Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Giulia, Calenda"'
Autor:
Natalia Teleshova, Marla J Keller, José A Fernández Romero, Barbara A Friedland, George W Creasy, Marlena G Plagianos, Laurie Ray, Patrick Barnable, Larisa Kizima, Aixa Rodriguez, Nadjet Cornejal, Claudia Melo, Gearoff Cruz Rodriguez, Sampurna Mukhopadhyay, Giulia Calenda, Shweta U Sinkar, Thierry Bonnaire, Asa Wesenberg, Shimin Zhang, Kyle Kleinbeck, Kenneth Palmer, Mohcine Alami, Barry R O'Keefe, Patrick Gillevet, Hong Hur, Yupu Liang, Gabriela Santone, Raina N Fichorova, Tamara Kalir, Thomas M Zydowsky
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0261775 (2022)
HIV pre-exposure prophylaxis (PrEP) is dominated by clinical therapeutic antiretroviral (ARV) drugs. Griffithsin (GRFT) is a non-ARV lectin with potent anti-HIV activity. GRFT's preclinical safety, lack of systemic absorption after vaginal administra
Externí odkaz:
https://doaj.org/article/71d1f80746cd4044a9318e97651b89ec
Autor:
Giulia Calenda, Ines Frank, Géraldine Arrode-Brusés, Amarendra Pegu, Keyun Wang, James Arthos, Claudia Cicala, Kenneth A Rogers, Lisa Shirreff, Brooke Grasperge, James L Blanchard, Stephanie Maldonado, Kevin Roberts, Agegnehu Gettie, Francois Villinger, Anthony S Fauci, John R Mascola, Elena Martinelli
Publikováno v:
PLoS Pathogens, Vol 15, Iss 5, p e1007776 (2019)
VRC01 protects macaques from vaginal SHIV infection after a single high-dose challenge. Infusion of a simianized anti-α4β7 mAb (Rh-α4β7) just prior to, and during repeated vaginal exposures to SIVmac251 partially protected macaques from vaginal S
Externí odkaz:
https://doaj.org/article/56f99e9871a14c77a113d5c201dca31e
Autor:
Meropi Aravantinou, Olga Mizenina, Giulia Calenda, Jessica Kenney, Ines Frank, Jeffrey D. Lifson, Moriah Szpara, Lichen Jing, David M. Koelle, Natalia Teleshova, Brooke Grasperge, James Blanchard, Agegnehu Gettie, Elena Martinelli, Nina Derby
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Herpes simplex virus 1 and 2 (HSV-1/2) similarly initiate infection in mucosal epithelia and establish lifelong neuronal latency. Anogenital HSV-2 infection augments the risk for sexual human immunodeficiency virus (HIV) transmission and is associate
Externí odkaz:
https://doaj.org/article/1f673356d51b44bbb4efd3d67140f2ad
Autor:
Guillermo Villegas, Giulia Calenda, Shweta Ugaonkar, Shimin Zhang, Larisa Kizima, Olga Mizenina, Agegnehu Gettie, James Blanchard, Michael L Cooney, Melissa Robbiani, José A Fernández-Romero, Thomas M Zydowsky, Natalia Teleshova
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159332 (2016)
Women need multipurpose prevention products (MPTs) that protect against sexually transmitted infections (STIs) and provide contraception. The Population Council has developed a prototype intravaginal ring (IVR) releasing the non-nucleoside reverse tr
Externí odkaz:
https://doaj.org/article/2c7ce7258bc743d49918758692207898
Autor:
Christine M. Fennessey, Maria Sole Cigoli, Peter D. Kwong, Brooke Grasperge, Agegnehu Gettie, Eun Sung Yang, John R. Mascola, James Blanchard, Ines Frank, Giulia Calenda, Marissa Fahlberg, Amarendra Pegu, Monica Vaccari, Thomas J. Hope, Reda Rawi, Cuiping Liu, Stephanie Maldonado, Gwo-Yu Chuang, Claudia Cicala, James Arthos, Elena Martinelli, Brandon F. Keele, Muhammad Shafique Arif, Anthony S. Fauci, Hui Geng, Tongqing Zhou
Publikováno v:
Science Translational Medicine. 13
Anti-HIV broadly neutralizing antibodies (bNAbs) may favor development of antiviral immunity by engaging the immune system during immunotherapy. Targeting integrin α4β7 with an anti-α4β7 monoclonal antibody (Rh-α4β7) affects immune responses in
Autor:
Diana Goode, Rosaline Truong, Guillermo Villegas, Giulia Calenda, Natalia Guerra-Perez, Michael Piatak, Jeffrey D Lifson, James Blanchard, Agegnehu Gettie, Melissa Robbiani, Elena Martinelli
Publikováno v:
PLoS Pathogens, Vol 10, Iss 12, p e1004567 (2014)
The availability of highly susceptible HIV target cells that can rapidly reach the mucosal lymphoid tissues may increase the chances of an otherwise rare transmission event to occur. Expression of α4β7 is required for trafficking of immune cells to
Externí odkaz:
https://doaj.org/article/61a983217bd64e148352e5468b30be3d
Autor:
Patrick Barnable, Giulia Calenda, Louise Ouattara, Agegnehu Gettie, James Blanchard, Ninochka Jean-Pierre, Larisa Kizima, Aixa Rodríguez, Ciby Abraham, Radhika Menon, Samantha Seidor, Michael L Cooney, Kevin D Roberts, Rhoda Sperling, Michael Piatak, Jeffrey D Lifson, Jose A Fernandez-Romero, Thomas M Zydowsky, Melissa Robbiani, Natalia Teleshova
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108109 (2014)
To extend our observations that single or repeated application of a gel containing the NNRTI MIV-150 (M) and zinc acetate dihydrate (ZA) in carrageenan (CG) (MZC) inhibits vaginal transmission of simian/human immunodeficiency virus (SHIV)-RT in macaq
Externí odkaz:
https://doaj.org/article/2e9ac8a52d7e461e9520d4b7745640d7
Autor:
Ines, Frank, Mariasole, Cigoli, Muhammad S, Arif, Marissa D, Fahlberg, Stephanie, Maldonado, Giulia, Calenda, Amarendra, Pegu, Eun Sung, Yang, Reda, Rawi, Gwo-Yu, Chuang, Hui, Geng, Cuiping, Liu, Tongqing, Zhou, Peter D, Kwong, James, Arthos, Claudia, Cicala, Brooke F, Grasperge, James L, Blanchard, Agegnehu, Gettie, Christine M, Fennessey, Brandon F, Keele, Monica, Vaccari, Thomas J, Hope, Anthony S, Fauci, John R, Mascola, Elena, Martinelli
Publikováno v:
Sci Transl Med
Anti-HIV broadly neutralizing antibodies (bNAbs) may favor development of antiviral immunity by engaging the immune system during immunotherapy. Targeting integrin α(4)β(7) with an anti-α(4)β(7) monoclonal antibody (Rh-α(4)β(7)) affects immune
Autor:
Michael L. Cooney, Natalia Teleshova, José A. Fernández-Romero, Patrick Barnable, Giulia Calenda, Agegnehu Gettie, Thomas M. Zydowsky, Keith Levendosky, Claudia Litterst, James F. Blanchard, Guillermo Villegas
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 74:e67-e74
The Population Council's microbicide gel MZC (also known as PC-1005) containing MIV-150 and zinc acetate dihydrate (ZA) in carrageenan (CG) has shown promise as a broad-spectrum microbicide against HIV, herpes simplex virus (HSV), and human papilloma
Autor:
H. Hur, Alexandra Reis, Giulia Calenda, Narender Kumar, Lisa Mamkina, Guillermo Villegas, Sampurna Mukhopadhyay, Tamara Kalir, Rhoda S. Sperling, Y. Liang, Natalia Teleshova, Lily Millen, Patrick Barnable
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Despite extensive studies suggesting increased susceptibility to HIV during the secretory phase of the menstrual cycle, the molecular mechanisms involved remain unclear. Our goal was to analyze transcriptomes of the endocervix and ectocervix during t