Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Giuditta Cuccuru"'
Autor:
Elisa Spaccarotella, Elisa Pellegrino, Manuela Ferracin, Cristina Ferreri, Giuditta Cuccuru, Cuiling Liu, Javeed Iqbal, Daniela Cantarella, Riccardo Taulli, Paolo Provero, Ferdinando Di Cunto, Enzo Medico, Massimo Negrini, Wing C. Chan, Giorgio Inghirami, Roberto Piva
Publikováno v:
Haematologica, Vol 99, Iss 1 (2014)
Systemic anaplastic large cell lymphoma is a category of T-cell non-Hodgkin’s lymphoma which can be further subdivided into two distinct entities (ALK+ and ALK−) based on the presence or absence of ALK gene rearrangements. Among several pathways
Externí odkaz:
https://doaj.org/article/d1e854803cfb49c19bc43e12a600befe
Autor:
Enrica Favini, Valentina Nicolini, Monica Tortoreto, Franco Zunino, Giuliana Cassinelli, Piera Mondellini, Italia Bongarzone, Patrizia Casalini, Cinzia Lanzi, Nadia Zaffaroni, Giovanna Petrangolini, Giuditta Cuccuru
Publikováno v:
Biochemical Pharmacology. 82:778-788
Emerging evidence suggests that Ret oncoproteins expressed in medullary thyroid cancer (MTC) might evade the pro-apoptotic function of the dependence receptor proto-Ret by directly impacting the apoptosis machinery. Identification of the molecular de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd485d964c2c58b7b7608c524f164fc
https://doi.org/10.1016/j.bcp.2011.06.037
https://doi.org/10.1016/j.bcp.2011.06.037
Autor:
Enrica Favini, Valentina Nicolini, Domenica Ronchetti, Michela Mattioli, Franco Zunino, Angela Greco, Giuditta Cuccuru, Cinzia Lanzi, Antonino Neri, Giuliana Cassinelli, Diletta Laccabue
Publikováno v:
Biochemical Pharmacology. 78:1139-1147
The identification of proliferation/survival pathways constitutively activated by genetic alterations in multiple myeloma (MM), or sustained by the bone marrow (BM) microenvironment, provides novel opportunities for the development of targeted therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355a77ec7af7faf0f9a5bc70bbd2f646
https://doi.org/10.1016/j.bcp.2009.06.023
https://doi.org/10.1016/j.bcp.2009.06.023
Autor:
Italia Bongarzone, L. Gorla, Giuliana Cassinelli, Mattia Cremona, Cinzia Lanzi, Giuditta Cuccuru, M. A. Pierotti, F. Miccichè, Piera Mondellini
Publikováno v:
Molecular Carcinogenesis. 48:220-231
Proteomics may help to elucidate differential signaling networks underlying the effects of compounds and to identify new therapeutic targets. Using a proteomic-multiplexed analysis of the phosphotyrosine signaling together with antibody-based validat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af523a147445d15cdcf75e4c076e2004
https://doi.org/10.1002/mc.20474
https://doi.org/10.1002/mc.20474
Autor:
Raffaella Cincinelli, Sabrina Dallavalle, Giuliana Cassinelli, Giuditta Cuccuru, Raffaella Nannei, Cinzia Lanzi, Eleonora Rizzi, Franco Zunino
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:3962-3968
A novel series of 3-arylureidobenzylidene-indolin-2-ones was synthesized and their inhibitory activity against Ret tyrosine kinase investigated in comparison with the Ret inhibitor RPI-1 as a reference compound for this series. A few compounds were a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb634ddbe61d9a6d376b419c972f7398
https://doi.org/10.1016/j.bmcl.2007.04.091
https://doi.org/10.1016/j.bmcl.2007.04.091
Publikováno v:
Annals of the New York Academy of Sciences. 1095:175-181
The proto-oncogene c-myc is involved in multiple cell pathways with opposite effects on cell outcome of death or proliferation. It has been proposed that these different roles depend on the sequestration of c-Myc protein in cellular compartments and/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::540d9d6eb09d0588d4d961a1f0e73263
https://doi.org/10.1196/annals.1397.021
https://doi.org/10.1196/annals.1397.021
Autor:
Sara Belluco, Rosanna Supino, Enrica Favini, Giuditta Cuccuru, Franco Zunino, A. Poletti, Giuliana Cassinelli, Diletta Laccabue, Monica Tortoreto, Giovanna Petrangolini, Graziella Pratesi, Cinzia Lanzi
Publikováno v:
Molecular Cancer Therapeutics. 5:2388-2397
Hepatocyte growth factor (HGF) and its tyrosine kinase receptor Met play a pivotal role in the tumor metastatic phenotype and represent attractive therapeutic targets. We investigated the biochemical and biological effects of the tyrosine kinase inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477cc09c0807d8b5117f16935a4f4439
https://doi.org/10.1158/1535-7163.mct-06-0245
https://doi.org/10.1158/1535-7163.mct-06-0245
Autor:
Giovanna Petrangolini, Sara Belluco, Graziella Pratesi, Giuliana Cassinelli, Franco Zunino, Giuditta Cuccuru, Monica Tortoreto, Cinzia Lanzi
Publikováno v:
Biochemical Pharmacology. 72:405-414
Recent evidence indicates that the success of molecular targeted therapies may depend on the identification of drug targets which are essential for the survival of subsets of tumors. RET oncogenes that have been implicated in the development of thyro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf65dfff1cc59bfb9aa238adb8ad5e5
https://doi.org/10.1016/j.bcp.2006.05.002
https://doi.org/10.1016/j.bcp.2006.05.002
Autor:
Cuiling Liu, Massimo Negrini, Roberto Piva, Paolo Provero, Giuditta Cuccuru, Elisa Pellegrino, Wing C. Chan, Giorgio Inghirami, Javeed Iqbal, Daniela Cantarella, Ferdinando Di Cunto, Manuela Ferracin, Riccardo Taulli, Enzo Medico, C Ferreri, Elisa Spaccarotella
Systemic anaplastic large cell lymphoma is a category of T-cell non-Hodgkin's lymphoma which can be further subdivided into two distinct entities (ALK(+) and ALK(-)) based on the presence or absence of ALK gene rearrangements. Among several pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8881d085846659588e3301e84a455be3
http://hdl.handle.net/2318/136677
http://hdl.handle.net/2318/136677
Autor:
Rosanna Supino, Giovanni Scambia, Cinzia Lanzi, Franco Zunino, Giuditta Cuccuru, Cristiano Ferlini, Giuliana Cassinelli, Valentina Zuco
Publikováno v:
The Prostate. 48:254-264
BACKGROUND Defects in the cell cycle machinery of prostate cancer cells might impair the efficiency of cell cycle checkpoints and affect the cell response to chemotherapeutic drugs. We examined the relationship between the status of microtubule damag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86de68237f9ae48540c85e301952cf12
https://doi.org/10.1002/pros.1105
https://doi.org/10.1002/pros.1105