanni Blandino
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/a4d56f4acba344a694e658c89d6ee008
Autor:
Chiara Turco, Gabriella Esposito, Alessia Iaiza, Frauke Goeman, Anna Benedetti, Enzo Gallo, Theodora Daralioti, Letizia Perracchio, Andrea Sacconi, Patrizia Pasanisi, Paola Muti, Claudio Pulito, Sabrina Strano, Zaira Ianniello, Alessandro Fatica, Mattia Forcato, Francesco Fazi, Giovanni Blandino, Giulia Fontemaggi
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
The circular isoform of VEGFA mRNA (circ_0076611), associated with size and pathogenesis of triple-negative breast tumors, is produced via back splicing of exon-7 by a RNP complex comprising lncRNA-MALAT1, ID4 and SRSF1, and secreted through exosomes
Externí odkaz:
https://doaj.org/article/bc6a072f133f4fc982ec9fc88ab62c07
Autor:
Ori Hassin, Nishanth Belugali Nataraj, Michal Shreberk-Shaked, Yael Aylon, Rona Yaeger, Giulia Fontemaggi, Saptaparna Mukherjee, Martino Maddalena, Adi Avioz, Ortal Iancu, Giuseppe Mallel, Anat Gershoni, Inna Grosheva, Ester Feldmesser, Shifra Ben-Dor, Ofra Golani, Ayal Hendel, Giovanni Blandino, David Kelsen, Yosef Yarden, Moshe Oren
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The differential effects of TP53 missense mutations in colorectal cancer (CRC) remain to be explored. Here the authors compare the gain of function impact of two frequent TP53 mutations in CRC and show that p53R273 mutants control a transcriptional p
Externí odkaz:
https://doaj.org/article/a119b82dad0a479ebb369694272fe374
Autor:
Weronika Szukala, Agata Lichawska-Cieslar, Roza Pietrzycka, Maria Kulecka, Izabela Rumienczyk, Michal Mikula, Iwona Chlebicka, Piotr Konieczny, Katarzyna Dziedzic, Jacek C Szepietowski, Giulia Fontemaggi, Janusz Rys, Jolanta Jura
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-14 (2021)
Abstract Background Squamous cell carcinoma (SCC) of the skin is a common form of nonmelanoma skin cancer. Monocyte chemotactic protein 1-induced protein 1 (MCPIP1), also called Regnase-1, is an RNase with anti-inflammatory properties. In normal huma
Externí odkaz:
https://doaj.org/article/833340b85b4a40368a26a5f8e9aa7474
Autor:
Alessia Iaiza, Claudia Tito, Federica Ganci, Andrea Sacconi, Enzo Gallo, Silvia Masciarelli, Giulia Fontemaggi, Alessandro Fatica, Enrico Melis, Vincenzo Petrozza, Federico Venuta, Mirella Marino, Giovanni Blandino, Francesco Fazi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Thymic Epithelial Tumors (TETs) arise from epithelial cells of the thymus and are very rare neoplasms comprising Thymoma, Thymic carcinoma, and Thymic Neuroendocrine tumors that still require in-depth molecular characterization. Long non-coding RNAs
Externí odkaz:
https://doaj.org/article/d1f7dca372a14f409cad8aedd58895ec
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The miR-15/107 group of microRNAs (miRNAs) encloses 10 annotated human members and is defined based on the presence of the sequence AGCAGC near the mature miRNAs’ 5′ end. Members of the miR-15/107 group expressed in humans are highly evolutionari
Externí odkaz:
https://doaj.org/article/08e9323b28ea4a379c2c0ed485812ed9